In de straten van New Orleans begint het nieuws te verspreiden over een mysterieuze nieuwe pil die superkrachten ontgrendelt die uniek zijn voor elke gebruiker. De vangst: u weet niet wat er zal gebeuren totdat u het neemt. Terwijl sommigen een kogelvrije huid, onzichtbaarheid en superkracht ontwikkelen, vertonen anderen een dodelijkere reactie. Maar wanneer de pil de criminaliteit in de stad tot gevaarlijke niveaus doet escaleren, werkt een lokale agent (Joseph Gordon-Levitt) samen met een tienerdealer (Dominique Fishback) en een voormalige soldaat die wordt gevoed door een geheime vendetta (Jamie Foxx) om de macht met macht en het risico nemen om de pil te nemen om de groep die verantwoordelijk is voor het maken ervan op te sporen en te stoppen.
| Crew | Janelle Beaudry | Stunts |
| Visual Effects | Jared Hasselbach | VFX Artist |
| Crew | Vanessa Motta | Stunt Double |
| Production | Tyler Hohmann | Assistant Location Manager |
| Crew | Taryn Terrell | Stunts |
| Visual Effects | Wakako Sekine | Compositing Artist |
| Visual Effects | Olivier Jobin | Visual Effects Coordinator |
| Directing | Ariel Schulman | Director |
| Directing | Henry Joost | Director |
| Production | Eric Newman | Producer |
| Production | Bryan Unkeless | Producer |
| Writing | Mattson Tomlin | Writer |
| Camera | Michael Simmonds | Director of Photography |
| Production | Orlee-Rose Strauss | Executive Producer |
| Production | Ray Angelic | Executive Producer |
| Production | John Papsidera | Casting |
| Sound | Joseph Trapanese | Original Music Composer |
| Editing | Jeff McEvoy | Editor |
| Art | Naomi Shohan | Production Design |
| Art | Tom Frohling | Art Direction |
| Art | Matthew Gatlin | Art Direction |
| Art | Jonathan Opgenhaffen | Art Direction |
| Art | John Sanchez | Art Direction |
| Art | Cynthia La Jeunesse | Set Decoration |
| Costume & Make-Up | Sharen Davis | Costume Design |
| Costume & Make-Up | Anthony Canonica | Special Effects Makeup Artist |
| Costume & Make-Up | Daina Daigle | Hair Department Head |
| Costume & Make-Up | Lindsay Gelfand | Prosthetic Makeup Artist |
| Costume & Make-Up | Sherri Hamilton | Key Hair Stylist |
| Costume & Make-Up | Crystal Jurado | Special Effects Key Makeup Artist |
| Costume & Make-Up | Stacy Kelly | Makeup Department Head |
| Costume & Make-Up | Dee Leveque | Hairstylist |
| Costume & Make-Up | Ashley Levy | Makeup Department Head |
| Costume & Make-Up | Sherri Hamilton | Hair Department Head |
| Costume & Make-Up | Göran Lundström | Prosthetic Makeup Artist |
| Costume & Make-Up | Mike Marino | Makeup Effects Designer |
| Costume & Make-Up | Lana Mora | Makeup Artist |
| Costume & Make-Up | Stacey Perry | Makeup Artist |
| Costume & Make-Up | Ignacia Soto-Aguilar | Key Makeup Artist |
| Costume & Make-Up | Adam Walls | Key Makeup Artist |
| Crew | Luca Borghese | Post Production Supervisor |
| Production | Michael B. Johnson | Production Supervisor |
| Production | Michael Morgan | Post Production Producer |
| Production | Ian Watermeier | Unit Production Manager |
| Crew | Joe Nin Williams | Stunts |
| Crew | Minerva Adams | Stunt Double |
| Crew | Kenny Bartram | Stunt Double |
| Crew | Sadiqua Bynum | Stunt Double |
| Crew | Gui DaSilva-Greene | Stunt Double |
| Crew | Liam Day | Stunt Double |
| Crew | Cory DeMeyers | Stunt Coordinator |
| Crew | Michael Endoso | Stunt Double |
| Crew | Timothy Eulich | Stunt Double |
| Art | Thomas du Crest | Concept Artist |
| Visual Effects | Lilia Collar | Digital Compositor |
| Art | Teddy Blanks | Main Title Designer |
| Visual Effects | Matthew Twyford | Visual Effects Supervisor |
| Visual Effects | Patrick Allen | Visual Effects Coordinator |
| Visual Effects | Joao Sita | Visual Effects Supervisor |
| Visual Effects | Ivan Moran | Visual Effects Supervisor |
