De film speelt zich af in post-apocalyptisch 2018. John Connor heeft als lot het leiden van de opstand tegen Skynet en haar leger van Terminators. De toekomst die hij voorzag wordt veranderd door de komst van Marcus Wright, een vreemdeling wiens laatste herinnering is dat hij in een cel op de executie van zijn doodstraf zat te wachten. Connor moet bepalen of Marcus gezonden is vanuit de toekomst, of gered is vanuit het verleden. Samen trekken ze ten strijde tegen Skynet.
Ja! de film Terminator Salvation is nu beschikbaar om te kijken op Netflix in Nederland.
| Production | Jeffrey Silver | Producer |
| Sound | Danny Elfman | Original Music Composer |
| Art | Troy Sizemore | Art Direction |
| Production | Victor Kubicek | Producer |
| Writing | Michael Ferris | Writer |
| Art | Martin Laing | Production Design |
| Editing | Conrad Buff IV | Editor |
| Writing | John Brancato | Writer |
| Directing | McG | Director |
| Camera | Shane Hurlbut | Director of Photography |
| Production | Moritz Borman | Producer |
| Production | Derek Anderson | Producer |
| Costume & Make-Up | Robert Q. Mathews | Costume Supervisor |
| Costume & Make-Up | Michael Wilkinson | Costume Design |
| Production | Justine Arteta | Casting |
| Production | Kim Davis-Wagner | Casting |
| Costume & Make-Up | Kimberly Greene | Makeup Department Head |
| Crew | Hugo Dominguez | Digital Effects Supervisor |
| Writing | Steven E. Gordon | Storyboard |
| Production | Joel B. Michaels | Executive Producer |
| Production | Bruce Franklin | Associate Producer |
| Sound | Doug Hemphill | Sound Re-Recording Mixer |
| Sound | Cameron Frankley | Supervising Sound Editor |
| Camera | Glenn Brown | First Assistant Camera |
| Production | Don Zepfel | Production Manager |
| Production | Peter D. Graves | Executive Producer |
| Production | Andrew G. Vajna | Executive Producer |
| Sound | Mark Ulano | Production Sound Mixer |
| Editing | Carole A. Kenneally | First Assistant Editor |
| Production | Chantal Feghali | Co-Producer |
| Crew | Tom Struthers | Stunt Coordinator |
| Crew | Cesar Angobaldo | Transportation Captain |
| Production | Jeanne Allgood | Executive Producer |
| Camera | Richard Foreman Jr. | Still Photographer |
| Production | Nadia Paine | Production Supervisor |
| Production | April A. Janow | Associate Producer |
| Sound | Roland N. Thai | Sound Effects Editor |
| Art | Carol Kiefer | Art Department Coordinator |
| Production | Steve Gaub | Associate Producer |
| Directing | Trudy Ramirez | Script Supervisor |
| Camera | George Billinger III | Steadicam Operator |
| Art | Victor J. Zolfo | Set Decoration |
| Sound | Bill Abbott | Music Editor |
| Production | Dan Lin | Executive Producer |
| Production | Anjalika Mathur Nigam | Associate Producer |
| Sound | Lee Gilmore | Sound Effects Editor |
| Sound | Jason W. Jennings | Sound Designer |
| Camera | Chris Moseley | Camera Operator |
| Production | Don Zepfel | Associate Producer |
| Crew | William Ballard | Transportation Coordinator |
| Costume & Make-Up | Kathrine Gordon | Hair Department Head |
| Production | Mario Kassar | Executive Producer |
| Sound | Ron Bartlett | Sound Re-Recording Mixer |
| Sound | Ai-Ling Lee | Sound Designer |
| Visual Effects | John Walker | VFX Artist |
| Crew | Denise Gallo | Stunts |
| Costume & Make-Up | Melissa Yonkey | Hair Department Head |
| Costume & Make-Up | Betty Lou Skinner | Key Hair Stylist |
| Costume & Make-Up | Ed French | Makeup Artist |
| Costume & Make-Up | Lisa Taylor Roberts | Makeup Department Head |
| Costume & Make-Up | Erin Wooldridge | Key Makeup Artist |
| Costume & Make-Up | Deidre Parness | Makeup Artist |
| Costume & Make-Up | Christopher Trujillo | Makeup Artist |
| Costume & Make-Up | Rolf John Keppler | Makeup Artist |
| Costume & Make-Up | Joy Zapata | Hair Department Head |
| Sound | David V. Butler | Dialogue Editor |
| Directing | Bruce Franklin | First Assistant Director |
| Directing | Zach Hunter | Second Second Assistant Director |
| Directing | Aimée Schaefer | Script Supervisor |
| Directing | Paul Byrne Prenderville | Second Assistant Director |
| Directing | Kathy McHugh | Script Supervisor |
| Directing | Jeff Okabayashi | Second Assistant Director |
| Directing | Stephen P. Dunn | First Assistant Director |
| Directing | Bryan Snodgrass | Second Second Assistant Director |
| Directing | Lily García | Second Second Assistant Director |
| Directing | Charles Gibson | Second Unit Director |
| Directing | Cyndi Martin | Second Second Assistant Director |
| Directing | Katie Pruitt | Second Second Assistant Director |
| Camera | Adolfo Martínez Pérez | Additional Director of Photography |
| Visual Effects | Stan Winston | Creature Effects Technical Director |
| Crew | Mark Hicks | Stunts |
| Crew | Mark Hicks | Stunt Double |
| Crew | Stan Winston | In Memory Of |
| Visual Effects | Ben Snow | Visual Effects Supervisor |
| Visual Effects | Susan Greenhow | Visual Effects Producer |
| Visual Effects | Marc Chu | Animation Supervisor |
| Sound | Tom Hartig | Boom Operator |
| Art | Michael Sexton | Property Master |
| Production | Michael J. Burmeister | Location Manager |
| Art | Freddy Waff | Leadman |
| Costume & Make-Up | Ann Foley | Assistant Costume Designer |
| Production | Jacquelyn Palmquist | Casting Associate |
| Production | Freya Krasnow | Casting Assistant |
| Crew | Lee Anne Muldoon | Unit Publicist |
| Sound | Bob Beher | Foley Editor |
| Sound | Thomas J. O'Connell | ADR Mixer |
| Sound | Troy Porter | ADR Mixer |
| Sound | Rick Canelli | ADR Recordist |
| Sound | Jason Oliver | ADR Recordist |
| Production | Barbara Harris | ADR Voice Casting |
| Sound | John Roesch | Foley Artist |
| Sound | Alyson Dee Moore | Foley Artist |
| Sound | David Lee Fein | Foley Artist |
| Sound | Mary Jo Lang | Foley Mixer |
| Sound | Rick Wentworth | Conductor |
| Art | Greg John Callas | Construction Coordinator |
| Crew | Christian Alzmann | Visual Effects Art Director |
| Crew | Jim Milton | Visual Effects Editor |
| Camera | Patrick Loungway | Second Unit Director of Photography |
| Sound | Andy Potvin | Dolby Consultant |
| Visual Effects | Chantal Feghali | Visual Effects Producer |
| Crew | Dana Hee | Stunts |
| Crew | Ed Duran | Stunts |
| Crew | Kevin Black | Set Production Assistant |
| Crew | Angelique Midthunder | Stunts |
