De film speelt zich af op de jungle-achtige thuisplaneet van de Predators. Op deze planeet huist ook een 'Mega-Predator' die elk jaar een groep van de gevaarlijkste individuen van de planeet aarde ontvoert, om ze vervolgens als prooi vrij te laten in de dodelijke jungle van de Predator-thuisplaneet. Royce (Adrien Brody) is de leider van een groepje huurlingen, dat onder andere bestaat uit een taaie vrouwelijke moordenaar, een man die totaal niet bang is om te sterven en een voormalige Russisch geheimagent. Samen moeten ze zien te overleven in de wildernis terwijl ze wanhopig proberen uit te vinden wat er met hen is gebeurd en door wie of wat ze worden opgejaagd...
Nee, helaas is Predators nog niet beschikbaar op Netflix in Nederland.
| Directing | Nimród Antal | Director |
| Writing | Alex Litvak | Writer |
| Writing | Michael Finch | Writer |
| Production | Robert Rodriguez | Producer |
| Production | Elizabeth Avellan | Producer |
| Production | Alex Young | Executive Producer |
| Sound | John Debney | Original Music Composer |
| Camera | Gyula Pados | Director of Photography |
| Editing | Dan Zimmerman | Editor |
| Costume & Make-Up | Nina Proctor | Costume Design |
| Production | John Davis | Producer |
| Production | Jaina Ashton | Casting |
| Production | J.C. Cantu | Casting |
| Production | Mary Vernieu | Casting |
| Directing | Gina Grande | Script Supervisor |
| Writing | Jim Thomas | Characters |
| Art | Caylah Eddleblute | Production Design |
| Art | Steve Joyner | Production Design |
| Art | David Hack | Set Decoration |
| Costume & Make-Up | Ermahn Ospina | Makeup Department Head |
| Costume & Make-Up | Joe Rivera | Hair Department Head |
| Directing | Brian Bettwy | First Assistant Director |
| Art | Jeff B. Adams Jr. | Set Designer |
| Art | Pedro Barquin | Greensman |
| Art | Richard J. Bell | Greensman |
| Art | Mark Hanks | Leadman |
| Art | Ana Martínez | Art Department Coordinator |
| Art | Joe McCusker | Construction Coordinator |
| Art | Adele Plauche | Set Designer |
| Art | Tommy Tomlinson | Property Master |
| Sound | Joaquin Gonzalo Avellán | Foley Editor |
| Sound | David Bach | ADR Editor |
| Sound | Brad Engleking | Dialogue Editor |
| Sound | Paula Fairfield | Sound Designer |
| Sound | William Jacobs | Sound Editor |
| Sound | Carla Murray | Sound Designer |
| Sound | Angelo Palazzo | Sound Effects Editor |
| Sound | Tim Rakoczy | Supervising Sound Editor |
| Sound | Tom Sturgis | Boom Operator |
| Sound | Clayton Weber | Foley Editor |
| Crew | Joe Montenegro | Special Effects Coordinator |
| Visual Effects | Richard Wood | Special Effects Supervisor |
| Visual Effects | Jabbar Raisani | Visual Effects Supervisor |
| Crew | Travis Smith | Visual Effects Editor |
| Lighting | jonathan Swartz | Lighting Director |
| Lighting | Sean Noel Walker | Lighting Director |
| Crew | Jeffrey J. Dashnaw | Stunt Coordinator |
| Crew | Steve M. Davison | Stunt Coordinator |
| Lighting | Colin J. Campbell | Gaffer |
| Camera | Neil Fraser | Dolly Grip |
| Camera | Mark Gerasimenko | Camera Operator |
| Lighting | Spencer Pharr | Lighting Technician |
| Camera | Ferrell A. Shinnick | Key Grip |
| Camera | Henry Tirl | Steadicam Operator |
| Camera | Rico Torres | Still Photographer |
| Costume & Make-Up | Amy Maner | Costume Supervisor |
| Costume & Make-Up | Cindy Renaud-Kim | Tailor |
| Production | Logan Cooper | Location Manager |
| Sound | Jeff Carson | Music Editor |
| Sound | Brad Dechter | Orchestrator |
| Production | Cynthia Streit | Production Coordinator |
| Art | Kurt Volk | Title Designer |
| Crew | Larry Zanoff | Armorer |
| Art | Francois Larosa | Greensman |
| Writing | John Thomas | Characters |
| Production | Tom Proper | Associate Producer |
| Production | Bill Scott | Co-Producer |
| Crew | Tom Proper | Post Production Supervisor |
| Production | Ron Schmidt | Unit Production Manager |
| Directing | Susan Jasso | Second Second Assistant Director |
| Directing | David Rimer | Second Assistant Director |
| Crew | Troy Robinson | Stunts |
| Crew | Bob Brown | Stunts |
| Crew | Heidi Pascoe | Stunt Double |
| Crew | Tim Trella | Stunts |
