Amy, Dominique, Max and Janet zijn zeer jonge maar vooral zeer sexy D.E.B.S oftewel 'special agents', die 'undercover' werken voor de regering. Regelmatig wordt een beroep gedaan op de meiden om de wereld te verlossen van menige snoodaard. In schooluniformen, trekt het dappere viertal ten strijde. Tijdens één van hun missies gaat het echter mis; Amy wordt gegijzeld door juwelendief Lucy Diamond. Terwijl de andere D.E.B.S. denken dat Amy in gevaar is en zich op een reddingsplan beramen, wordt Amy volslagen verliefd op haar voormalige vijand Lucy. Zal Amy de D.E.B.S vaarwel zeggen om met Lucy de horizon tegemoet te gaan? Of zal ze de liefde van haar leven aan zich voor bij laten gaan vanwege haar roeping om de wereld van slechteriken te ontdoen?
Nee, helaas is D.E.B.S. nog niet beschikbaar op Netflix in Nederland.
| Camera | M. David Mullen | Director of Photography |
| Production | Jasmine Kosovic | Producer |
| Production | Andrea Sperling | Producer |
| Writing | Angela Robinson | Screenplay |
| Directing | Angela Robinson | Director |
| Production | Rick Montgomery | Casting |
| Art | Chris Anthony Miller | Production Design |
| Editing | Angela Robinson | Editor |
| Sound | Messy | Original Music Composer |
| Crew | Tom Waite | Stunts |
| Sound | Steven M. Stern | Original Music Composer |
| Sound | Howard Paar | Music Supervisor |
| Costume & Make-Up | Frank Helmer | Costume Design |
| Directing | Diana Valentine | Script Supervisor |
| Sound | Wayne Scott Joness | Music Editor |
| Crew | Lynn Salvatori | Stunt Coordinator |
| Camera | Bruce Birmelin | Still Photographer |
| Art | Laura Evans | Set Decoration |
| Costume & Make-Up | Rosemary Lawrence | Key Makeup Artist |
| Costume & Make-Up | Marc Boyle | Key Hair Stylist |
| Costume & Make-Up | Angie Wells | Makeup Artist |
| Directing | Hillary Schwartz | Second Assistant Director |
| Directing | Sholto J. Roeg | First Assistant Director |
| Crew | Nicole Basanda | Stunts |
| Crew | Dartenea Bryant | Stunts |
| Crew | Terri Cadiente | Stunts |
| Crew | Daniel Arrias | Stunts |
| Crew | Dale Gibson | Stunts |
| Crew | Tom Harper | Stunts |
| Crew | Ritchie Copenhaver | Stunts |
| Crew | Will Leong | Stunts |
| Crew | Toby Holguin | Stunts |
| Crew | Cliff McLaughlin | Stunts |
| Crew | Alex Madison | Stunts |
| Crew | Brad Orrison | Stunts |
| Crew | Joel Munoz | Stunts |
| Crew | Jill Stokesberry | Stunts |
| Crew | Monica Staggs | Stunts |
| Crew | Mark Vanselow | Stunts |
| Crew | Mike Smith | Fight Choreographer |
| Crew | Boni Yanagisawa | Stunts |
| Lighting | Skip McCraw | Gaffer |
| Production | Stacy Codikow | Co-Producer |
| Production | Pat Scanlon | Co-Producer |
| Production | Alexandra Kondracke | Associate Producer |
| Production | Larry Kennar | Executive Producer |
| Production | Douglas Salkin | Associate Producer |
