Tijdens de Middeleeuwen zijn de Lycans de slaven van de aristocratische vampieren. Lucian (Michael Sheen), één van de Lycans, zet de weerwolven op om te strijden tegen Viktor (Bill Nighy), de koning der vampieren. In zijn strijd voor hun vrijheid wordt Lucian vergezeld door zijn geheime geliefde Sonja (Rhona Mitra). Haar aanwezigheid zorgt voor de nodige veranderingen in de plannen van Lucian.
Nee, helaas is Underworld: Rise of the Lycans nog niet beschikbaar op Netflix in Nederland.
| Directing | Patrick Tatopoulos | Director |
| Writing | Kevin Grevioux | Characters |
| Writing | Len Wiseman | Characters |
| Production | Beth DePatie | Executive Producer |
| Production | Len Wiseman | Producer |
| Production | Gary Lucchesi | Producer |
| Camera | Ross Emery | Director of Photography |
| Art | Dan Hennah | Production Design |
| Art | Brendan Heffernan | Art Direction |
| Art | Gary Mackay | Art Direction |
| Costume & Make-Up | Jane Holland | Costume Design |
| Crew | Jeff Flitton | Makeup Effects |
| Costume & Make-Up | Connie Grayson Criswell | Hairstylist |
| Lighting | Jamie Couper | Lighting Technician |
| Lighting | John Enright | Best Boy Electric |
| Lighting | Sean O'Neill | Gaffer |
| Costume & Make-Up | Sian Evans | Costume Supervisor |
| Writing | Danny McBride | Characters |
| Writing | Danny McBride | Screenplay |
| Production | Liz Mullane | Casting |
| Crew | Sean Button | Stunts |
| Crew | Hauk Olafsson | Special Effects |
| Crew | Tim Rigby | Stunts |
| Production | Tom Rosenberg | Producer |
| Production | Kevin Grevioux | Co-Producer |
| Production | David Kern | Co-Producer |
| Production | James McQuaide | Executive Producer |
| Production | Eric Reid | Executive Producer |
| Production | Skip Williamson | Executive Producer |
| Production | Henry Winterstern | Executive Producer |
| Production | Richard S. Wright | Producer |
| Editing | Peter Amundson | Editor |
| Editing | Eric Potter | Editor |
| Writing | Dirk Blackman | Screenplay |
| Writing | Howard McCain | Screenplay |
| Writing | Danny McBride | Story |
| Writing | Len Wiseman | Story |
| Crew | Dayna Grant | Stunt Double |
| Crew | Dayna Grant | Stunts |
| Crew | Kee Kee Buckley | Thanks |
| Writing | Robert Orr | Writer |
| Visual Effects | Christopher Warren | VFX Director of Photography |
| Sound | Paul Haslinger | Music |
| Visual Effects | Patrick Tatopoulos | Creature Design |
