In 1939 vernietigt de jonge professor Bruttenholm Erzsebet Ondrushko, een vampier die in het bloed baadde van onschuldige vrouwen om jong te blijven nadat ze haar ziel had verkocht aan de Koningin van de Heksen, de godin Hecate. Jaren later hoort het BPRD van een behekst huis in New York.
Nee, helaas is Hellboy Animated: Blood and Iron nog niet beschikbaar op Netflix in Nederland.
| Crew | Tad Stones | Additional Writing |
| Directing | Tad Stones | Director |
| Directing | Victor Cook | Director |
| Production | Scott Greenberg | Executive Producer |
| Writing | Mike Mignola | Characters |
| Production | Lawrence Gordon | Executive Producer |
| Production | Sidney Clifton | Executive Producer |
| Writing | Kevin Hopps | Screenplay |
| Writing | Guillermo del Toro | Creative Producer |
| Sound | Christopher Drake | Original Music Composer |
| Writing | Mike Mignola | Comic Book |
| Writing | Tad Stones | Story |
| Production | Morris Berger | Executive Producer |
| Production | Stephanie Elliott | Producer |
| Production | Lloyd Levin | Executive Producer |
| Production | Mike Richardson | Executive Producer |
| Production | Tad Stones | Supervising Producer |
| Production | Scott Hemming | Executive Producer |
| Writing | Mike Mignola | Story |
| Production | John W. Hyde | Executive Producer |
| Production | Stephen R. Brown | Executive Producer |
| Production | Mike Mignola | Consulting Producer |
| Editing | Matt Steinauer | Editor |
| Production | Michael Wolf | Executive Producer |
