De inwoners van een mijnwerkersdorp ontdekken dat een chemisch ongelukje er voor gezorgd heeft dat honderden kleine spinnen gemuteerd zijn tot hongerige monsters van meters groot. Het is aan mijnwerker Chris McCormack en sheriff Sam Parker om een groep mensen bij elkaar te zoeken om de de bloeddorstige beesten te bestrijden. Onder hen zijn de kinderen van de sheriff (Mike en Ashley) en de paranoïde radiomaker Harlan.
Nee, helaas is Eight Legged Freaks nog niet beschikbaar op Netflix in Nederland.
| Directing | Ellory Elkayem | Director |
| Writing | Jesse Alexander | Screenplay |
| Production | William Fay | Executive Producer |
| Production | Bruce Berman | Producer |
| Production | Roland Emmerich | Executive Producer |
| Production | Peter Winther | Executive Producer |
| Sound | John Ottman | Original Music Composer |
| Production | Dean Devlin | Producer |
| Camera | John S. Bartley | Director of Photography |
| Writing | Ellory Elkayem | Screenplay |
| Production | April Webster | Casting |
| Production | Paula Rosenberg | Casting |
| Crew | Louie Franco | Stunt Driver |
| Crew | 'Mad' Mike Jones | Stunt Driver |
| Art | Matthew Bekoff | Set Designer |
| Crew | Jim Holley | Stunt Driver |
| Crew | Pat Banta | Stunts |
| Crew | Rick Miller | Stunt Driver |
| Crew | John Hateley | Stunts |
| Crew | James M. Churchman | Stunts |
| Crew | Heather Callow | Stunts |
| Editing | David Siegel | Editor |
| Costume & Make-Up | Alix Friedberg | Costume Design |
| Sound | Gary Mundheim | Sound Effects Editor |
| Visual Effects | Thomas Dadras | Visual Effects Supervisor |
| Sound | Dino DiMuro | Sound Effects Editor |
| Editing | Michel Aller | First Assistant Editor |
| Art | Marcia Calosio | Set Decoration |
| Art | Richard Lambert | Leadman |
| Costume & Make-Up | Kim Collea | Makeup Artist |
| Sound | James Moriana | Foley |
| Camera | Curt Pair | Camera Operator |
| Art | Terry Kempf | Construction Coordinator |
| Sound | Jim Fitzpatrick | Sound Re-Recording Mixer |
| Art | Beverli Eagan | Set Designer |
| Visual Effects | Drew McKeen | Visual Effects Producer |
| Visual Effects | Joachim Grüninger | Visual Effects Supervisor |
| Costume & Make-Up | Deborah Hall | Costume Supervisor |
| Camera | Gary L. Camp | Steadicam Operator |
| Camera | Jon Baronn Farmer | Still Photographer |
| Visual Effects | Karen E. Goulekas | Visual Effects Supervisor |
| Art | Catherine A. McCabe | Art Department Coordinator |
| Sound | Christopher Assells | Sound Effects Editor |
| Sound | Kerry Ann Carmean | Sound Effects Editor |
| Sound | Scott Wolf | Supervising Sound Editor |
| Sound | Amanda Goodpaster | Music Editor |
| Crew | Yves De Bono | Special Effects Coordinator |
| Art | Chas. Butcher | Art Direction |
| Sound | Dan Hegeman | Sound Effects Editor |
| Crew | Charlie Brewer | Stunt Coordinator |
| Costume & Make-Up | Gina G. Aller | Set Costumer |
| Crew | Terry J. Erdmann | Unit Publicist |
| Crew | Kosta Saric | Visual Effects Editor |
| Visual Effects | Kelvin Lee | Animation Supervisor |
| Crew | Jo Ann Smith | Studio Teachers |
| Costume & Make-Up | Rick Sharp | Makeup Department Head |
| Sound | Gary Gegan | Sound Re-Recording Mixer |
| Camera | Anna Foerster | Additional Photography |
| Directing | Robin Anderson | Script Supervisor |
| Production | Alan Benoit | Location Manager |
| Production | Kelly Van Horn | Co-Producer |
| Crew | James Marbas | Digital Effects Supervisor |
| Crew | Gregg Singer | Picture Car Coordinator |
| Costume & Make-Up | Scott W. Farley | Key Hair Stylist |
| Crew | Rich Ragsdale | Additional Music |
| Crew | Michael B. Russell | Transportation Captain |
| Art | Kristen Spinning | Standby Painter |
| Crew | Steve Roll | Carpenter |
| Crew | John Alden | Stunts |
| Crew | George Bolton | Driver |
| Crew | Marie Randall | Craft Service |
| Crew | Leo Corey Castellano | Makeup Effects |
| Costume & Make-Up | Claudia Breckenridge | Hairstylist |
| Crew | John W. Ervin | Set Production Assistant |
| Camera | David E. Baron | First Assistant Camera |
| Crew | James K. Jensen | Post Production Supervisor |
| Crew | Mike McNally | Set Medic |
| Crew | Neil Gahm | Propmaker |
| Sound | Peter Afterman | Music Supervisor |
| Sound | Jeff Glueck | Sound Engineer |
| Writing | Randy Kornfield | Story |
| Visual Effects | Jens Döldissen | Special Effects Supervisor |
| Writing | Ellory Elkayem | Story |
| Production | Karen O'Toole | Production Coordinator |
| Sound | Kate Jesse | Boom Operator |
| Sound | Daniel S. Irwin | Sound Editor |
| Production | Daryl C. Lefever | Production Accountant |
| Visual Effects | Tim T. Cunningham | Visual Effects Coordinator |
| Sound | Peter Geoco | Production Sound Mixer |
| Production | Scott Baldyga | Casting Associate |
| Visual Effects | Andy Barrios | Digital Compositors |
| Sound | Casey Stone | Scoring Mixer |
| Sound | Larry Groupé | Orchestrator |
| Art | Charles William Breen | Production Design |
| Production | Kelly Van Horn | Unit Production Manager |
| Crew | Alex Madison | Stunts |
| Art | Vicki Dittemore | Set Dresser |
| Directing | Paul Bernard | Second Assistant Director |
| Editing | Mo Henry | Negative Cutter |
| Crew | Lewis Arquette | In Memory Of |
| Sound | Damon Intrabartolo | Conductor |
| Art | John A. Stewart Jr. | Assistant Property Master |
| Camera | Tim Ryan | Key Grip |
| Crew | Cris Rankin | Animal Wrangler |
| Lighting | John Stewart | Underwater Gaffer |
| Sound | George Doering | Musician |
| Costume & Make-Up | Maggie McFarland | Key Set Costumer |
| Production | Cindy Franke | Assistant Production Coordinator |
| Visual Effects | Carol Ashley | 3D Artist |
| Directing | Lars P. Winther | First Assistant Director |
| Visual Effects | Andrew Tamandl | VFX Artist |
| Editing | David Orr | Color Timer |
| Art | Keith Mosca | Property Master |
| Crew | Andy Gill | Stunts |
| Camera | Gary L. Camp | "B" Camera Operator |
| Camera | Michael Green | "A" Camera Operator |
| Visual Effects | Xye | Visual Effects |
| Costume & Make-Up | Tina Sims | Assistant Hairstylist |
| Camera | Roy Heath | Grip |
| Sound | Dirk Stout | Utility Sound |
| Camera | Jay Coolidge | First Assistant "B" Camera |
| Lighting | Scott Herrick | Rigging Gaffer |
| Visual Effects | Abra Grupp | Compositing Supervisor |
| Lighting | Kenny Christiansen | Best Boy Electric |
| Production | Karen Turner | Payroll Accountant |
| Crew | Ron Colucci | Special Effects |
| Crew | Ron Colucci | Special Effects Technician |
| Crew | Kim Hyde | Set Medic |
| Sound | Ron Bedrosian | ADR Mixer |
| Crew | Ken Gorrell | Special Effects Technician |
| Editing | Ryan Chan | Assistant Editor |
| Production | Shari Lee | Production Secretary |
| Sound | Brian Basham | ADR Recordist |
| Visual Effects | John Bozzalla | Visual Effects Production Assistant |
| Production | Cindi Reiss | Extras Casting |
| Production | Shelly Boucher | Production Assistant |
| Sound | Michael J. Broomberg | Foley Artist |
| Visual Effects | Greg Groenekamp | Visual Effects Compositor |
| Costume & Make-Up | Blanca Garcia | Costumer |
| Production | Christian Feldhaus | First Assistant Accountant |
| Art | Mark Hurtado | Storyboard Artist |
| Camera | Jason Casillas | Assistant Camera |
| Camera | Matt Balzarini | Second Assistant Camera |
| Sound | Jessica Clements | Music Coordinator |
| Sound | Damon Intrabartolo | Orchestrator |
| Crew | Freddy Mojica | Catering |
