Bob is de leider van een groep junkies die het land rondreizen en apotheken beroven om zo aan hun drugs te komen. Wanneer één van de jonge verslaafden overlijdt aan een overdosis, moet Bob bepalen hoe ze verder moeten gaan.
Nee, helaas is Drugstore Cowboy nog niet beschikbaar op Netflix in Nederland.
| Writing | Gus Van Sant | Screenplay |
| Writing | Daniel Yost | Screenplay |
| Production | Richard Pagano | Casting |
| Art | Margaret Goldsmith | Set Decoration |
| Camera | Robert D. Yeoman | Director of Photography |
| Production | Sharon Bialy | Casting |
| Directing | Gus Van Sant | Director |
| Art | Eve Cauley | Art Direction |
| Art | David Brisbin | Production Design |
| Sound | Elliot Goldenthal | Original Music Composer |
| Production | Karen Murphy | Producer |
| Production | Nick Wechsler | Producer |
| Production | Cary Brokaw | Executive Producer |
| Editing | Mary Bauer | Editor |
| Directing | Jane Goldsmith | Script Supervisor |
| Costume & Make-Up | Gina Monaci | Hair Designer |
| Costume & Make-Up | Lizbeth Williamson | Makeup Artist |
| Sound | Joel Iwataki | Sound Engineer |
| Editing | Curtiss Clayton | Editor |
| Production | Laurie Parker | Production Executive |
| Production | Claudia Lewis | Production Executive |
| Sound | Jerry Trent | Foley Artist |
| Directing | Robin Leigh Fleck | Second Assistant Director |
| Camera | Les Percy | Key Grip |
| Crew | Leslie A. Leitner | Post Production Supervisor |
| Sound | Joan Rowe | Foley Artist |
| Sound | Matthew Iadarola | Sound Re-Recording Mixer |
| Production | Charles Harrington | Location Manager |
| Writing | James Fogle | Novel |
| Sound | Robert Jackson | Boom Operator |
| Sound | Dane A. Davis | Supervising Sound Editor |
| Sound | Wayne Heitman | Sound Re-Recording Mixer |
| Production | Karen Koch | Production Manager |
| Art | Missy Stewart | Set Dresser |
| Sound | Mark 'Frito' Long | Sound Recordist |
| Costume & Make-Up | Beatrix Aruna Pasztor | Costume Designer |
| Sound | John Kwiatkowski | Sound Effects Editor |
| Production | Eric McLeod | Production Coordinator |
| Crew | David Boushey | Stunt Coordinator |
| Directing | David B. Householter | First Assistant Director |
| Art | Michael Gastaldo | Property Master |
| Camera | Eric Alan Edwards | Second Unit Director of Photography |
| Sound | Ron Judkins | Sound Mixer |
| Costume & Make-Up | Marsha Perloff | Wardrobe Supervisor |
| Lighting | Chris Morley | Gaffer |
