Bleek is er als kind al vroeg bij met trompetles. Hij groeit op in de volwassen wereld en vormt zijn eigen band, The Bleek Gilliam Quartet. Maar hun professionele band dreigt uit elkaar te vallen door Bleek's en Shadow's tegenstanders.
Nee, helaas is Mo' Better Blues nog niet beschikbaar op Netflix in Nederland.
| Writing | Spike Lee | Writer |
| Directing | Spike Lee | Director |
| Camera | Ernest R. Dickerson | Director of Photography |
| Sound | Bill Lee | Original Music Composer |
| Production | Spike Lee | Producer |
| Editing | Sam Pollard | Editor |
| Sound | Skip Lievsay | Sound Designer |
| Directing | Randy Fletcher | First Assistant Director |
| Directing | Dale Pierce-Johnson | Second Assistant Director |
| Directing | Dale M. Nielsen | Second Second Assistant Director |
| Directing | H.H. Cooper | Second Assistant Director |
| Art | Ted Glass | Set Decoration |
| Art | Wynn Thomas | Production Design |
| Costume & Make-Up | Ruth E. Carter | Costume Design |
| Production | Jon Kilik | Line Producer |
| Production | Monty Ross | Co-Producer |
| Production | Robi Reed | Casting Director |
| Costume & Make-Up | Marjorie Durand | Key Makeup Artist |
| Sound | Terence Blanchard | Musician |
| Art | Randall Balsmeyer | Title Designer |