Bud en Doyle zijn net gedumpt door hun vriendinnen omdat ze volgens hen niet voldoende geven om het milieu. Wanneer Bud en Doyle per ongeluk opgesloten raken in een "Bio-Dome", om vervolgens een jaar zonder contact met de buitenwereld te leven, is dat dé kans om hun vriendinnen te bewijzen dat ze wel om het milieu geven.
Nee, helaas is Bio-Dome nog niet beschikbaar op Netflix in Nederland.
| Production | Bradley Jenkel | Producer |
| Production | Brad Krevoy | Producer |
| Production | Steven Stabler | Producer |
| Camera | Phedon Papamichael | Director of Photography |
| Editing | Christopher Greenbury | Editor |
| Directing | Jason Bloom | Director |
| Writing | Adam Leff | Story |
| Writing | Mitchell Peck | Story |
| Writing | Jason Blumenthal | Story |
| Writing | Kip Koenig | Writer |
| Writing | Scott Marcano | Writer |
| Directing | Rod Smith | First Assistant Director |
| Crew | Anita Hart | Stunts |
| Crew | Kurt Bryant | Stunt Coordinator |
| Crew | Joni Avery | Stunts |
| Sound | Andrew Gross | Original Music Composer |
| Crew | Denney Pierce | Utility Stunts |
| Crew | Nick Brett | Utility Stunts |
| Crew | Brett A. Jones | Stunts |
| Crew | Thomas DeWier | Utility Stunts |
| Crew | Hugh Aodh O'Brien | Stunts |
| Crew | James Ryan | Stunts |
| Crew | Michael J. Sarna | Stunts |
| Crew | Perry Barndt | Stunts |
| Production | Elaine Dysinger | Co-Producer |
| Production | Jason Blumenthal | Executive Producer |
| Production | Adam Leff | Executive Producer |
| Production | Dan Etheridge | Co-Producer |
| Production | Mitchell Peck | Executive Producer |
| Production | Michael Rotenberg | Executive Producer |
| Art | Amy Ancona | Set Decoration |
| Art | P. Michael Johnston | Production Design |
| Crew | Lou Carlucci | Special Effects |
| Camera | Patrick Loungway | Second Unit Director of Photography |
| Camera | Christopher Faloona | Additional Photography |
| Production | Dan Parada | Casting |
| Costume & Make-Up | Dugg Kirkpatrick | Key Hair Stylist |
| Costume & Make-Up | Mary Claire Hannan | Costume Design |
