Privédetective Sherlock Holmes en zijn vriend, huisgenoot en loyale assistent Dr. John Watson grijpen in bij een geheim ritueel waarbij ze de invloedrijke Lord Blackwood te pakken weten te krijgen. Blackwood verdwijnt achter de tralies en wordt veroordeeld tot de strop. Hij schijnt over duistere krachten te beschikken, kan dingen doen waar geen verklaring voor bestaat en beweert zelfs dat hij kan herrijzen uit de dood. Dit zorgt ervoor dat Holmes en Watson, bijgestaan door Irene Adler, zich onvrijwillig met hun 'laatste' zaak bezig moeten gaan houden.
Nee, helaas is Sherlock Holmes nog niet beschikbaar op Netflix in Nederland.
| Production | Steve Clark-Hall | Producer |
| Directing | Guy Ritchie | Director |
| Production | Dana Goldberg | Executive Producer |
| Production | Bruce Berman | Executive Producer |
| Writing | Michael Robert Johnson | Screenplay |
| Writing | Anthony Peckham | Screenplay |
| Production | Lionel Wigram | Producer |
| Writing | Simon Kinberg | Screenplay |
| Production | Susan Downey | Producer |
| Art | Sarah Greenwood | Production Design |
| Writing | Lionel Wigram | Screenstory |
| Writing | Michael Robert Johnson | Screenstory |
| Camera | Alex Bailey | Still Photographer |
| Writing | Arthur Conan Doyle | Characters |
| Production | Dan Lin | Producer |
| Production | Michael Tadross | Executive Producer |
| Editing | James Herbert | Editor |
| Production | Joel Silver | Producer |
| Camera | Philippe Rousselot | Director of Photography |
| Production | Peter Eskelsen | Producer |
| Costume & Make-Up | Jenny Beavan | Costume Design |
| Production | Reg Poerscout-Edgerton | Casting |
| Art | Katie Spencer | Set Decoration |
| Sound | Kevin Kaska | Orchestrator |
| Costume & Make-Up | Paul Mooney | Hairstylist |
| Art | Nick Gottschalk | Art Direction |
| Art | Matthew Gray | Art Direction |
| Costume & Make-Up | Lesa Warrener | Hairstylist |
| Costume & Make-Up | Lesa Warrener | Makeup Artist |
| Costume & Make-Up | Charmaine Fuller | Hairstylist |
| Costume & Make-Up | Julia Wilson | Hairstylist |
| Costume & Make-Up | Patricia Regan | Makeup Artist |
| Art | Niall Moroney | Supervising Art Director |
| Costume & Make-Up | Julia Wilson | Makeup Artist |
| Costume & Make-Up | Christine Blundell | Makeup Designer |
| Costume & Make-Up | Carol 'Ci Ci' Campbell | Hairstylist |
| Costume & Make-Up | Christine Blundell | Hair Designer |
| Costume & Make-Up | Chloe Meddings | Hairstylist |
| Art | James Foster | Art Direction |
| Camera | Des Whelan | Camera Operator |
| Camera | George Patsos | Key Grip |
| Costume & Make-Up | Peter White | Set Costumer |
| Crew | Rick Leary | CG Supervisor |
| Visual Effects | Chas Jarrett | Visual Effects Supervisor |
| Visual Effects | David Vickery | Visual Effects Supervisor |
| Camera | Alan Stewart | Second Unit Director of Photography |
| Camera | Vince McGahon | Steadicam Operator |
| Camera | Bobby Mancuso | First Assistant Camera |
| Lighting | Tommy Finch | Rigging Gaffer |
| Camera | Neal Norton | Steadicam Operator |
| Visual Effects | Mark Holt | Special Effects Supervisor |
| Sound | Luke Neuman | Boom Operator |
| Crew | Nick Jeffries | Armorer |
| Crew | Jeff Brink | Special Effects Coordinator |
| Lighting | Collin Quinlan | Chief Lighting Technician |
| Lighting | David Sinfield | Gaffer |
| Crew | Laurent Hugueniot | CG Supervisor |
| Visual Effects | Chloe Harrison | Visual Effects Coordinator |
| Sound | Dominic Gibbs | Sound Effects Editor |
| Sound | Andy Kennedy | Sound Effects Editor |
| Lighting | Jack English | Chief Lighting Technician |
| Visual Effects | Alexandra Daunt Watney | Visual Effects Producer |
| Camera | Julian Bucknall | First Assistant Camera |
| Costume & Make-Up | Charlotte Law | Assistant Costume Designer |
| Crew | Laura Jennings | Visual Effects Editor |
| Visual Effects | Tim Keene | Visual Effects Producer |
| Sound | James Mather | Supervising Sound Editor |
| Camera | John Flemming | Key Grip |
| Visual Effects | Sarah Tulloch | Visual Effects Coordinator |
| Visual Effects | Jonathan Fawkner | Visual Effects Supervisor |
| Editing | Todd Kleparski | Digital Intermediate |
| Costume & Make-Up | Melissa Meister | Assistant Costume Designer |
| Visual Effects | Dadi Einarsson | Animation Supervisor |
| Sound | Paul Munro | Boom Operator |
| Sound | Derek Trigg | Foley Editor |
| Lighting | Chuck Finch | Gaffer |
| Lighting | Greg Quinlan | Rigging Gaffer |
| Directing | Polly Hope | Script Supervisor |
| Visual Effects | Daniel Barrow | Visual Effects Producer |
| Sound | Doug Hemphill | Sound Re-Recording Mixer |
| Costume & Make-Up | Martin Mandeville | Costume Coordinator |
| Visual Effects | Day Yargici | 2D Artist |
| Sound | Becki Ponting | Dialogue Editor |
| Visual Effects | Claudia Dehmel | Visual Effects Producer |
| Sound | Michael Fentum | Sound Designer |
| Production | Emma Callinan | Casting Assistant |
| Sound | Andrew Schmetterling | Boom Operator |
| Editing | Matthew Bristowe | Digital Intermediate |
| Camera | Nick Ray | Key Grip |
| Lighting | Gus Magalios | Rigging Grip |
| Directing | Elizabeth West | Script Supervisor |
| Visual Effects | Pawl Fulker | Pre-Visualization Supervisor |
| Sound | Ron Bartlett | Sound Re-Recording Mixer |
| Costume & Make-Up | Clare Spragge | Costume Supervisor |
| Costume & Make-Up | Valentina Aulisi | Set Costumer |
| Camera | Louis Sabat | Dolly Grip |
| Camera | Olly Tellett | First Assistant Camera |
| Costume & Make-Up | Arlynn Abseck | Wardrobe Supervisor |
| Sound | Steve Little | Dialogue Editor |
| Sound | Peter Oso Snell | Music Editor |
| Art | Matthew Robinson | Assistant Art Director |
| Art | Gabi Brown | Art Department Coordinator |
| Art | Bradley Schmidt | Assistant Art Director |
| Art | Toni Barton | Assistant Art Director |
| Art | Helen Xenopoulos | Assistant Art Director |
| Art | John McDonnell | Assistant Property Master |
| Art | Michael Auszura | Assistant Art Director |
| Art | Robert Griffon Jr. | Property Master |
| Editing | Philip Hedgecock | First Assistant Editor |
| Art | Dennis Wiseman | Property Master |
| Art | Joseph K. Kepple IV | Art Department Coordinator |
| Sound | Steve Finn | Boom Operator |
| Crew | Richard Ryan | Stunts |
| Crew | Richard Dwyer | Stunts |
| Art | Elliot Scott | Runner Art Department |
| Art | Joseph S. Alfieri | Construction Coordinator |
| Crew | Michael Bloomberg | Thanks |
| Crew | Helen Steinway Bailey | Stunts |
| Crew | Jodi Michelle Pynn | Stunts |
| Crew | Heather Phillips | Stunts |
| Crew | Stephanie Lelievre | Stunts |
| Crew | Nina Armstrong | Stunts |
| Costume & Make-Up | Nadia Stacey | Other |
| Sound | Hans Zimmer | Original Music Composer |
| Sound | Ed Colyer | Foley Mixer |
| Sound | Peter Burgis | Foley Artist |
| Sound | Glen Gathard | Foley Mixer |
| Sound | Matt Gruber | Sound Re-Recording Mixer |
| Sound | Chris Munro | Sound Mixer |
| Sound | Nick Foley | ADR Mixer |
| Costume & Make-Up | Chris Lyons | Special Effects Makeup Artist |
| Costume & Make-Up | Nathaniel De'Lineadeus | Special Effects Makeup Artist |
| Costume & Make-Up | Matthew Smith | Prosthetic Makeup Artist |
| Costume & Make-Up | Nadia Stacey | Makeup Artist |
| Costume & Make-Up | Siân Miller | Makeup Artist |
| Crew | Sian Milne | Stunts |
