Amy, Dominique, Max and Janet zijn zeer jonge maar vooral zeer sexy D.E.B.S oftewel 'special agents', die 'undercover' werken voor de regering. Regelmatig wordt een beroep gedaan op de meiden om de wereld te verlossen van menige snoodaard. In schooluniformen, trekt het dappere viertal ten strijde. Tijdens één van hun missies gaat het echter mis; Amy wordt gegijzeld door juwelendief Lucy Diamond. Terwijl de andere D.E.B.S. denken dat Amy in gevaar is en zich op een reddingsplan beramen, wordt Amy volslagen verliefd op haar voormalige vijand Lucy. Zal Amy de D.E.B.S vaarwel zeggen om met Lucy de horizon tegemoet te gaan? Of zal ze de liefde van haar leven aan zich voor bij laten gaan vanwege haar roeping om de wereld van slechteriken te ontdoen?
Nee, helaas is D.E.B.S. nog niet beschikbaar op Netflix in Nederland.
| Sound | Messy | Original Music Composer |
| Art | Chris Anthony Miller | Production Design |
| Editing | Angela Robinson | Editor |
| Writing | Angela Robinson | Screenplay |
| Directing | Angela Robinson | Director |
| Camera | M. David Mullen | Director of Photography |
| Production | Andrea Sperling | Producer |
| Production | Jasmine Kosovic | Producer |
| Production | Rick Montgomery | Casting |
| Crew | Tom Waite | Stunts |
| Sound | Steven M. Stern | Original Music Composer |
| Crew | Joel Munoz | Stunts |
| Crew | Boni Yanagisawa | Stunts |
| Art | Laura Evans | Set Decoration |
| Crew | Cliff McLaughlin | Stunts |
| Costume & Make-Up | Rosemary Lawrence | Key Makeup Artist |
| Crew | Ritchie Copenhaver | Stunts |
| Crew | Daniel Arrias | Stunts |
| Lighting | Skip McCraw | Gaffer |
| Crew | Dale Gibson | Stunts |
| Crew | Brad Orrison | Stunts |
| Crew | Monica Staggs | Stunts |
| Crew | Will Leong | Stunts |
| Crew | Nicole Basanda | Stunts |
| Crew | Tom Harper | Stunts |
| Crew | Toby Holguin | Stunts |
| Crew | Terri Cadiente | Stunts |
| Crew | Jill Stokesberry | Stunts |
| Crew | Mark Vanselow | Stunts |
| Costume & Make-Up | Marc Boyle | Key Hair Stylist |
| Directing | Sholto J. Roeg | First Assistant Director |
| Production | Larry Kennar | Executive Producer |
| Production | Pat Scanlon | Co-Producer |
| Production | Stacy Codikow | Co-Producer |
| Production | Alexandra Kondracke | Associate Producer |
| Costume & Make-Up | Angie Wells | Makeup Artist |
| Directing | Hillary Schwartz | Second Assistant Director |
| Crew | Dartenea Bryant | Stunts |
| Crew | Alex Madison | Stunts |
| Crew | Mike Smith | Fight Choreographer |
| Production | Douglas Salkin | Associate Producer |
| Directing | Diana Valentine | Script Supervisor |
| Crew | Lynn Salvatori | Stunt Coordinator |
| Camera | Bruce Birmelin | Still Photographer |
| Sound | Howard Paar | Music Supervisor |
| Costume & Make-Up | Frank Helmer | Costume Design |
| Sound | Wayne Scott Joness | Music Editor |
| Sound | Doug Andham | Sound Effects Editor |
| Sound | Jesse Pomeroy | Supervising Sound Editor |
| Sound | Adam Stiles | Sound Effects Editor |
| Sound | Sergio Reyes | Sound Re-Recording Mixer |
| Crew | Torrence Hall | Special Effects |
| Sound | Steve Tushar | Sound Designer |
| Crew | Mike Tristano | Special Effects |
| Camera | Michael Gfelner | Camera Operator |
| Crew | Mike Tristano | Armorer |
| Visual Effects | David Tecson | Visual Effects Supervisor |
| Visual Effects | Mark Thompson | Visual Effects Supervisor |
| Production | Mike Crawford | Line Producer |
| Production | Mike Crawford | Unit Production Manager |
| Camera | Theo Pingarelli | First Assistant Camera |
| Camera | Steve Whitcomb | Second Assistant Camera |
| Art | Greg Runnels | Set Dresser |
| Art | Mark Runnels | Set Dresser |
| Art | Morgan Blackledge | Set Dresser |
