De politiemannen Martin Riggs en Roger Murtaugh zijn terug. Deze keer komen ze in aanraking met een Afrikaanse diplomaat die gebruik maakt van zijn diplomatieke onschendbaarheid om zijn criminele activiteiten ongestraft te kunnen uitvoeren.
Nee, helaas is Lethal Weapon 2 nog niet beschikbaar op Netflix in Nederland.
| Art | Marvin March | Set Decoration |
| Sound | David Sanborn | Original Music Composer |
| Camera | Stephen Goldblatt | Director of Photography |
| Editing | Stuart Baird | Editor |
| Production | Gail Levin | Casting |
| Art | Richard Berger | Art Direction |
| Sound | Michael Kamen | Original Music Composer |
| Writing | Jeffrey Boam | Screenplay |
| Art | J. Michael Riva | Production Design |
| Production | Richard Donner | Producer |
| Directing | Richard Donner | Director |
| Sound | Eric Clapton | Original Music Composer |
| Production | Joel Silver | Producer |
| Production | Marion Dougherty | Casting |
| Directing | Nancy Hansen | Script Supervisor |
| Directing | Michael Alan Kahn | Second Assistant Director |
| Production | Peter Frankfurt | Associate Producer |
| Production | Jennie Lew Tugend | Co-Producer |
| Writing | Shane Black | Story |
| Production | Steve Perry | Co-Producer |
| Writing | Warren Murphy | Story |
| Costume & Make-Up | Barry Francis Delaney | Costume Supervisor |
| Camera | John R. Shannon | Still Photographer |
| Crew | Amy Jackson | Production Office Assistant |
| Crew | Jack Lietzke | Transportation Coordinator |
| Art | Virginia Randolph-Weaver | Art Direction |
| Sound | Bub Asman | Sound Editor |
| Art | Erik L. Nelson | Property Master |
| Crew | Charlie Picerni | Stunt Coordinator |
| Art | Sherman Labby | Production Illustrator |
| Art | Dianne Wager | Set Designer |
| Costume & Make-Up | Scott H. Eddo | Makeup Artist |
| Camera | Geary McLeod | First Assistant Camera |
| Crew | Michael Klastorin | Unit Publicist |
| Crew | Richmond G. Cogswell | Video Assist Operator |
| Directing | Terry Miller | First Assistant Director |
| Sound | Christopher Brooks | Music Editor |
| Camera | Frank M. Holgate | Aerial Camera |
| Crew | Julie Adams | Dialect Coach |
| Crew | Matt Sweeney | Special Effects Coordinator |
| Costume & Make-Up | Paul Abascal | Hairstylist |
| Crew | Frank DeMichelis | Craft Service |
| Sound | Willie D. Burton | Production Sound Mixer |
| Crew | Dan Pemberton | Propmaker |
| Production | Steve Perry | Unit Production Manager |
| Production | Gregory Manson | Production Accountant |
| Sound | Darrin Martin | Assistant Sound Editor |
| Sound | Robert G. Henderson | Supervising Sound Editor |
| Art | John Villarino | Construction Coordinator |
| Sound | Marvin E. Lewis | Boom Operator |
| Sound | Michael Kamen | Orchestrator |
| Art | Mike Villarino | Construction Foreman |
| Camera | Charles Saldaña | Key Grip |
| Crew | Michael Denering | Scenic Artist |
| Production | David Israel | Location Manager |
| Crew | Jophery C. Brown | Stunts |
| Writing | Shane Black | Characters |
| Crew | Don Hathaway | Special Effects |
| Sound | Alan Robert Murray | Supervising Sound Editor |
| Sound | Virginia Cook-McGowan | Sound Editor |
| Sound | Rick Alexander | Sound Re-Recording Mixer |
| Crew | Jon G. Belyeu | Special Effects Manager |
| Sound | Les Fresholtz | Sound Re-Recording Mixer |
| Sound | Ellen Heuer | Foley Artist |
| Crew | Chris Burton | Special Effects |
| Sound | Marshall Winn | Sound Editor |
| Crew | Calvin Joe Acord | Special Effects |
| Crew | Doyle Smiley | Special Effects |
| Crew | Steve Picerni | Stunts |
| Production | Mark Canton | Executive In Charge Of Production |
| Art | Jack Eberhart | Leadman |
| Crew | Jaymes Hinkle | Scenic Artist |
| Sound | Hank Salerno | Supervising ADR Editor |
| Crew | Steve Luport | Special Effects |
| Crew | Eddy Donno | Stunts |
| Crew | Gary McLarty | Stunts |
| Crew | Robert W. Harris | Cableman |
| Crew | Tommy J. Huff | Stunts |
| Crew | Mic Rodgers | Stunts |
| Sound | Neil Burrow | Sound Editor |
| Sound | Walter Newman | Sound Editor |
| Crew | Richard L. Hill | Special Effects |
| Crew | Gilbert B. Combs | Stunts |
| Crew | James M. Halty | Stunts |
| Crew | Norman Howell | Stunts |
| Crew | Marc Fambro | Carpenter |
| Sound | Teri E. Dorman | Sound Editor |
| Sound | Joseph A. Ippolito | Sound Editor |
| Sound | Vern Poore | Sound Re-Recording Mixer |
| Crew | David Peterson | Special Effects |
| Crew | Paul Sabourin | Special Effects |
| Crew | Janet Brady | Stunts |
| Crew | Chuck Picerni Jr. | Stunts |
| Sound | David M. Horton | Sound Editor |
| Crew | Gary Davis | Stunts |
| Crew | Victor Paul | Stunts |
| Crew | Charlie Picerni | Stunts |
| Directing | Charlie Picerni | Second Unit Director |
| Crew | Bob Stoker | Special Effects |
| Crew | Kenny Endoso | Stunts |
| Crew | Billy Hank Hooker | Stunts |
| Crew | Fred Tessaro | Special Effects |
| Crew | Steve Boyum | Stunts |
| Crew | Matt Johnston | Stunts |
| Crew | Bennie Moore | Stunts |
| Crew | Frank Orsatti | Stunts |
| Crew | Chad Randall | Stunts |
| Crew | Lucinda Strub | Special Effects |
| Crew | Sparky Edmonston | Stunts |
| Costume & Make-Up | Barbara Siebert | Costumer |
| Costume & Make-Up | Michael Voght | Costumer |
| Lighting | Damon Marcellino | Lighting Technician |
| Production | Antoinette Simmrin | Location Manager |
| Sound | Bruce Babcock | Orchestrator |
| Sound | Michael Kamen | Musician |
| Sound | Malcolm McNab | Musician |
| Directing | Julie Pitkanen | Script Supervisor |
| Crew | John M. Woodward | Transportation Captain |
| Camera | Frank M. Holgate | Underwater Camera |
| Sound | Philip Giffin | Orchestrator |
| Sound | Tom Boyd | Musician |
| Lighting | Malcolm Bryce | Lighting Technician |
| Camera | Stephen St. John | Camera Operator |
| Sound | Vince De Rosa | Musician |
| Editing | David Mann | Assistant Editor |
| Editing | Kevin Stitt | Assistant Editor |
| Crew | Danny Rogers | Stunts |
| Crew | Keith Tellez | Stunts |
| Crew | Ric Roman Waugh | Stunts |
| Camera | Horace Jordan | First Assistant Camera |
| Production | Alicia Rivera Frankl | Production Accountant |
| Crew | Eddie L. Watkins | Stunts |
| Lighting | Bill Krattiger | Lighting Technician |
| Production | Lisa Cogswell | Production Coordinator |
| Camera | Robert D. McBride | Camera Operator |
| Editing | William J. Meshover | Assistant Editor |
| Camera | Bess Wiley | Second Assistant Camera |
| Sound | Alan Kaplan | Musician |
| Sound | Richard Nash | Musician |
| Crew | Tommie Turvey | Stunts |
| Camera | Ray De La Motte | Camera Operator |
| Lighting | Adam Glick | Lighting Technician |
| Sound | James Thatcher | Musician |
| Sound | Chris Boardman | Orchestrator |
| Sound | Louise Di Tullio | Musician |
| Art | Paul J. Campanella | Standby Painter |
| Crew | Gary Epper | Stunts |
| Crew | Tony Epper | Stunts |
| Crew | Buddy Joe Hooker | Stunts |
| Sound | Bill Voigtlander | ADR Editor |
| Crew | Larry L. Fuentes | Special Effects |
| Crew | Freddie Hice | Stunts |
| Crew | Mic Rodgers | Stunt Coordinator |
| Art | David J. Negrón Jr. | Storyboard Artist |
| Sound | Michael Jiron | Sound Re-Recording Mixer |
| Sound | Karen Minahan | Assistant Sound Editor |
| Sound | Brooke Henderson Ward | Assistant Sound Editor |
| Sound | Joseph T. Sabella | Foley Artist |
| Crew | Scott Wilder | Stunts |
| Camera | John Earl Burnett | First Assistant Camera |
| Production | Joel Marx | Location Manager |
| Sound | Michael Kamen | Conductor |
| Sound | Norman Ludwin | Musician |
| Camera | Stephen Ashley Blake | Second Unit Director of Photography |
| Crew | Jim Schwalm | Special Effects |
| Crew | Greg C. Jensen | Special Effects |
| Crew | David Burton | Stunts |
| Crew | Steven Chambers | Stunts |
| Crew | John C. Meier | Stunts |
| Crew | R.A. Rondell | Stunts |
| Crew | Lane Leavitt | Stunts |
| Sound | Tommy Johnson | Musician |
| Crew | Michael Papac | Weapons Master |
| Camera | Hal Nelson | Best Boy Grip |
| Writing | Robert Mark Kamen | Script Editor |
| Crew | Gregory J. Barnett | Stunts |
| Sound | Stephen McLaughlin | Music Producer |
| Directing | Albert Cho | Second Second Assistant Director |
| Art | Gary F. Kieldrup | Assistant Property Master |
| Sound | John Roesch | Foley Artist |
| Sound | Carolyn Tapp | Foley Recordist |
| Sound | Jay Engel | Supervising ADR Editor |
| Camera | Kirk Bales | Second Assistant Camera |
| Costume & Make-Up | Vicky Snow | Costumer |
| Sound | James Simcik | ADR Editor |
| Production | Lisa Cogswell | Production Secretary |
| Sound | Greg Orloff | Foley Mixer |
| Production | Kristin Dewey | Assistant Location Manager |
| Crew | Charles A. Tamburro | Aerial Coordinator |
| Crew | Craig Lietzke | Stunt Driver |
| Directing | Steve Perry | Second Unit Director |
| Crew | Mic Rodgers | Stunt Double |
| Crew | Gilbert O. Parra | Technical Advisor |
| Lighting | Bob E. Krattiger | Assistant Chief Lighting Technician |
| Camera | Danny Falkengren | Dolly Grip |
| Lighting | Gary Holt | Chief Lighting Technician |
| Crew | Dick Ziker | Stunts |
