In 1939 vernietigt de jonge professor Bruttenholm Erzsebet Ondrushko, een vampier die in het bloed baadde van onschuldige vrouwen om jong te blijven nadat ze haar ziel had verkocht aan de Koningin van de Heksen, de godin Hecate. Jaren later hoort het BPRD van een behekst huis in New York.
Nee, helaas is Hellboy Animated: Blood and Iron nog niet beschikbaar op Netflix in Nederland.
| Directing | Victor Cook | Director |
| Directing | Tad Stones | Director |
| Crew | Tad Stones | Additional Writing |
| Writing | Mike Mignola | Characters |
| Production | Sidney Clifton | Executive Producer |
| Production | Lawrence Gordon | Executive Producer |
| Production | Scott Greenberg | Executive Producer |
| Writing | Guillermo del Toro | Creative Producer |
| Writing | Kevin Hopps | Screenplay |
| Writing | Mike Mignola | Comic Book |
| Writing | Tad Stones | Story |
| Writing | Mike Mignola | Story |
| Production | Morris Berger | Executive Producer |
| Production | Stephen R. Brown | Executive Producer |
| Production | Stephanie Elliott | Producer |
| Production | Scott Hemming | Executive Producer |
| Production | John W. Hyde | Executive Producer |
| Production | Lloyd Levin | Executive Producer |
| Production | Mike Mignola | Consulting Producer |
| Production | Mike Richardson | Executive Producer |
| Production | Tad Stones | Supervising Producer |
| Production | Michael Wolf | Executive Producer |
| Sound | Christopher Drake | Music |
| Editing | Matt Steinauer | Editor |
