In dit vervolg creëert de boze tovenaar Gargamel een paar ondeugende Smurf-achtige wezens, waarmee hij de magische krachten van de Smurfen hoopt te kunnen benutten. Maar als hij er achter komt dat alleen een echte Smurf hem kan geven wat hij wil en alleen een geheime spreuk die Smurfin weet de wezens kan veranderen in echte smurfen, kidnapt Gargamel Smurfin.
Nee, helaas is De Smurfen 2 nog niet beschikbaar op Netflix in Nederland.
| Visual Effects | Michael Parks | Animation |
| Visual Effects | Juan Miguel Vadell | Animation |
| Crew | Wayne Jaworskyj | Compositors |
| Crew | Jacob Jared Jones | Compositors |
| Crew | Jessica Wolff | Compositors |
| Visual Effects | Dixie Pizani | Animation |
| Visual Effects | Aaron Williams | VFX Artist |
| Crew | David Settlow | Visual Effects Design Consultant |
| Crew | Elizabeth McClurg | Compositors |
| Crew | Joo-Hwan Park | Compositors |
| Writing | Karey Kirkpatrick | Screenplay |
| Writing | David Ronn | Story |
| Writing | David N. Weiss | Story |
| Writing | David N. Weiss | Screenplay |
| Writing | Jay Scherick | Story |
| Production | Benita Allen | Co-Producer |
| Writing | J. David Stem | Story |
| Writing | Jay Scherick | Screenplay |
| Production | Ben Haber | Executive Producer |
| Writing | David Ronn | Screenplay |
| Production | Raphaël Benoliel | Co-Producer |
| Production | Hendrik Coysman | Co-Producer |
| Production | Véronique Culliford | Co-Producer |
| Writing | Peyo | Characters |
| Directing | Carole Schmidlin Blanchard | Crowd Assistant Director |
| Production | Paul Neesan | Executive Producer |
| Art | Frédérique Bolté | Set Decoration |
| Production | Jordan Kerner | Producer |
| Production | Juliette Ménager | Casting |
| Art | Marie-Soleil Dénommé | Set Decoration |
| Costume & Make-Up | Véronique Marchessault | Costume Design |
| Directing | Sarah Heitz de Chabaneix | Additional Third Assistant Director |
| Production | Sabrina Plisco | Associate Producer |
| Art | Benoît Tetelin | Set Decoration |
| Production | Michael Killoren | Production Manager |
| Directing | G. A. Aguilar | Second Unit Director |
| Directing | Dominic Gaglione D'Amico | Third Assistant Director |
| Directing | Silver Butler | Second Second Assistant Director |
| Directing | Martin Doepner | Additional Third Assistant Director |
| Production | Ezra Swerdlow | Executive Producer |
| Production | Nancy Honeycutt | Production Supervisor |
| Directing | Yannick Fauchier | Second Assistant Director |
| Production | Andrea Kenyon | Casting |
| Production | David Rubin | Casting |
| Costume & Make-Up | Geoffroy Gosselin | On Set Dresser |
| Production | Matthieu Rubin | Unit Production Manager |
| Directing | Gabrielle Hanne | Second Assistant Director |
| Editing | Sabrina Plisco | Editor |
| Art | David Gaucher | Art Direction |
| Directing | Anaïs Barrat | Crowd Assistant Director |
| Directing | Maxence Paris | Crowd Assistant Director |
| Crew | David E. Hall | Post Production Supervisor |
| Directing | Yann Le Boucher | Third Assistant Director |
| Art | Michele Laliberte | Supervising Art Director |
| Directing | Benita Allen | First Assistant Director |
| Camera | Phil Meheux | Director of Photography |
| Art | Bill Boes | Production Design |
| Production | Daniel Carbo | Production Manager |
| Directing | Ariane Côté-Chénier | Additional Third Assistant Director |
| Production | Maricel Pagulayan | Associate Producer |
| Art | Pascale Deschênes | Set Decoration |
| Production | Paul Boutin | Unit Manager |
| Directing | Felix Baudouin | Second Assistant Director |
| Directing | Serena Yang | Second Unit Director |
| Art | David Laramy | Set Decoration |
| Costume & Make-Up | Rita Ryack | Costume Design |
| Production | Lea Lambert | Production Manager |
| Art | Emma Pucci | Art Direction |
| Directing | Antoine Desanti | Assistant Director |
| Art | Vincent Gingras-Liberali | Art Direction |
| Directing | Raja Gosnell | Director |
| Crew | Alain Moussi | Stunts |
| Production | Randi Wells | Casting |
| Editing | Jered Zalman | Assistant Editor |
| Sound | Becky G | Songs |
| Sound | Austin Mahone | Songs |
| Writing | J. David Stem | Screenplay |
| Directing | Sinan Saber | Third Assistant Director |
| Writing | Peyo | Comic Book |
| Sound | Heitor Pereira | Original Music Composer |
| Costume & Make-Up | Todd Tucker | Makeup Department Head |
| Crew | G. A. Aguilar | Stunt Coordinator |
| Directing | Sean Dwyer | First Assistant Director |
| Visual Effects | Matt Salkin | Visual Effects Coordinator |
