Ash en zijn vrienden zijn uitgenodigd op een groot festival, waar gevierd wordt dat lang geleden held Sir Aaron en zijn Pokémon Lucario de wereld hebben gered van de ondergang door gebruik te maken van de krachten van een Magische Boom. Ash en Pikachu winnen de Pokémon wedstrijd, krijgen de titel 'Beschermer van Aura' en mogen de staf van Sir Aaron voor een avond vasthouden. De staf waarvan men denkt dat de verdwenen Pokémon Lucario er al jaren in gevangen zit. Maar de feestvreugde is snel voorbij als de mysterieuze Pokemon Mew opduikt en Pikachu meeneemt. Op datzelfde moment weet Lucario uit de staf van Sir Aaron te ontsnappen. Met hulp van Lucario gaat Ash op zoek naar de Magische Boom en de legendarische Pokémon Mew. De toekomst van de wereld hangt nu af van de hechte vriendschap tussen mensen en Pokémons.
Nee, helaas is Pokémon: Lucario en het Mysterie van Mew nog niet beschikbaar op Netflix in Nederland.
| Directing | 湯山邦彦 | Director |
| Visual Effects | 佐藤美由紀 | Color Designer |
| Art | 湯山邦彦 | Storyboard Artist |
| Art | 増井壮一 | Storyboard Artist |
| Art | 浅田裕二 | Storyboard Artist |
| Art | 宮尾佳和 | Storyboard Artist |
| Art | 木村哲 | Storyboard Artist |
| Visual Effects | 松本卓也 | Animation Director |
| Sound | 吉村由美 | Songs |
| Sound | 大貫亜美 | Songs |
| Visual Effects | Shiro Kudaka | Key Animation |
| Visual Effects | Tsuneo Ninomiya | Key Animation |
| Visual Effects | 吉田大輔 | Key Animation |
| Visual Effects | 佐藤陵 | Key Animation |
| Visual Effects | 竹渕正美 | Key Animation |
| Visual Effects | 井坂純子 | Key Animation |
| Visual Effects | 中村亜貴子 | Key Animation |
| Visual Effects | 宮田忠明 | Key Animation |
| Visual Effects | 渡辺敦子 | Key Animation |
| Visual Effects | Midori Nagaoka | Key Animation |
| Visual Effects | 小林ゆかり | Key Animation |
| Visual Effects | Hideki Takahashi | Key Animation |
| Visual Effects | 武井智子 | Key Animation |
| Crew | 増田順一 | Creator |
| Production | 石原恒和 | Production Supervisor |
| Visual Effects | 小田部羊一 | Animation Supervisor |
| Production | 鶴宏明 | Executive Producer |
| Production | 神田修吉 | Producer |
| Production | Yukako Matsusako | Producer |
| Directing | 浅田裕二 | Assistant Director |
| Production | 岡本順哉 | Producer |
| Writing | 園田英樹 | Screenplay |
| Production | 久保雅一 | Executive Producer |
| Production | 吉川兆二 | Producer |
| Production | 奥野敏聡 | Producer |
| Crew | 杉森建 | Creator |
| Crew | 田尻智 | Creator |
| Production | 盛武源 | Producer |
| Editing | Mizue Ueda | Colorist |
| Directing | 吉川博明 | Assistant Director |
| Directing | 渡辺正彦 | Assistant Director |
| Sound | 三間雅文 | Sound Director |
| Visual Effects | 一石小百合 | Character Designer |
| Visual Effects | 高橋美香 | Animation Director |
| Camera | Takuya Mizutani | Director of Photography |
| Directing | 高橋ナオヒト | Assistant Director |
| Visual Effects | 玉川明洋 | Animation Director |
| Editing | 辺見俊夫 | Editor |
| Visual Effects | Senri Ikehara | Animation Director |
| Visual Effects | Tokuhiro Matsubara | Character Designer |
| Visual Effects | 毛利和昭 | Animation Director |
| Visual Effects | 君塚勝教 | Animation Director |
| Visual Effects | 毛利和昭 | Character Designer |
| Visual Effects | 志村隆行 | Animation Director |
| Visual Effects | 井ノ上ユウ子 | Animation Director |
| Editing | 上村貴子 | Colorist |
| Directing | Yumi Kamakura | Assistant Director |
| Directing | 飯島正勝 | Assistant Director |
| Visual Effects | 夏目久仁彦 | Animation Director |
| Sound | Kazuo Shinohara | Music Producer |
| Sound | Yuji Saito | Music Producer |
| Visual Effects | 相澤昌弘 | Animation Director |
| Art | 武藤正敏 | Art Direction |
| Sound | 宮崎慎二 | Music |
| Writing | 田尻智 | Original Story |
