Ash en zijn vrienden zijn uitgenodigd op een groot festival, waar gevierd wordt dat lang geleden held Sir Aaron en zijn Pokémon Lucario de wereld hebben gered van de ondergang door gebruik te maken van de krachten van een Magische Boom. Ash en Pikachu winnen de Pokémon wedstrijd, krijgen de titel 'Beschermer van Aura' en mogen de staf van Sir Aaron voor een avond vasthouden. De staf waarvan men denkt dat de verdwenen Pokémon Lucario er al jaren in gevangen zit. Maar de feestvreugde is snel voorbij als de mysterieuze Pokemon Mew opduikt en Pikachu meeneemt. Op datzelfde moment weet Lucario uit de staf van Sir Aaron te ontsnappen. Met hulp van Lucario gaat Ash op zoek naar de Magische Boom en de legendarische Pokémon Mew. De toekomst van de wereld hangt nu af van de hechte vriendschap tussen mensen en Pokémons.
Nee, helaas is Pokémon: Lucario en het Mysterie van Mew nog niet beschikbaar op Netflix in Nederland.
| Directing | 湯山邦彦 | Director |
| Visual Effects | 佐藤美由紀 | Color Designer |
| Art | 宮尾佳和 | Storyboard Artist |
| Art | 増井壮一 | Storyboard Artist |
| Art | 湯山邦彦 | Storyboard Artist |
| Art | 木村哲 | Storyboard Artist |
| Art | 浅田裕二 | Storyboard Artist |
| Visual Effects | 松本卓也 | Animation Director |
| Sound | 吉村由美 | Songs |
| Sound | 大貫亜美 | Songs |
| Visual Effects | 武井智子 | Key Animation |
| Visual Effects | 井坂純子 | Key Animation |
| Visual Effects | 佐藤陵 | Key Animation |
| Visual Effects | Hideki Takahashi | Key Animation |
| Visual Effects | Midori Nagaoka | Key Animation |
| Visual Effects | 吉田大輔 | Key Animation |
| Visual Effects | 竹渕正美 | Key Animation |
| Visual Effects | Shiro Kudaka | Key Animation |
| Visual Effects | 中村亜貴子 | Key Animation |
| Visual Effects | 宮田忠明 | Key Animation |
| Visual Effects | 渡辺敦子 | Key Animation |
| Visual Effects | 小林ゆかり | Key Animation |
| Visual Effects | Tsuneo Ninomiya | Key Animation |
| Crew | 増田順一 | Creator |
| Production | 石原恒和 | Production Supervisor |
| Directing | 渡辺正彦 | Assistant Director |
| Sound | 宮崎慎二 | Music |
| Production | Hiroaki Tsuru | Executive Producer |
| Visual Effects | 井ノ上ユウ子 | Animation Director |
| Editing | Mizue Ueda | Colorist |
| Production | 久保雅一 | Executive Producer |
| Visual Effects | 毛利和昭 | Character Designer |
| Camera | Takuya Mizutani | Director of Photography |
| Sound | Kazuo Shinohara | Music Producer |
| Visual Effects | Senri Ikehara | Animation Director |
| Editing | 辺見俊夫 | Editor |
| Production | 神田修吉 | Producer |
| Directing | 吉川博明 | Assistant Director |
| Production | 吉川兆二 | Producer |
| Production | 岡本順哉 | Producer |
| Directing | 飯島正勝 | Assistant Director |
| Directing | Yumi Kamakura | Assistant Director |
| Visual Effects | Tokuhiro Matsubara | Character Designer |
| Visual Effects | 毛利和昭 | Animation Director |
| Crew | 田尻智 | Creator |
| Production | Yukako Matsusako | Producer |
| Visual Effects | 相澤昌弘 | Animation Director |
| Visual Effects | 高橋美香 | Animation Director |
| Editing | 上村貴子 | Colorist |
| Writing | 園田英樹 | Screenplay |
| Visual Effects | 志村隆行 | Animation Director |
| Visual Effects | 君塚勝教 | Animation Director |
| Art | 武藤正敏 | Art Direction |
| Production | 盛武源 | Producer |
| Directing | 浅田裕二 | Assistant Director |
| Visual Effects | 一石小百合 | Character Designer |
| Sound | Yuji Saito | Music Producer |
| Production | 奥野敏聡 | Producer |
| Sound | 三間雅文 | Sound Director |
| Visual Effects | 小田部羊一 | Animation Supervisor |
| Directing | 高橋ナオヒト | Assistant Director |
| Visual Effects | 玉川明洋 | Animation Director |
| Crew | 杉森建 | Creator |
| Visual Effects | 夏目久仁彦 | Animation Director |
| Writing | 田尻智 | Original Story |
