Mexico, 1916. Het arme dorpje Santa Poco wordt geteisterd door de moorddadige bende van El Guapo. De mooie dorpsbewoonster Carmen hoopt op de hulp van de '3 Amigos' om hen te bevrijden van deze bandieten. Ze kent deze mannen van het witte doek en stuurt hen een telegram. De 3 Amigos zijn de drie Hollywoodacteurs Lucky, Dusty en Ned, die in hun films het kwaad bestrijden en natuurlijk ook overwinnen. Ze werden zopas door filmmagnaat Flugelman ontslagen en zijn dan ook blij met het telegram dat zij interpreteren als een uitnodiging om in Santa Poco op te treden.
Nee, helaas is ¡Three Amigos! nog niet beschikbaar op Netflix in Nederland.
| Directing | John Landis | Director |
| Writing | Lorne Michaels | Screenplay |
| Production | Lorne Michaels | Producer |
| Writing | Randy Newman | Screenplay |
| Writing | Steve Martin | Screenplay |
| Sound | Elmer Bernstein | Original Music Composer |
| Camera | Ronald W. Browne | Director of Photography |
| Production | Steve Martin | Executive Producer |
| Production | George Folsey Jr. | Producer |
| Production | Leslie Belzberg | Associate Producer |
| Editing | Malcolm Campbell | Editor |
| Art | Richard Sawyer | Production Design |
| Production | Jackie Burch | Casting Director |
| Art | John Marshall | Art Direction |
| Art | Gregory Pickrell | Art Direction |
| Art | Richard C. Goddard | Set Decoration |
| Costume & Make-Up | Deborah Nadoolman Landis | Costume Designer |
| Costume & Make-Up | Frank Griffin | Makeup Artist |
| Costume & Make-Up | Leonard Engelman | Makeup Artist |
| Costume & Make-Up | Mark Reedall | Makeup Artist |
| Costume & Make-Up | Ric Sagliani | Makeup Artist |
| Costume & Make-Up | Virginia Darcy | Hairstylist |
| Costume & Make-Up | Jean Austin | Hairstylist |
| Costume & Make-Up | Virginia G. Hadfield | Hairstylist |
| Costume & Make-Up | Linda Trainoff | Hairstylist |
| Visual Effects | Norm Stangl | Visual Effects |
| Visual Effects | Norm Stangl | Animation |
| Visual Effects | Cynthia Ward | Animation |
| Art | Lisa Atkinson | Painter |
| Sound | Jeff Bushelman | Sound Editor |
| Sound | Gary Alexander | Sound Re-Recording Mixer |
| Sound | Charles L. Campbell | Sound Editor |
| Sound | Larry Carow | Sound Editor |
| Sound | Samuel C. Crutcher | Sound Editor |
| Sound | Don Digirolamo | Sound Re-Recording Mixer |
| Sound | Louis L. Edemann | Sound Editor |
| Sound | Richard C. Franklin | Sound Editor |
| Sound | Robert Glass | Sound Recordist |
| Sound | Gary A. Hecker | Foley Artist |
| Sound | William B. Kaplan | Sound Mixer |
| Sound | Robert 'Buzz' Knudson | Sound Recordist |
| Sound | Colin C. Mouat | Sound Editor |
| Sound | Chuck Neely | Sound Editor |
| Sound | Greg Orloff | Foley Mixer |
| Sound | Jerry Stanford | Sound Editor |
| Sound | Larry Stensvold | Sound Recordist |
| Sound | David A. Whittaker | Sound Editor |
| Sound | John Roesch | Foley Artist |
| Crew | Gene Hartline | Stunts |
| Crew | Danny Costa | Stunts |
| Crew | Phil Culotta | Stunts |
| Crew | Tom Elliott | Stunts |
| Crew | Steve Cremin | Stunts |
| Crew | Richard Epper | Stunts |
| Crew | Joe Finnegan | Stunts |
| Crew | Gil Escandon | Stunts |
| Crew | Marguerite Happy | Stunts |
| Crew | Jerry Gatlin | Stunt Coordinator |
| Crew | Clifford Happy | Stunts |
| Crew | Daniel Holguín | Stunts |
| Crew | Johnny Hock | Stunt Double |
| Crew | Tracy Keehn-Dashnaw | Stunts |
| Crew | Walt La Rue | Stunts |
| Crew | Robert Jauregui | Stunt Double |
| Crew | Clay M. Lilley | Stunts |
| Crew | Jack Lilley | Stunts |
| Crew | Daniel O'Haco | Stunts |
| Crew | Kathleen O'Haco | Stunt Double |
| Crew | Mike H. McGaughy | Stunts |
| Crew | Cole S. McKay | Stunts |
| Crew | Bobby McLaughlin | Stunts |
| Crew | Larry Randles | Stunts |
| Crew | Ben Scott | Stunts |
| Crew | Michael Stull | Stunts |
| Crew | Thomas Rosales Jr. | Stunts |
| Crew | R.L. Tolbert | Stunts |
| Crew | Robert Tebow | Stunts |
| Crew | Mike Watson | Stunts |
| Crew | Rock A. Walker | Stunt Double |
| Lighting | Norman Glasser | Gaffer |
| Camera | Philip Caplan | Camera Operator |
| Crew | Roy Arbogast | Special Effects |
| Directing | David Sosna | First Assistant Director |
| Directing | George Folsey Jr. | Second Unit Director |
| Directing | John M. Stephens | Second Unit Director |
| Directing | Victoria E. Rhodes | Second Assistant Director |
| Directing | Rob Corn | Second Assistant Director |
| Art | Dan Curry | Title Designer |
| Art | Sharon Haskell | Title Designer |
| Crew | Loren Janes | Stunts |
| Crew | Jennifer Watson-Johnston | Stunts |
| Crew | Bruce Randall | Stunts |
| Crew | Debbie Evans | Stunts |
| Crew | Bob Herron | Stunts |
