De film speelt zich af op de jungle-achtige thuisplaneet van de Predators. Op deze planeet huist ook een 'Mega-Predator' die elk jaar een groep van de gevaarlijkste individuen van de planeet aarde ontvoert, om ze vervolgens als prooi vrij te laten in de dodelijke jungle van de Predator-thuisplaneet. Royce (Adrien Brody) is de leider van een groepje huurlingen, dat onder andere bestaat uit een taaie vrouwelijke moordenaar, een man die totaal niet bang is om te sterven en een voormalige Russisch geheimagent. Samen moeten ze zien te overleven in de wildernis terwijl ze wanhopig proberen uit te vinden wat er met hen is gebeurd en door wie of wat ze worden opgejaagd...
Nee, helaas is Predators nog niet beschikbaar op Netflix in Nederland.
| Directing | Nimród Antal | Director |
| Writing | Alex Litvak | Writer |
| Production | J.C. Cantu | Casting |
| Writing | Michael Finch | Writer |
| Editing | Dan Zimmerman | Editor |
| Costume & Make-Up | Nina Proctor | Costume Design |
| Production | John Davis | Producer |
| Production | Robert Rodriguez | Producer |
| Production | Elizabeth Avellan | Producer |
| Sound | John Debney | Original Music Composer |
| Production | Mary Vernieu | Casting |
| Camera | Pados Gyula | Director of Photography |
| Production | Jaina Ashton | Casting |
| Production | Alex Young | Executive Producer |
| Crew | Heidi Pascoe | Stunt Double |
| Crew | Tim Trella | Stunts |
| Directing | Gina Grande | Script Supervisor |
| Sound | Tom Sturgis | Boom Operator |
| Sound | Clayton Weber | Foley Editor |
| Sound | David Bach | ADR Editor |
| Art | Richard J. Bell | Greensman |
| Sound | Carla Murray | Sound Designer |
| Sound | Angelo Palazzo | Sound Effects Editor |
| Art | Steve Joyner | Production Design |
| Art | Jeff B. Adams Jr. | Set Designer |
| Sound | Paula Fairfield | Sound Designer |
| Crew | Travis Smith | Visual Effects Editor |
| Writing | Jim Thomas | Characters |
| Art | Joe McCusker | Construction Coordinator |
| Art | Tommy Tomlinson | Property Master |
| Sound | Joaquin Gonzalo Avellán | Foley Editor |
| Costume & Make-Up | Ermahn Ospina | Makeup Department Head |
| Art | Adele Plauche | Set Designer |
| Sound | Tim Rakoczy | Supervising Sound Editor |
| Costume & Make-Up | Joe Rivera | Hair Department Head |
| Art | Ana Martínez | Art Department Coordinator |
| Sound | Brad Engleking | Dialogue Editor |
| Crew | Joe Montenegro | Special Effects Coordinator |
| Art | Caylah Eddleblute | Production Design |
| Sound | William Jacobs | Sound Editor |
| Directing | Brian Bettwy | First Assistant Director |
| Art | Pedro Barquin | Greensman |
| Art | David Hack | Set Decoration |
| Art | Mark Hanks | Leadman |
| Visual Effects | Jabbar Raisani | Visual Effects Supervisor |
| Visual Effects | Richard Wood | Special Effects Supervisor |
| Lighting | Jonathan Swartz | Lighting Director |
| Lighting | Colin J. Campbell | Gaffer |
| Camera | Neil Fraser | Dolly Grip |
| Costume & Make-Up | Amy Maner | Costume Supervisor |
| Art | Kurt Volk | Title Designer |
| Crew | Steve M. Davison | Stunt Coordinator |
| Camera | Mark Gerasimenko | Camera Operator |
| Costume & Make-Up | Cindy Renaud-Kim | Tailor |
| Camera | Henry Tirl | Steadicam Operator |
| Sound | Brad Dechter | Orchestrator |
| Lighting | Spencer Pharr | Lighting Technician |
| Camera | Ferrell A. Shinnick | Key Grip |
| Production | Logan Cooper | Location Manager |
| Sound | Jeff Carson | Music Editor |
| Crew | Larry Zanoff | Armorer |
| Crew | Jeff 'JJ' Dashnaw | Stunt Coordinator |
| Camera | Rico Torres | Still Photographer |
| Production | Cynthia Streit | Production Coordinator |
| Crew | Hank Amos | Stunts |
| Crew | Norman Mora | Stunts |
| Crew | Ryan Happy | Stunts |
| Crew | Steve Boyles | Stunts |
| Crew | Joey Anaya | Stunts |
| Crew | Jon Sakata | Stunts |
| Crew | James C. Lewis | Stunts |
| Crew | Jeremy Fitzgerald | Stunts |
| Crew | Dana Reed | Stunts |
| Crew | James Ryan | Stunts |
| Crew | Brian Keaulana | Stunts |
| Crew | Brian Munce | Stunts |
| Crew | Michael Hansen | Stunts |
| Crew | Ryan Ryusaki | Stunts |
| Crew | David Schultz | Stunts |
| Crew | Aaron Walters | Stunts |
| Crew | Dick Hancock | Stunts |
| Art | Francois Larosa | Greensman |
| Crew | Troy Robinson | Stunts |
| Crew | Bob Brown | Stunts |
| Production | Bill Scott | Co-Producer |
| Production | Tom Proper | Associate Producer |
| Writing | John Thomas | Characters |
| Production | Ron Schmidt | Unit Production Manager |
| Crew | Tom Proper | Post Production Supervisor |
| Directing | Susan Jasso | Second Second Assistant Director |
| Directing | David Rimer | Second Assistant Director |
| Visual Effects | Jan Philip Cramer | Animation Supervisor |
| Editing | Mo Henry | Negative Cutter |
| Visual Effects | Charles Tait | Compositing Artist |