Adam is een 27-jarige schrijver van radioprogramma's. Hij wordt gediagnosticeerd met een zeldzame vorm van kanker in zijn wervelkolom. Gezien zijn jonge leeftijd en gezonde levensstijl kan Adam moeilijk geloven dat dit met hem gebeurt.
Nee, helaas is 50/50 nog niet beschikbaar op Netflix in Nederland.
| Directing | Jonathan Levine | Director |
| Writing | Will Reiser | Writer |
| Production | Evan Goldberg | Producer |
| Production | Seth Rogen | Producer |
| Production | Francine Maisler | Casting |
| Production | Nathan Kahane | Executive Producer |
| Sound | Michael Giacchino | Original Music Composer |
| Camera | Terry Stacey | Director of Photography |
| Editing | Zene Baker | Editor |
| Art | Annie Spitz | Production Design |
| Art | Ross Dempster | Art Direction |
| Art | Shane Vieau | Set Decoration |
| Costume & Make-Up | Monica Huppert | Makeup Department Head |
| Costume & Make-Up | Debra Wiebe | Hair Department Head |
| Costume & Make-Up | Carla Hetland | Costume Design |
| Sound | Gabe Hilfer | Music Supervisor |
| Sound | Jim Black | Music Supervisor |
| Sound | Stephen M. Davis | Music Editor |
| Directing | Stephanie Rossel | Script Supervisor |
| Camera | Chris Helcermanas-Benge | Still Photographer |
| Lighting | Stuart Haggerty | Gaffer |
| Lighting | Sean Oxenbury | Rigging Gaffer |
| Crew | Scott J. Ateah | Stunt Coordinator |
| Visual Effects | Dottie Starling | Visual Effects Supervisor |
| Production | Will Reiser | Executive Producer |
| Costume & Make-Up | Stacey Butterworth | Wigmaker |
| Crew | Nancy Kirhoffer | Post Production Supervisor |
| Production | Paul Lukaitis | Unit Production Manager |
| Directing | Iris Torres | Assistant Director |
| Crew | Jak Osmond | Special Effects Coordinator |
| Visual Effects | Elbert Irving IV | Visual Effects Coordinator |
| Visual Effects | Lauren Ritchie | Visual Effects Producer |
| Crew | Ed Anders | Stunts |
| Crew | Brett Armstrong | Stunts |
| Crew | Dan Redford | Stunts |
| Crew | Owen Walstrom | Stunts |
| Crew | Uwe Boll | Thanks |
| Crew | James L. Brooks | Thanks |
| Crew | James McAvoy | Thanks |
| Crew | Lorraine Jamison | Unit Publicist |
| Editing | George Chavez | Color Timer |
| Editing | Michael A. Webber | Assistant Editor |
| Camera | Kieran Humphries | First Assistant Camera |
| Lighting | Niall Fraser | Best Boy Electric |
| Production | Nicole Brown | Co-Producer |
| Production | Ben Karlin | Producer |
| Production | Kelli Konop | Co-Producer |
| Production | Tendo Nagenda | Co-Producer |
| Production | Shawn Williamson | Line Producer |
