Marie is een vampier met een geweten, die op zoek is naar seks en bloed. Zij besluit haar werkterrein te verleggen naar Pittsburgh, waar de maffia heerst. Als ze een hapje neemt van Sal Macelli, een hoge gangsterbaas, beginnen de problemen. Als zij er niet in slaagt om haar slachtoffers uit te schakelen, worden ze zelf vampieren, en omdat de maffiabaas het overleeft dreigen er grote problemen. Ondertussen wordt ze verliefd op de politieagent die achter de maffiabaas aanzit...
Nee, helaas is Innocent Blood nog niet beschikbaar op Netflix in Nederland.
| Directing | John Landis | Director |
| Writing | Michael Wolk | Screenplay |
| Sound | Ira Newborn | Original Music Composer |
| Production | Leslie Belzberg | Producer |
| Production | Lee Rich | Producer |
| Camera | Mac Ahlberg | Director of Photography |
| Editing | Dale Beldin | Editor |
| Crew | Glory Fioramonti | Stunts |
| Crew | Tom Elliott | Stunts |
| Production | Jonathan Sheinberg | Executive Producer |
| Production | Michael Wolk | Associate Producer |
| Art | Richard Sawyer | Production Design |
| Art | Martin Charles | Art Direction |
| Art | Peg Cummings | Set Decoration |
| Costume & Make-Up | Deborah Nadoolman Landis | Costume Design |
| Costume & Make-Up | Ron Berkeley | Makeup Artist |
| Production | Janet L. Wattles | Production Supervisor |
| Production | Paul Deason | Unit Production Manager |
| Directing | Rosemary C. Cremona | Second Assistant Director |
| Directing | Nicholas Mastandrea | First Assistant Director |
| Directing | Susan Pickett | Second Second Assistant Director |
| Art | Karl J. Martin | Set Designer |
| Art | Jim Schneider | Lead Set Dresser |
| Crew | Marian Green | Stunts |
| Crew | Bill Corso | Makeup Effects |
| Crew | Jeannie Epper | Stunts |
| Crew | Bob Minor | Stunts |
| Crew | Kurt Bryant | Stunts |
| Crew | Joni Avery | Stunt Double |
| Crew | Spiro Razatos | Stunts |
| Crew | Troy Brown | Stunts |
| Crew | Merritt Yohnka | Stunts |
| Crew | Andy Gill | Stunts |
| Crew | Charles Croughwell | Stunts |
| Crew | Syd Dutton | Special Effects |
| Crew | Jeff Cadiente | Stunts |
| Crew | Monty Cox | Stunts |
| Crew | Clay Boss | Stunts |
| Crew | Mike De Luna | Stunts |
| Crew | Richard Epper | Stunts |
| Crew | Steve Hulin | Stunts |
| Crew | Andreé Gibbs | Stunts |
| Crew | Keii Johnston | Stunts |
| Crew | Bill McIntosh | Stunts |
| Crew | Brad Orrison | Stunts |
| Crew | Buck McDancer | Stunts |
| Crew | Don Pulford | Stunts |
| Crew | Mark Orrison | Stunts |
| Crew | Branscombe Richmond | Stunts |
| Crew | Michael J. Sarna | Stunts |
| Art | Penelope Gottlieb | Title Designer |
| Crew | Scott Coulter | Special Effects |
| Production | Sharon Howard-Field | Casting |
| Production | Donna M. Belajac | Additional Casting |
| Sound | Doug Hemphill | Sound Re-Recording Mixer |
| Sound | Paul Massey | Sound Re-Recording Mixer |
| Sound | Mark Smith | Sound Re-Recording Mixer |
| Costume & Make-Up | Steve Johnson | Special Effects Makeup Artist |
