De succesvolle meesterspionnen werken niet meer. De nieuwste gadgets zijn nu voor anderen tot....Juni een spectaculaire opdracht krijgt, waar hij geen nee tegen kan zeggen. Zijn zus Carmen zit opgesloten in een levensgevaarlijk computerspel, gemaakt door de verschrikkelijk kwaadaardige 'Toymaker'. Juni is de enige die haar zou kunnen bevrijden. In een razendsnelle race tegen de klok moet Juni al zijn talent, vernuft en beschikbare hightech snufjes inzetten. Extra hulp is noodzakelijk. Zal hij op tijd zijn om zijn zus te bevrijden?
Nee, helaas is Spy Kids 3-D: Game Over nog niet beschikbaar op Netflix in Nederland.
| Production | Harvey Weinstein | Executive Producer |
| Production | Elizabeth Avellan | Producer |
| Sound | Rebecca Rodriguez | Original Music Composer |
| Sound | Robert Rodriguez | Original Music Composer |
| Directing | Robert Rodriguez | Director |
| Writing | Robert Rodriguez | Screenplay |
| Production | Bob Weinstein | Executive Producer |
| Camera | Robert Rodriguez | Director of Photography |
| Production | Robert Rodriguez | Producer |
| Editing | Robert Rodriguez | Editor |
| Crew | Jeff 'JJ' Dashnaw | Stunt Coordinator |
| Production | Bill Scott | Line Producer |
| Production | Mary Vernieu | Casting |
| Production | Bill Scott | Unit Production Manager |
| Directing | Brian Bettwy | First Assistant Director |
| Directing | Vincent Palmo Jr. | Second Assistant Director |
| Visual Effects | Robert Rodriguez | Visual Effects Supervisor |
| Visual Effects | Daniel Leduc | Visual Effects Supervisor |
| Crew | Brian McNulty | Post Production Supervisor |
| Visual Effects | Brian McNulty | Visual Effects Producer |
| Visual Effects | Keefe Boerner | Visual Effects Coordinator |
| Crew | Ethan Maniquis | Visual Effects Editor |
| Editing | Jay Mahavier | First Assistant Editor |
| Crew | J.J. Dashnaw | Stunts |
| Crew | Chad Dashnaw | Stunts |
| Crew | Josh Kemble | Stunts |
| Crew | Tony Lee Boggs | Stunts |
| Crew | Shawn Robinson | Stunts |
| Art | Jeanette Scott | Art Direction |
| Art | Jeanette Scott | Set Dresser |
| Art | Ronn Basquette | Set Designer |
| Art | Marc Baird | Storyboard Artist |
| Art | Debbie Cortez Haber | Art Department Coordinator |
| Directing | Romy Stevenson | Second Second Assistant Director |
| Costume & Make-Up | Nina Proctor | Costume Design |
| Costume & Make-Up | Nina Proctor | Costume Supervisor |
| Costume & Make-Up | Mitzie Corbin | Key Set Costumer |
| Costume & Make-Up | Natalie Flores | Costume Supervisor |
| Costume & Make-Up | Vanessa Nirode | Set Costumer |
| Costume & Make-Up | Claire Nicholas | Set Costumer |
| Costume & Make-Up | M. Caroline Pruet | Set Costumer |
| Costume & Make-Up | Crystal Falkner-Paysse | Costume Assistant |
| Costume & Make-Up | Esther Mary Marquis | Seamstress |
| Costume & Make-Up | Lucy Moncado | Seamstress |
| Costume & Make-Up | Rebecca M. Skelton | Seamstress |
| Costume & Make-Up | Erin Randall | Costume Assistant |
| Costume & Make-Up | Ermahn Ospina | Makeup Department Head |
| Costume & Make-Up | Melissa Forney | Hair Department Head |
| Costume & Make-Up | Joe Rivera | Makeup & Hair Assistant |
| Camera | Jimmy Lindsey | Camera Operator |
| Camera | Sebastian Vega | First Assistant Camera |
| Camera | Joe Vasquez | Second Assistant Camera |
| Directing | Monika Petrillo | Script Supervisor |
| Camera | Rico Torres | Still Photographer |
| Sound | Stacy Brownrigg | Production Sound Mixer |
| Sound | Thadd Day | Boom Operator |
| Lighting | John 'Fest' Sandau | Chief Lighting Technician |
| Lighting | Todd Smiley | Best Boy Electric |
| Lighting | Buzzy Burwell | Electrician |
| Lighting | Scott Conn | Electrician |
| Lighting | Matt Fliehler | Electrician |
| Lighting | Robert Janecka | Electrician |
| Camera | Richard Ball | Key Grip |
| Camera | Sean Wright | Best Boy Grip |
| Camera | Mike Sheeren | Dolly Grip |
| Camera | Cynthia Bystrak | Grip |
| Camera | Chris Hamala | Grip |
| Camera | Steve Urban | Grip |
| Crew | Corey Pritchett | Special Effects Coordinator |
| Visual Effects | Jason Gustafson | Special Effects Supervisor |
| Production | Brian Bruskrud | Production Accountant |
| Production | Jourdan Henderson | Production Secretary |
| Production | Cynthia Streit | Production Coordinator |
| Production | Todd Green | Assistant Production Coordinator |
| Production | Sandra Condito | Publicist |
| Production | Mylan Stepanovich | First Assistant Accountant |
| Production | Dawn Robinette | Payroll Accountant |
| Production | Whitney Miller | Post Production Accountant |
| Art | David Hack | Set Decoration |
| Art | Jennifer Long | Assistant Set Decoration |
| Art | Christopher Stull | Leadman |
| Art | Jay F. McCuin | Set Dresser |
| Art | Brad Blei | Set Dresser |
| Art | Gen Quintanilla | Set Dresser |
| Art | Jeremy Reeves | Set Dresser |
| Art | Steve Sawhill | Set Dresser |
| Art | Steve Joyner | Property Master |
| Art | Caylah Eddleblute | Assistant Property Master |
| Art | Virginia Capobianco | Props |
| Art | Joe McCusker | Construction Coordinator |
| Art | Rodney Brown | Construction Foreman |
| Art | Ron Perkins | Construction Foreman |
| Art | Alan R. Serotta | Construction Foreman |
| Production | Kelly Kernan | Location Manager |
| Production | Joey Hudgins | Assistant Location Manager |
| Crew | Cecil D. Evans | Transportation Coordinator |
| Crew | Ronald D. Chambers | Transportation Captain |
| Crew | Dallas Smalley | Transportation Co-Captain |
| Sound | Dean Beville | Sound Designer |
| Sound | Dean Beville | Sound Supervisor |
| Sound | John Pospisil | Sound Effects |
| Sound | Stephen Hunter Flick | Sound Effects |
| Sound | William Jacobs | Sound Editor |
| Sound | Paula Fairfield | Sound Editor |
| Sound | Carla Murray | Sound Editor |
| Sound | Steven Ticknor | Sound Editor |
| Sound | David E. Stone | Sound Editor |
| Sound | Mike Chock | Sound Editor |
| Sound | Matthew C. Beville | Sound Editor |
| Sound | John Dunn | Foley Editor |
| Sound | John Dunn | Foley Supervisor |
| Sound | Charles Ewing Smith | Dialogue Editor |
| Sound | Nicholas James | Dialogue Editor |
| Sound | Dean Beville | ADR Editor |
| Sound | Dean Beville | ADR Supervisor |
| Sound | Tim Rakoczy | Assistant Sound Editor |
| Sound | Suren Wijeyaratne | Assistant Sound Editor |
| Sound | Carey Milbradt | Foley Artist |
| Sound | Sergio Reyes | Sound Re-Recording Mixer |
| Sound | Doug Andham | Sound Re-Recording Mixer |
| Sound | Tim Rakoczy | Music Editor |
| Sound | George Oldziey | Conductor |
| Sound | George Oldziey | Orchestrator |
| Crew | Adria Later | Studio Teacher |
| Crew | Elise Ganz | Studio Teacher |
| Production | Shalimar Reodica | Casting Associate |
| Production | Beth Sepko | Extras Casting |
| Production | Sheila Steele | Extras Casting Assistant |
| Editing | Jim Passon | Color Timer |
