Bleek is er als kind al vroeg bij met trompetles. Hij groeit op in de volwassen wereld en vormt zijn eigen band, The Bleek Gilliam Quartet. Maar hun professionele band dreigt uit elkaar te vallen door Bleek's en Shadow's tegenstanders.
Nee, helaas is Mo' Better Blues nog niet beschikbaar op Netflix in Nederland.
| Directing | Spike Lee | Director |
| Writing | Spike Lee | Writer |
| Camera | Ernest R. Dickerson | Director of Photography |
| Sound | Bill Lee | Original Music Composer |
| Production | Spike Lee | Producer |
| Editing | Sam Pollard | Editor |
| Sound | Skip Lievsay | Sound Designer |
| Directing | H.H. Cooper | Second Assistant Director |
| Directing | Randy Fletcher | First Assistant Director |
| Directing | Dale Pierce-Johnson | Second Assistant Director |
| Directing | Dale M. Nielsen | Second Second Assistant Director |
| Production | Jon Kilik | Line Producer |
| Costume & Make-Up | Marjorie Durand | Key Makeup Artist |
| Art | Ted Glass | Set Decoration |
| Costume & Make-Up | Ruth E. Carter | Costume Design |
| Production | Robi Reed | Casting Director |
| Art | Wynn Thomas | Production Design |
| Production | Monty Ross | Co-Producer |
| Sound | Terence Blanchard | Musician |