Alex Cross, politie-inspecteur en doctor in de psychologie te Washington, verneemt dat zijn nichtje, die rechten studeert in Noord-Carolina, is verdwenen en waarschijnlijk werd ontvoerd. Hij haast zich naar Durham om er aan de zoekacties deel te nemen. Ver buiten zijn gezagsgebied en tot grote wrevel van de plaatselijke speurders, begint hij zijn eigen onderzoek. Dankzij zijn buitengewoon deductievermogen ontdekt hij dat er eigenlijk acht meisjes verdwenen zijn, en dat een van hen net vermoord werd teruggevonden.
| Editing | Harvey Rosenstock | Editor |
| Writing | James Patterson | Novel |
| Directing | Gary Fleder | Director |
| Production | Deborah Aquila | Casting |
| Production | David Brown | Producer |
| Production | Joe Wizan | Producer |
| Production | C.O. Erickson | Executive Producer |
| Production | Jane Shannon-Smith | Casting |
| Sound | Mark Isham | Original Music Composer |
| Writing | David Klass | Screenplay |
| Editing | William Steinkamp | Editor |
| Art | Nelson Coates | Production Design |
| Camera | Aaron Schneider | Director of Photography |
| Crew | Erik Rondell | Stunts |
| Crew | Sandy Berumen | Stunt Double |
| Directing | Trey Batchelor | Second Assistant Director |
| Crew | Cliff McLaughlin | Stunts |
| Crew | Norman Howell | Stunts |
| Camera | Rick Bota | Second Unit Director of Photography |
| Directing | Rick Bota | Second Unit Director |
| Crew | Tony Donno | Stunts |
| Directing | Michael Zimbrich | First Assistant Director |
| Crew | Rick Avery | Stunts |
| Crew | Tabby Hanson | Stunts |
| Crew | Chuck Picerni Jr. | Stunt Coordinator |
| Lighting | Dwight Campbell | Chief Lighting Technician |
| Crew | Jophery C. Brown | Stunt Double |
| Crew | Jennifer Watson-Johnston | Stunts |
| Production | C.O. Erickson | Unit Production Manager |
| Sound | Peter Afterman | Music Supervisor |
| Camera | Harry Zimmerman | Second Assistant Camera |
| Camera | Bill Brummond | Steadicam Operator |
| Camera | David Boyd | Camera Operator |
| Production | Steve Wizan | Co-Producer |
| Editing | Armen Minasian | Additional Editor |
| Production | Cindy Hochman | Production Coordinator |
| Directing | Nancy Blewer | Second Second Assistant Director |
| Camera | Kevin Wadowski | First Company Grip |
| Camera | Terry Pfrang | First Assistant Camera |
| Sound | Lee Orloff | Sound Mixer |
| Art | Barry Franenberg | Property Master |
| Directing | Elizabeth Ludwick-Bax | Script Supervisor |
| Directing | Chuck Picerni Jr. | Second Unit Director |
| Crew | Jimmy N. Roberts | Stunts |
| Costume & Make-Up | Ben Nye Jr. | Makeup Artist |
| Sound | Kerry Dean Williams | Dialogue Editor |
| Sound | Scott Curtis | Foley Editor |
| Sound | David Lee Fein | Foley Artist |
| Sound | Robin Harlan | Foley Artist |
| Editing | Phil Hetos | Color Timer |
| Editing | Theresa Repola Mohammed | Negative Cutter |
| Sound | Ken Dufva | Foley Artist |
| Sound | Susan Kurtz | Sound Effects Editor |
| Sound | John Dunn | Sound Editor |
| Art | Joseph Hodges | Art Direction |
| Costume & Make-Up | Jeffrey Hamilton | Makeup Artist |
| Sound | Tammy Fearing | Foley Editor |
| Art | Linda Lee Sutton | Set Decoration |
| Sound | Jeff Clark | Sound Editor |
| Sound | Darrell Hanzalik | ADR Editor |
| Sound | Michael J. Benavente | Sound Editor |
| Costume & Make-Up | Leonard MacDonald | Special Effects Makeup Artist |
| Sound | Spike Allison Hooper | Assistant Sound Editor |
| Sound | Nicholas R. Allen | Boom Operator |
| Sound | Sarah Monat | Foley Artist |
| Sound | David B. Cohn | Sound Editor |
| Art | Brian Bird | Art Department Coordinator |
| Costume & Make-Up | Abigail Murray | Costume Designer |
| Crew | Rick Picerni | Stunts |
| Camera | Tom Ryan | First Assistant Camera |
| Camera | Sumi Yang | Camera Loader |
| Crew | Thomas A. Payne | Cableman |
| Art | Rick Bioni | Assistant Property Master |
| Art | Jim LaBarge | Leadman |
| Production | Judd Nissen | Assistant Production Coordinator |
| Art | James Harper | Set Dresser |
| Art | R.A. Tony Poland | Set Dresser |
| Art | Paul Penley | Set Dresser |
| Art | Eric Troop | Set Dresser |
| Art | Rick Chinelli | Set Dresser |
| Art | Lisa Goldsmith | Set Dresser |
| Art | Tracy Morris Johnson | Set Dresser |
| Production | Louis Phillips | Production Accountant |
| Production | David M. Rodriguez | First Assistant Accountant |
| Production | Steve Aaron Schultz | Production Secretary |
| Lighting | Simone Perusse | Assistant Chief Lighting Technician |
| Lighting | Patric J. Abaravich | Assistant Chief Lighting Technician |
| Lighting | Scott Toland | Electrician |
| Lighting | Michael Lyon | Electrician |
| Lighting | R. Adam Chambers | Rigging Gaffer |
| Camera | Richard Kuhn | Second Company Grip |
| Camera | Darrell B. Sheldon | Dolly Grip |
| Camera | Dietmar Wendelin | Dolly Grip |
| Camera | Mark Volpe | Grip |
| Camera | Walter 'T.J.' Johnson | Grip |
| Art | Douglas Womack | Construction Coordinator |
| Art | Randlett King Lawrence | Construction Foreman |
| Art | Jeff Brown | Greensman |
| Production | Sean Taylor | Production Coordinator |
| Art | Taishiro Kiya | Conceptual Design |
| Art | David Dupuis | Conceptual Design |
| Costume & Make-Up | Frances Mathias | Hair Department Head |
| Costume & Make-Up | Doug Kirkpatrick | Hairstylist |
| Costume & Make-Up | Paul H. Lopez | Costume Supervisor |
| Costume & Make-Up | Valerie Zielonka | Costume Supervisor |
| Costume & Make-Up | Jennifer Day Young | Set Costumer |
| Costume & Make-Up | Alan Martin | Set Costumer |
| Production | James McCabe | Location Manager |
| Editing | Tony Ciccone | First Assistant Editor |
| Editing | Joe Mosca | Assistant Editor |
| Editing | Christopher S. Capp | Assistant Editor |
| Editing | Debra L. Tennant | Assistant Editor |
| Sound | David Bartlett | Supervising Sound Editor |
| Sound | David Williams | Supervising Dialogue Editor |
| Sound | Renée Tondelli | Supervising ADR Editor |
| Sound | Bill Ward | Assistant Sound Editor |
| Sound | Paul O'Bryan | Assistant Sound Editor |
| Sound | Bob Baron | ADR Mixer |
| Sound | Randy K. Singer | Foley Mixer |
| Production | Barbara Harris | ADR Voice Casting |
| Sound | Rick Ash | Sound Re-Recording Mixer |
| Sound | Gary Alexander | Sound Re-Recording Mixer |
| Sound | Tom Carlson | Music Editor |
| Sound | Dick Bernstein | Music Editor |
| Sound | Ken Kugler | Orchestrator |
| Sound | Ken Kugler | Conductor |
| Sound | Stephen Krause | Scoring Mixer |
| Production | Jennifer Kunishima | Producer's Assistant |
| Production | Doris Wood | Producer's Assistant |
| Crew | Quentin Pierre | Actor's Assistant |
| Crew | Corey Gray | Actor's Assistant |
| Crew | Brian Regalot | Actor's Assistant |
| Crew | Trina Mitchum | Actor's Assistant |
| Production | John Rash | Assistant Accountant |
| Production | Carmen C. Avila | Assistant Accountant |
| Production | Steven M. Boyd | Assistant Accountant |
| Production | Denise Mora | Assistant Accountant |
| Crew | Eileen A. O'Donnell | Clearances Coordinator |
| Crew | Park Dietz | Technical Advisor |
| Production | Alex Rosenberg | Casting Associate |
| Production | Dayna Polehanki | Casting Assistant |
| Crew | Howard B. Davidson | Transportation Coordinator |
| Crew | Gary Paulsen | Transportation Captain |
| Crew | Robert A. Levine | Unit Publicist |
| Camera | Kimberly Wright | Still Photographer |
| Crew | John Peyser | Special Effects Coordinator |
| Crew | Michael D. Starks | Craft Service |
| Crew | Derek Hurd | Craft Service |
| Camera | Andrew Casey | "B" Camera Operator |
| Camera | Bo Webb | Second Assistant Camera |
| Art | Burton Rencher | Art Direction |
| Art | Stewart 'Polar Bear' Shaw | Leadman |
| Art | Alex L. Ferguson | Props |
| Art | Peter Battistelli | Construction Coordinator |
| Art | Geoffrey Cormier | Greensman |
| Production | Diane Ward | Assistant Production Coordinator |
| Production | Vick Griffin | Location Manager |
| Crew | Reva Grantham | Craft Service |
| Crew | Mike Schorr | Special Effects Coordinator |
| Directing | Michael Kahn | Second Unit First Assistant Director |
| Camera | Rexford L. Metz | Second Unit Director of Photography |
| Camera | Alec Hirschfeld | Camera Operator |
| Camera | Marc Hirschfeld | First Assistant Camera |
| Camera | Daniel Galiardi | Second Assistant Camera |
| Camera | Rexford L. Metz | Aerial Camera |
| Lighting | Keith Pickett | Chief Lighting Technician |
| Camera | David Noble | First Company Grip |
| Camera | Ben Noble | Second Company Grip |
| Camera | Scott Johnson | Aerial Camera Technician |
| Crew | Steve Hand | Aerial Coordinator |
| Art | Jonathan Silver | Title Designer |
| Production | Michael G. Jefferson | Production Assistant |
| Production | Rick Kelly | Production Assistant |
| Production | Gian Temperilli | Production Assistant |
| Production | Robert Colicci | Production Assistant |
| Production | Patrick Guzzo | Production Assistant |
| Production | Keith Popely | Production Assistant |
| Production | Kyle Kaufman | Production Assistant |
| Production | Burton L. Warner | Production Assistant |
| Production | Ray Blanchard | Production Assistant |
| Production | Kevin M. Jackson | Production Assistant |
| Production | Michael Triandafils | Production Assistant |
| Production | Brad Sykes | Production Assistant |
| Production | Susan K. Hoover | Production Assistant |
| Production | Kurt Zelnak | Production Assistant |
| Production | David Curtis | Production Assistant |
| Production | Kelly King | Production Assistant |
| Production | Leigh Bragassa | Production Assistant |
