Het verhaal speelt zich af in de kringen van de hippe, rijke jongeren in New York. White Mike is een jonge wannabe drugsdealer die stopt met zijn privé-school in de upper east side en zich volledig stort op zijn handeltje. Hij rookt en drinkt niet, maar bezoekt de feestjes enkel om zijn nieuwe drug 'twelve' te verkopen. Er ontstaan grote problemen voor Mike als zijn neef Charlie op straat wordt vermoord en zijn beste vriend wordt opgepakt als de dader.
Nee, helaas is Twelve nog niet beschikbaar op Netflix in Nederland.
| Directing | Joel Schumacher | Director |
| Writing | Jordan Melamed | Writer |
| Crew | Aaron Vexler | Stunt Driver |
| Production | Vanessa Hope | Associate Producer |
| Production | Jordan Melamed | Producer |
| Editing | Paul Zucker | Editor |
| Costume & Make-Up | Matthew Simonelli | Assistant Costume Designer |
| Costume & Make-Up | Joseph Whitmeyer | Key Hair Stylist |
| Writing | Nick McDonell | Novel |
| Crew | Ryan Washburn | Armorer |
| Costume & Make-Up | Evelyne Noraz | Makeup Department Head |
| Production | Robert Salerno | Producer |
| Production | Jessica Kelly | Casting |
| Production | Suzanne Smith Crowley | Casting |
| Crew | Conrad V. Brink Jr. | Special Effects Coordinator |
| Camera | Steven Fierberg | Director of Photography |
| Art | Ethan Tobman | Production Design |
| Production | Lauren Bass | Casting |
| Costume & Make-Up | David C. Robinson | Costume Design |
| Visual Effects | Joseph DiValerio | Visual Effects |
| Production | Sidonie Dumas | Producer |
| Production | Jordan Bass | Casting Associate |
| Costume & Make-Up | Colleen Callaghan | Hair Department Head |
| Production | Charlie Corwin | Producer |
| Editing | Gordon Grinberg | Editor |
| Art | Cherish M. Hale | Set Decoration |
| Production | Ted Field | Producer |
| Costume & Make-Up | Susan Wachsler | Costume Supervisor |
| Directing | Sharon Watt | Script Supervisor |
| Sound | Richard Mader | Sound Mixer |
| Camera | Myles Aronowitz | Still Photographer |
| Sound | Harry Gregson-Williams | Original Music Composer |
| Sound | Sean Garnhart | Sound Re-Recording Mixer |
| Sound | Tony Volante | Sound Re-Recording Mixer |
| Sound | Sean Garnhart | Sound Designer |
| Sound | Sean Garnhart | Supervising Sound Editor |
| Directing | Steve Apicella | First Assistant Director |
| Sound | Marissa Littlefield | ADR Editor |
| Sound | Steve Giammaria | Sound Recordist |
| Sound | Fred Rosenberg | Dialogue Editor |
| Art | Karl Lake | Art Department Assistant |
