De rechtbank heeft Norman Bates, de moordenaar van zijn moeder en twee andere personen uit het eerste deel, officiëel genezen verklaard. Na 22 jaar in een psychiatrische inrichting, keert Norman terug naar het oude familiemotel. Als snel wordt het motel wederom het decor van een aantal onverklaarbare moorden.
Nee, helaas is Psycho II nog niet beschikbaar op Netflix in Nederland.
| Production | Hilton A. Green | Producer |
| Editing | Andrew London | Editor |
| Art | John W. Corso | Production Design |
| Camera | Dean Cundey | Director of Photography |
| Production | Bernard Schwartz | Executive Producer |
| Directing | Richard Franklin | Director |
| Sound | Jerry Goldsmith | Original Music Composer |
| Writing | Tom Holland | Writer |
| Writing | Robert Bloch | Characters |
| Art | Jennifer Polito | Set Decoration |
| Sound | Michael D. Wilhoit | Sound Editor |
| Production | Jackie Burch | Casting |
| Costume & Make-Up | Peter V. Saldutti | Costume Design |
| Sound | Andrew London | Sound Designer |
| Sound | Mark Server | Boom Operator |
| Sound | Anthony Milch | Sound Editor |
| Sound | Bob Newlan | Foley Editor |
| Sound | Lon Bender | Sound Editor |
| Sound | Gordon Ecker | Supervising Sound Editor |
| Sound | John Roesch | Foley Artist |
| Sound | Glenn T. Morgan | Assistant Sound Editor |
| Costume & Make-Up | Brian Wade | Makeup Effects Designer |
| Sound | James R. Alexander | Sound Mixer |
| Sound | Patrick Clark | Boom Operator |
| Sound | Randy Kelley | Sound Effects Editor |
| Costume & Make-Up | Marla Denise Schlom | Costume Design |
| Directing | Don Zepfel | First Assistant Director |
| Directing | Lisa Marmon | Second Assistant Director |
| Art | Martha Johnston | Set Designer |
| Crew | Greg C. Jensen | Special Effects |
| Crew | Bob Yerkes | Stunts |
| Camera | Raymond Stella | Camera Operator |
| Camera | Ronald Batzdorff | Still Photographer |
