Wanneer Manuela haar 17-jarige zoon Esteban verliest bij een auto-ongeluk reist ze af naar Barcelona om zijn vader het droevige nieuws te vertellen. Esteban's vader gaat tegenwoordig als vrouw door het leven en heeft nooit van het bestaan van zijn zoon geweten.
Nee, helaas is Todo sobre mi madre nog niet beschikbaar op Netflix in Nederland.
| Costume & Make-Up | Bina Daigeler | Costume Design |
| Directing | Pedro Almodóvar | Director |
| Editing | José Salcedo | Editor |
| Art | Antxón Gómez | Production Design |
| Camera | Affonso Beato | Director of Photography |
| Production | Sara Bilbatúa | Casting |
| Sound | José Antonio Bermúdez | Sound Designer |
| Sound | Miguel Rejas | Sound Designer |
| Sound | Diego Garrido | Sound Designer |
| Sound | Alberto Iglesias | Original Music Composer |
| Crew | Antonio Molina | Special Effects |
| Crew | Pierre Edelman | Thanks |
| Art | Federico García Cambero | Set Decoration |
| Editing | Manuel Laguna | Assistant Editor |
| Crew | Cayetana Guillén Cuervo | Thanks |
| Directing | Yuyi Beringola | Script Supervisor |
| Camera | José Ramón Delgado | First Assistant Camera |
| Production | Pilar Moya | Casting |
| Production | Mamen Moya | Casting |
| Editing | Rosa Ortiz | Assistant Editor |
| Directing | Lola García | Assistant Director |
| Costume & Make-Up | Jorge Hernández Lobo | Makeup Artist |
| Lighting | Enrique Bello | Gaffer |
| Costume & Make-Up | José María de Cossío | Costume Design |
| Costume & Make-Up | Jean-Jacques Puchu | Hairstylist |
| Crew | Ismael Martínez | Stunts |
| Lighting | Fernando Beltrán | Electrician |
| Production | Agustín Almodóvar | Executive Producer |
| Production | Claude Berri | Co-Producer |
| Production | Michel Ruben | Associate Producer |
| Costume & Make-Up | Juan Pedro Hernández | Makeup Artist |
| Writing | Pedro Almodóvar | Screenplay |
