John Rambo is met pensioen en woont op een boerderij in de Verenigde Staten. Op een dag hoort hij van Maria, een oude familievriendin en vastgoedmanager, dat zijn dochter is ontvoerd door een Mexicaans drugskartel. Al snel komt John terecht in de gewelddadige wereld van de sekshandel. Hij werkt samen met een journalist, wiens halfzus ook is ontvoerd, en moet al zijn vaardigheden inzetten om de meisjes te redden en een kwaadaardige misdaadbaas neer te halen.
Nee, helaas is Rambo: Last Blood nog niet beschikbaar op Netflix in Nederland.
| Crew | Dessy Slavova | Stunt Double |
| Crew | Radka Petkova | Stunts |
| Writing | Matthew Cirulnick | Screenplay |
| Writing | Sylvester Stallone | Screenplay |
| Production | Avi Lerner | Producer |
| Production | Kevin King Templeton | Producer |
| Production | Ariel Vromen | Executive Producer |
| Production | Christa Campbell | Executive Producer |
| Production | Lati Grobman | Executive Producer |
| Directing | Adrian Grünberg | Director |
| Art | Franco-Giacomo Carbone | Production Design |
| Art | David Temprano | Art Direction |
| Art | Eduardo Hidalgo Jr. | Art Direction |
| Sound | Ryan Nowak | Sound Designer |
| Sound | Vladimir Kaloyanov | Sound Mixer |
| Sound | Kiril Kaloyanov | Boom Operator |
| Writing | David Morrell | Characters |
| Sound | Brian Tyler | Original Music Composer |
| Camera | Brendan Galvin | Director of Photography |
| Editing | Carsten Kurpanek | Editor |
| Editing | Todd E. Miller | Editor |
| Production | Yariv Lerner | Producer |
| Production | Les Weldon | Producer |
| Production | Samuel Hadida | Co-Executive Producer |
| Production | Victor Hadida | Co-Executive Producer |
| Production | Louis Arriola | Executive Producer |
| Production | Boaz Davidson | Executive Producer |
| Production | Jeffrey Greenstein | Executive Producer |
| Production | Jonathan Yunger | Executive Producer |
| Production | Jeff Gum | Executive Producer |
| Production | Robert Van Norden | Executive Producer |
| Production | Matthew O'Toole | Executive Producer |
| Production | Liu Rong | Executive Producer |
| Production | Zhang Qun | Executive Producer |
| Production | Allen Dam | Executive Producer |
| Production | Jiewen Tan | Executive Producer |
| Production | Elijah Long | Co-Executive Producer |
| Production | Damaine Radcliff | Co-Executive Producer |
| Costume & Make-Up | Cristina Sopeña | Costume Designer |
| Production | Carla Hool | Casting |
| Production | Valentin Dimitrov | Line Producer |
| Production | Vessela Bannzurkova | Unit Production Manager |
| Production | Alberto Poveda Rey | Unit Production Manager |
| Directing | Charlie Watson | First Assistant Director |
| Directing | Paul Taylor | Second Assistant Director |
| Crew | Diyan Hristov | Stunt Coordinator |
| Crew | Cuco Usín | Stunt Coordinator |
| Crew | Georgi Manchev | Fight Choreographer |
| Production | Lonnie Ramati | Co-Executive Producer |
| Directing | Maralyn Causley | Script Supervisor |
| Lighting | Konstantin Vladimirov | Gaffer |
| Camera | Miroslav Borisov | Key Grip |
| Sound | Boris Tanchev | Boom Operator |
| Art | Kess Bonnet | Supervising Art Director |
| Art | Emil Gigov | Art Direction |
| Art | Valentina Mladenova | Set Decoration |
| Art | Nieves Monterde | Set Decoration |
| Art | Dirk Buchmann | Property Master |
| Visual Effects | Richard Van Den Bergh | Special Effects Supervisor |
| Visual Effects | Pau Costa | Special Effects Supervisor |
| Directing | Vern Nobles | Second Unit Director |
| Sound | Kris Casavant | Supervising Sound Editor |
| Sound | Tapio Liukkonen | Foley Artist |
| Visual Effects | Aleksander Aleksiev | Visual Effects Supervisor |
| Production | Steven Paul | Producer |
| Camera | Don Cherel | Camera Operator |
| Camera | Des Whelan | Camera Operator |
| Camera | Dawid Pietkiewicz | Camera Operator |
| Camera | Ivan Vatsov | Camera Operator |
| Camera | Rafael Rodriguez Lamas | Digital Imaging Technician |
| Camera | Ivo Velkov | Digital Imaging Technician |
| Camera | Dimitar Krustev | Drone Pilot |
| Lighting | Ognian Atanasov | Electrician |
| Lighting | Eduardo Camprubí | Electrician |
| Lighting | Héctor Gabriel García | Electrician |
| Lighting | Sven Vohser | Electrician |
| Camera | Borislav Belberov | First Assistant Camera |
| Camera | Ivana Vladić | First Assistant Camera |
| Camera | Ivailo Tzvetkov | First Assistant "A" Camera |
| Camera | Lyubomir Somov | First Assistant "A" Camera |
| Camera | Paula Nenova | First Assistant "B" Camera |
| Camera | Ivelin Metodiev | First Assistant "C" Camera |
| Camera | Héctor Quintero Domínguez | Focus Puller |
| Camera | Luis Cesar Izquierdo | Focus Puller |
| Camera | Desislav Dimitrov | Grip |
| Camera | Biser Rulev | Grip |
| Camera | Valentin Stanimirov | Grip |
| Camera | Aleksandar Ribarski | Grip |
| Crew | Vern Nobles | Second Unit Cinematographer |
| Camera | Dave Isern | Steadicam Operator |
| Camera | Simon Varsano | Still Photographer |
| Costume & Make-Up | Tiptalee Chanaputtakun | Hairstylist |
| Costume & Make-Up | Daniela Avramova | Key Makeup Artist |
| Costume & Make-Up | Yurena Cazorla | Makeup Artist |
| Costume & Make-Up | Desislava Manasieva | Makeup Artist |
| Costume & Make-Up | Ralitsa Roth | Makeup Artist |
| Costume & Make-Up | Fionagh Cush | Makeup Artist |
| Costume & Make-Up | Stephen Prouty | Prosthetic Designer |
| Production | Mark Sussman | ADR Voice Casting |
| Production | Natalie Ballesteros | Casting Associate |
| Production | Eliseo Ruiz | Casting Associate |
| Production | Patricia Amor | Casting Associate |
| Production | Camilla-Valentine Isola | Casting |
| Production | Hrista Ilieva | Extras Casting |
| Production | Cristina Santacreu | Extras Casting Assistant |
| Costume & Make-Up | Fernando García Brea | Assistant Costume Designer |
| Costume & Make-Up | Eva Fervenza | Costume Supervisor |
| Costume & Make-Up | Jasmina Vasileva | Costume Supervisor |
| Costume & Make-Up | Paula Barroso | Costumer |
| Costume & Make-Up | Gara Hamad | Costumer |
| Costume & Make-Up | Katarina Pavlova | Costumer |
| Costume & Make-Up | Nuria Barrio | Set Costumer |
| Visual Effects | Magnus Olsson | 3D Artist |
| Visual Effects | A. Martín Puentes | Animation Supervisor |
| Visual Effects | David Andreu | Animation |
| Crew | Diego Gortázar | CG Supervisor |
| Visual Effects | Dragostin Valev | Compositing Supervisor |
| Lighting | Daniel Arenas Cortes | Lighting Artist |
| Visual Effects | Helena Holmes | Special Effects Supervisor |
| Visual Effects | Aleksey Hrzhehorzhevskyi | Visual Effects Coordinator |
| Visual Effects | Julia Manolova | Visual Effects Coordinator |
| Visual Effects | Svetoslav Mitev | Visual Effects Coordinator |
| Visual Effects | Alice Olson-Coons | Visual Effects Coordinator |
| Visual Effects | Danail Hadzhiyski | Visual Effects Producer |
| Visual Effects | Łukasz Kołtunowicz | Visual Effects Producer |
| Visual Effects | Pedro Domingo Luque | Visual Effects Producer |
| Visual Effects | Andres Mas | Visual Effects Production Assistant |
| Visual Effects | Anna Rovira Macià | Visual Effects Production Manager |
| Visual Effects | Kristian Talajic | Visual Effects Supervisor |
| Visual Effects | Alexander Kadim | Visual Effects Supervisor |
| Art | Tatiana Urquiza | Art Department Assistant |
| Art | Joseph Díaz | Concept Artist |
| Art | Pavlina Petrova | Concept Artist |
| Art | Evgeni Yordanov | Construction Manager |
| Art | Orlando Harris | Graphic Designer |
| Art | Anna Hadzhieva | Set Decorating Coordinator |
| Art | Nieves Monterde | Set Designer |
| Art | Nikolai Nikolov | Set Designer |
| Art | Marimar Lara | Standby Painter |
| Art | Cristina Acuña | Standby Painter |
| Art | Neil D'Monte | Storyboard Artist |
| Art | Krista Vacheva | Storyboard Artist |
| Editing | Ivan Todorov Ivanov | Assistant Editor |
| Editing | Bradley Greer | Digital Intermediate Colorist |
| Editing | Nedelko Tudzharov | First Assistant Editor |
| Editing | Damian F. Gomez | First Assistant Editor |
| Writing | Dan Gordon | Screenstory |
| Writing | Sylvester Stallone | Screenstory |
| Crew | Max Kraus | Stunts |
| Crew | Dian Hristov | Stunt Coordinator |
