Dr. Sloan vermoedt dat een oude vlam van hem, de beroemde hartchirurge Rachel Walters, verantwoordelijk is voor de moord op een senator. Samen met twee collega's en zijn eigen zoon Steve gaat hij op onderzoek uit.
Nee, helaas is Diagnosis Murder: A Twist of the Knife nog niet beschikbaar op Netflix in Nederland.
| Directing | Jerry London | Director |
| Writing | Gerry Conway | Writer |
| Writing | William Read Woodfield | Writer |
| Production | Joyce Burditt | Supervising Producer |
| Production | Dean Hargrove | Producer |
| Production | Fred Silverman | Producer |
| Production | Barry Steinberg | Producer |
| Sound | Dick DeBenedictis | Music |
| Crew | Robert Seaman | Cinematography |
| Production | Maureen A. Arata | Casting |
| Art | Paul Staheli | Production Design |
| Art | Laurie Holsgrove | Set Decoration |
| Costume & Make-Up | Judith Scheurwater | Costume Design |
| Costume & Make-Up | Patti Dallas | Makeup Artist |
| Costume & Make-Up | Stacy Halax | Makeup Artist |
| Costume & Make-Up | Mary L. Hart-Mastro | Hair Designer |
| Production | Barry Steinberg | Unit Production Manager |
| Production | Paul Mason | Executive In Charge Of Production |
