De 22-jarige drugsdealer Chris (Emile Hirsch) schakelt huurmoordenaar Joe Cooper (Ma hew McConaughey) in om zijn moeder uit de weg te ruimen. Met de uitkering van haar levensverzekering kan Chris zijn schulden afbetalen. De slechtgemanierde huurmoordenaar wil de klus wel klaren, op voorwaarde dat Chris' zusje Dottie (Juno Temple) als seksueel onderpand dient totdat hij betaald krijgt. Met tegenzin besluit Chris zijn schuld boven het welzijn van zijn zus te stellen en stemt in met het aanbod. Maar wat als hij het geld nooit bij elkaar krijgt
Nee, helaas is Killer Joe nog niet beschikbaar op Netflix in Nederland.
| Directing | William Friedkin | Director |
| Writing | Tracy Letts | Screenplay |
| Camera | Caleb Deschanel | Director of Photography |
| Production | Nicolas Chartier | Producer |
| Costume & Make-Up | Peggy Schnitzer | Costume Design |
| Production | Scott Einbinder | Producer |
| Production | Denise Chamian | Casting |
| Production | Christopher Woodrow | Executive Producer |
| Crew | Danny Epper | Stunts |
| Production | Vicki Cherkas | Executive Producer |
| Production | Laurence Freed | Co-Executive Producer |
| Production | Ryan Westheimer | Line Producer |
| Production | Jenn Lee | Production Supervisor |
| Editing | Darrin Navarro | Editor |
| Art | Franco-Giacomo Carbone | Production Design |
| Art | Alice Baker | Set Decoration |
| Production | Zev Foreman | Executive Producer |
| Production | Patrick Newall | Co-Producer |
| Production | Patrick Newall | Unit Production Manager |
| Production | Molly Conners | Executive Producer |
| Production | Jamin O'Brien | Co-Executive Producer |
| Production | Eli Selden | Associate Producer |
| Sound | Steve Boeddeker | Sound Designer |
| Art | Nicole LaBranche | Art Department Coordinator |
| Art | Jason Portera | Set Dresser |
| Crew | Rick Broderman | Scenic Artist |
| Art | Lindanne Lewis | Painter |
| Crew | James J. Hershey | Propmaker |
| Costume & Make-Up | Cory Parker | On Set Dresser |
| Art | Charles Bodenheimer | Painter |
| Art | Jeffrey Pratt Gordon | Assistant Property Master |
| Art | Vanessa Merrill | Graphic Designer |
| Crew | Mark T. Henderson | Propmaker |
| Art | Brook Yeaton | Property Master |
| Art | Wendy Guerrera | Painter |
| Art | April LaBranche | Art Department Coordinator |
| Art | David Lee Toth | Set Dresser |
| Art | Patcharee Blanchard | Set Dresser |
| Art | Paul Blanchard | Leadman |
| Art | Ember Soberman | Painter |
| Art | Sian C. Sanzone | Painter |
| Art | Marcus Turchi | Construction Coordinator |
| Art | Spencer J. Abadie | Construction Buyer |
| Crew | Jeff Garbacz | Propmaker |
| Sound | Tyler Bates | Original Music Composer |
| Crew | O.J. Knighten | Animal Wrangler |
| Directing | George Bott | Second Assistant Director |
| Costume & Make-Up | Marcos Gonzales | Key Hair Stylist |
| Costume & Make-Up | Kent Richard | Assistant Hairstylist |
| Directing | Chuck Picerni Jr. | Second Unit Director |
| Costume & Make-Up | Donna Spahn | Assistant Hairstylist |
| Costume & Make-Up | Allison Bauserman | Set Costumer |
| Crew | Chuck Picerni Jr. | Stunt Coordinator |
| Directing | Michael Salven | First Assistant Director |
| Costume & Make-Up | Krystal Kershaw | Makeup Department Head |
| Production | Giancarlo J. Sini | Production Manager |
| Costume & Make-Up | Adrienne Lynn | Assistant Makeup Artist |
| Production | Lauren Claret | Consulting Accountant |
| Art | Courtney Talbot | Set Decoration |
| Sound | Alexandra Fehrman | Sound Editor |
| Sound | C.C. Adcock | Music Supervisor |
| Sound | King Cotton | Music Consultant |
| Sound | Alexandra Fehrman | Music Editor |
| Directing | Sandy Parker | Script Supervisor |
| Writing | Tracy Letts | Writer |