DJay is een klein pooiertje uit Memphis die verwoede pogingen doet een carrière als rapper van de grond te krijgen. Hij probeert zijn debuutalbum op de markt te krijgen, met behulp van zijn vrienden uit de 'hood'. Wanneer hij hoort dat rap-superster Skinny Black de omgeving zal bezoeken, zet DJay een plannetje op poten om de aandacht van de ster te krijgen.
Nee, helaas is Hustle & Flow nog niet beschikbaar op Netflix in Nederland.
| Production | John Singleton | Producer |
| Directing | Craig Brewer | Director |
| Editing | Billy Fox | Editor |
| Camera | Amy Vincent | Director of Photography |
| Production | Stephanie Allain | Producer |
| Directing | Ilene Pickus | Script Supervisor |
| Production | Kimberly Hardin | Casting |
| Art | Keith Brian Burns | Production Design |
| Production | Dwight Williams | Executive Producer |
| Sound | Scott Bomar | Original Music Composer |
| Sound | Shie Rozow | Music Editor |
| Sound | Daniel J. Leahy | Sound Re-Recording Mixer |
| Sound | James Azizi Penny | Sound Effects Editor |
| Sound | Brian W. Jennings | Sound Designer |
| Sound | Marvin R. Morris | Music Editor |
| Costume & Make-Up | Paul A. Simmons Jr. | Costume Design |
| Production | Preston L. Holmes | Associate Producer |
| Sound | Greg Hedgepath | Supervising Sound Editor |
| Sound | Michael C. Casper | Sound Re-Recording Mixer |
| Sound | Frank Smathers | Supervising Sound Editor |
| Sound | Brian W. Jennings | Sound Effects Editor |
| Production | Betty Chin | Production Coordinator |
| Sound | Nathan Black | Boom Operator |
| Sound | Paul Stewart | Music Supervisor |
| Sound | Michael Camello | Sound Effects Editor |
| Writing | Craig Brewer | Writer |
| Sound | Fred Stafford | ADR Editor |
| Sound | Frayser Boy | Music Producer |
| Sound | Juicy J | Music Producer |
| Sound | DJ Paul | Music Producer |
| Sound | Stephanie Flack | Dialogue Editor |
| Sound | Bobbi Banks | Supervising ADR Editor |
| Sound | Susan Kurtz | Dialogue Editor |
| Directing | Van Hayden | First Assistant Director |
| Art | Darian Corley | Property Master |
| Art | Joni Wheeler | Set Decoration |
| Art | Alexa Marino | Art Direction |
| Sound | Paul Hackner | Dialogue Editor |
| Camera | James McMillan | Key Grip |