In de nabije toekomst heeft Amerika de strijd tegen drugs verloren en laten geheimagenten naast hun identiteit ook hun gezicht veranderen. Fred (Keanu Reeves) is zo’n undercoveragent, die een probleem krijgt wanneer hij teveel drugs (het populaire Substance D.) gebruikt, waardoor hij schizofreen wordt. Hierdoor ontstaat Fred's alter ego Bob, een meedogenloze drugsdealer.
Nee, helaas is A Scanner Darkly nog niet beschikbaar op Netflix in Nederland.
| Writing | Philip K. Dick | Novel |
| Art | Joaquin A. Morin | Set Decoration |
| Production | Steven Soderbergh | Executive Producer |
| Production | Jennifer Fox | Executive Producer |
| Production | Denise Chamian | Casting |
| Writing | Richard Linklater | Screenplay |
| Production | Erwin Stoff | Producer |
| Production | Ben Cosgrove | Executive Producer |
| Production | Anne Walker-McBay | Producer |
| Production | Palmer West | Producer |
| Sound | Graham Reynolds | Original Music Composer |
| Art | Bruce Curtis | Production Design |
| Production | George Clooney | Executive Producer |
| Production | John Sloss | Executive Producer |
| Production | Jonah Smith | Producer |
| Production | Tommy Pallotta | Producer |
| Editing | Sandra Adair | Editor |
| Directing | Richard Linklater | Director |
| Camera | Shane F. Kelly | Director of Photography |
| Costume & Make-Up | Darylin Nagy | Makeup Department Head |
| Costume & Make-Up | Kari Perkins | Costume Design |
| Costume & Make-Up | Melanie Armstrong Fletcher | Costume Supervisor |
| Art | Fred Daniel | Art Department Coordinator |
| Directing | Brooke Satrazemis | Script Supervisor |
| Sound | Tom Hammond | Sound Designer |
| Sound | Justin Hennard | Sound Effects Editor |
| Sound | Skip Lievsay | Sound Re-Recording Mixer |
| Sound | Jeremy Peirson | Sound Re-Recording Mixer |
| Visual Effects | Richard Gordoa | Visual Effects Supervisor |
| Visual Effects | Sterling Allen | Lead Animator |
| Visual Effects | Jason Archer | Head of Animation |
| Visual Effects | Evan Cagle | Lead Animator |
| Visual Effects | Nick Derington | Lead Animator |
| Production | Sara Johnson | Associate Producer |
| Production | Erin Ferguson | Co-Producer |
| Costume & Make-Up | Katina Gilkey | Hairstylist |
| Costume & Make-Up | Darylin Nagy | Hair Department Head |
| Production | Susan Kirr | Unit Production Manager |
| Directing | Vincent Palmo Jr. | First Assistant Director |
| Directing | Andrew Payer | Second Second Assistant Director |
| Directing | Kathie Tull | Second Assistant Director |
| Art | Brad Blei | Set Dresser |
| Art | Raymond Consing | Storyboard Artist |
| Costume & Make-Up | Melanie Ferguson | On Set Dresser |
| Art | Erick Garibay | Assistant Property Master |
| Art | Ian Sebastian Kasnoff | Construction Coordinator |
| Art | Stefan Wilcox | Property Master |
| Sound | Ethan Andrus | Production Sound Mixer |
| Sound | Gregg Barbanell | Foley Artist |
| Sound | Ajae Clearway | ADR Editor |
| Sound | Ajae Clearway | Dialogue Editor |
| Sound | Tom Hammond | Supervising Sound Editor |
| Sound | Thomas J. O'Connell | ADR Mixer |
| Sound | Jason Piatt | Foley Mixer |
| Sound | Tom Sturgis | Boom Operator |
| Sound | Michael Swanner | Utility Sound |
| Sound | Peter Germansen | Sound Engineer |
| Crew | Steve Krieger | Special Effects Coordinator |
| Crew | Tod Campbell | Loader |
| Camera | Matt Cowan | Best Boy Grip |
| Camera | Matt Lankes | Still Photographer |
| Camera | Mike Reyes | Grip |
| Lighting | Robert B. Reynolds | Chief Lighting Technician |
| Camera | Peter Simonite | First Assistant Camera |
| Lighting | Josh Taylor | Assistant Chief Lighting Technician |
| Camera | Aaron Atom Vyvial | Key Grip |
| Camera | Ralph Watson | Camera Operator |
| Production | Scout Masterson | Casting Associate |
| Production | Beth Sepko | Local Casting |
| Editing | Christopher Roldan | First Assistant Editor |
| Production | Peter Atherton | Location Manager |
| Production | Dustin Weaver | Assistant Location Manager |
| Sound | Bruce Colson | Musician |
| Sound | Nic Ratner | Music Supervisor |
| Crew | Ronald D. Chambers | Transportation Coordinator |
| Crew | Jesus F. Tellez | Transportation Captain |
| Production | Shannon Blackburn | Production Secretary |
| Production | Dominic Cancilla | Production Coordinator |
| Crew | Gil Dean | Animal Wrangler |
| Crew | Lisa Del Dotto | Assistant Craft Service |
| Art | Michael P. Garza | Title Designer |
| Crew | Melody Lloyd | Set Medic |
| Production | Morgan Miles | Production Accountant |
| Crew | Tracey Schaefer | Unit Publicist |
