Dr. Sloan vermoedt dat een oude vlam van hem, de beroemde hartchirurge Rachel Walters, verantwoordelijk is voor de moord op een senator. Samen met twee collega's en zijn eigen zoon Steve gaat hij op onderzoek uit.
Nee, helaas is Diagnosis Murder: A Twist of the Knife nog niet beschikbaar op Netflix in Nederland.
| Directing | Jerry London | Director |
| Production | Barry Steinberg | Unit Production Manager |
| Writing | Gerry Conway | Writer |
| Production | Joyce Burditt | Supervising Producer |
| Art | Laurie Holsgrove | Set Decoration |
| Production | Fred Silverman | Producer |
| Crew | Robert Seaman | Cinematography |
| Costume & Make-Up | Patti Dallas | Makeup Artist |
| Production | Barry Steinberg | Producer |
| Production | Maureen A. Arata | Casting |
| Art | Paul Staheli | Production Design |
| Costume & Make-Up | Judith Scheurwater | Costume Design |
| Production | Dean Hargrove | Producer |
| Costume & Make-Up | Mary L. Mastro | Hair Designer |
| Sound | Dick DeBenedictis | Music |
| Writing | William Read Woodfield | Writer |
| Costume & Make-Up | Stacy Halax | Makeup Artist |
| Production | Paul Mason | Executive In Charge Of Production |
