Daphne is uitgekozen om de hoofdrol te spelen in een vampierfilm en haar vrienden van het onderzoeksteam zijn erg blij met haar succes. Zodra het filmen begint, wordt echter duidelijk dat er onder de acteurs een echte vampier zit die vastbesloten is de film te verpesten. Dit zet Scooby Doo en zijn vrienden ertoe aan een gewaagd onderzoek te beginnen, gericht op het vinden van de vampier en het neutraliseren ervan voordat het te laat is.
Nee, helaas is Scooby-Doo! Music of the Vampire nog niet beschikbaar op Netflix in Nederland.
| Directing | David Block | Director |
| Editing | Kyle Stafford | Editor |
| Production | Alan Burnett | Co-Producer |
| Sound | Patrick J. Foley | Dialogue Editor |
| Editing | Christopher D. Lozinski | Online Editor |
| Sound | Niki Sherrod | Other |
| Sound | Kelly Ann Foley | ADR Editor |
| Sound | Michael Garcia | Dialogue Editor |
| Production | Jay Bastian | Executive In Charge Of Production |
| Crew | Ken Spears | Thanks |
| Crew | Scott Shinick | Post-Production Manager |
| Crew | Damon Criswell | Additional Music |
| Sound | Kelly Ann Foley | Dialogue Editor |
| Sound | Patrick J. Foley | ADR Editor |
| Art | Ted Blackman | Art Direction |
| Crew | Joe Ruby | Thanks |
| Production | A.J. Vargas | Associate Producer |
| Production | Sam Register | Executive Producer |
| Editing | Steven White | Online Editor |
| Sound | Mark A. Keatts | Supervising Dialogue Editor |
| Sound | Michael Garcia | ADR Editor |
| Production | Liz Carroll | Administration |
| Production | Ed Adams | Production Manager |
| Production | Jeff Prezenkowski | Executive In Charge Of Production |
| Production | Bobbie Page | Production Supervisor |
| Production | Spike Brandt | Producer |
| Production | Tony Cervone | Producer |
| Sound | Andy Sturmer | Original Music Composer |
| Writing | Tom Sheppard | Writer |
| Production | Andrea Romano | Casting |
| Sound | Mark A. Keatts | Supervising ADR Editor |
| Production | Jeff Prezenkowski | Production Manager |
| Art | Eric Semones | Art Direction |
| Production | David Vasquez | Production Manager |
| Visual Effects | Matthew Girardi | Visual Effects |
| Production | Jay Bastian | Production Manager |