In Venice Beach komt naïeveling JB samen met KG en ze vormen de rockband Tenacious D. Omdat ze de beste rockband aller tijden willen worden en dat niet zo gemakkelijk gaat, stelen ze wat ze denken dat hen kan helpen in hun tocht naar het sterrendom: een magisch plectrum van een rock-and-roll museum 300 mijlen verder.
Nee, helaas is Tenacious D in The Pick of Destiny nog niet beschikbaar op Netflix in Nederland.
| Production | Jack Black | Producer |
| Production | Kyle Gass | Producer |
| Production | Stuart Cornfeld | Producer |
| Editing | David Rennie | Editor |
| Directing | Liam Lynch | Director |
| Crew | Mic Rodgers | Stunts |
| Crew | Brian Machleit | Stunts |
| Sound | Derek Vanderhorst | Sound Effects Editor |
| Directing | Heather Grierson | Second Assistant Director |
| Crew | Steve Hart | Stunts |
| Crew | Angelique Midthunder | Stunt Driver |
| Crew | Scotty Richards | Stunt Coordinator |
| Crew | Sean Graham | Stunts |
| Crew | Frank Torres | Stunts |
| Crew | Ian Quinn | Stunts |
| Crew | Tom Elliott | Stunts |
| Crew | Larry Rippenkroeger | Stunts |
| Crew | Danny Wynands | Stunts |
| Crew | Rick Miller | Stunt Double |
| Crew | Terry Jackson | Stunts |
| Crew | Michael Hugghins | Stunts |
| Crew | Tim Trella | Stunts |
| Crew | Roger Richman | Stunts |
| Crew | Ed McDermott II | Stunt Driver |
| Sound | Marc Glassman | Sound Effects Editor |
| Crew | Buck McDancer | Stunts |
| Crew | Jody Hart | Stunt Driver |
| Crew | Dean Bailey | Stunts |
| Crew | Kevin Abercrombie | Stunts |
| Visual Effects | John Coats | Visual Effects |
| Sound | Elmo Weber | Supervising Sound Editor |
| Directing | Velvet Andrews-Smith | Second Second Assistant Director |
| Directing | Milos Milicevic | First Assistant Director |
| Costume & Make-Up | Barney Burman | Makeup Designer |
| Crew | Lisa Avery | Stunts |
| Art | Mike Piccirillo | Art Department Coordinator |
| Sound | Kyle Gass | Songs |
| Sound | Orada Jusatayanond | Sound Effects Editor |
| Sound | Clayton Weber | Sound Effects Editor |
| Production | Erik Holmberg | Executive In Charge Of Production |
| Directing | Pamela Alch | Script Supervisor |
| Visual Effects | Bill Church | Visual Effects |
| Crew | Andy Weder | Special Effects Coordinator |
| Production | Ralph Bertelle | Production Supervisor |
| Costume & Make-Up | Linda Flowers | Hair Department Head |
| Crew | Jeff Brockton | Stunts |
| Crew | Robert Chapin | Stunts |
| Costume & Make-Up | Merribelle Anderson | Key Hair Stylist |
| Camera | Michael FitzMaurice | Camera Operator |
| Crew | Mike Avery | Stunts |
| Sound | David Bach | Supervising Sound Editor |
| Costume & Make-Up | Kate Shorter | Makeup Department Head |
| Visual Effects | David D. Johnson | Visual Effects Supervisor |
| Directing | Ivan Kraljević | Second Second Assistant Director |
| Camera | Jon Myers | Steadicam Operator |
| Costume & Make-Up | Ralis Kahn | Makeup Artist |
| Sound | Jack Black | Songs |
| Camera | Zade Rosenthal | Still Photographer |
| Visual Effects | Brent M. Bowen | Visual Effects |
| Costume & Make-Up | Toni G | Special Effects Makeup Artist |
| Costume & Make-Up | Mike Marino | Special Effects Makeup Artist |
| Costume & Make-Up | Scott Stoddard | Special Effects Makeup Artist |
| Costume & Make-Up | Yeşim "Shimmy" Osman | Hairstylist |
| Art | Don Diers | Set Decoration |
| Costume & Make-Up | Hope Slepak | Costume Supervisor |
| Camera | David B. Nowell | Aerial Director of Photography |
| Costume & Make-Up | Justin Stafford | Special Effects Makeup Artist |
| Camera | Paul Hughen | Second Unit Director of Photography |
| Costume & Make-Up | Mike Smithson | Special Effects Makeup Artist |
| Camera | Thomas Vandermillen | First Assistant Camera |
| Crew | Cole S. McKay | Stunt Double |
| Art | David Hartman | Production Illustrator |
| Crew | Joni Avery | Stunts |
| Crew | Eliza Coleman | Stunts |
| Crew | Doug Coleman | Stunts |
| Crew | Jack Gill | Stunts |
| Directing | Rick Avery | Second Unit Director |
| Art | Maria Baker | Art Direction |
| Writing | Kyle Gass | Writer |
| Camera | Robert Brinkmann | Director of Photography |
| Writing | Jack Black | Writer |
| Art | Martin Whist | Production Design |
| Writing | Liam Lynch | Writer |
| Sound | John King | Original Music Composer |
| Sound | Andrew Gross | Original Music Composer |
| Production | Georgia Kacandes | Executive Producer |
| Production | Cale Boyter | Executive Producer |
| Production | Toby Emmerich | Executive Producer |
| Crew | Tad Griffith | Stunt Double |
| Production | Juel Bestrop | Casting |
| Crew | Rick Avery | Stunt Coordinator |
| Crew | Brian Avery | Stunt Coordinator |
| Production | Jeanne McCarthy | Casting |
| Production | Richard Brener | Executive Producer |
| Production | Ben Stiller | Executive Producer |
| Crew | John Ashker | Stunt Double |
| Editing | Michael Hatzer | Digital Color Timer |
| Costume & Make-Up | Billy Bryan | Special Effects Makeup Artist |
| Lighting | Isaac McKee | Lighting Technician |
| Costume & Make-Up | Dayna Pink | Costume Design |
