Dr. Lawrence Gordon en Adam, twee mannen die elkaar nooit eerder hebben gezien, ontwaken vastgebonden in een smerige, oude badkamer.
| Sound | Charlie Clouser | Original Music Composer |
| Production | Gregg Hoffman | Producer |
| Editing | Kevin Greutert | Editor |
| Production | Amy Lippens | Casting |
| Camera | David A. Armstrong | Director of Photography |
| Directing | James Wan | Director |
| Production | Mark Burg | Producer |
| Production | Oren Koules | Producer |
| Sound | Jonathan Miller | Sound Designer |
| Writing | Leigh Whannell | Writer |
| Costume & Make-Up | Eleanor Sabaduquia | Makeup Department Head |
| Costume & Make-Up | Jennifer L. Soulages | Costume Design |
| Art | Nanet Harty | Art Direction |
| Art | Julie Berghoff | Production Design |
| Sound | Jonathan Miller | Supervising Sound Editor |
| Production | Jason Constantine | Executive Producer |
| Production | Richard H. Prince | Co-Producer |
| Production | Lark Bernini | Associate Producer |
| Production | Stacey Testro | Executive Producer |
| Production | Peter Block | Executive Producer |
| Production | Daniel J. Heffner | Co-Producer |
| Writing | Leigh Whannell | Story |
| Writing | James Wan | Story |
| Costume & Make-Up | Rocky Faulkner | Prosthetic Supervisor |
| Editing | Andrew Patterson | Dialogue Editor |
| Costume & Make-Up | Scott H. Eddo | Makeup Artist |
| Crew | Tory Mell | Set Production Assistant |
| Editing | Dan Muscarella | Color Timer |
| Lighting | Thomas Kuo | Electrician |
| Camera | Greg Gayne | Still Photographer |
| Crew | Summer Ramsey | Scenic Artist |
| Lighting | Bill Persaud | Rigging Grip |
| Production | Monica Muehlhause-Horn | Production Accountant |
| Camera | Chris Gordon | Grip |
| Visual Effects | Thomas L. Bellissimo | Special Effects Supervisor |
| Visual Effects | Mark Allan | Visual Effects Coordinator |
| Visual Effects | Andrew Midgley | Visual Effects Producer |
| Visual Effects | Marlo Pabon | Visual Effects Supervisor |
| Camera | Josh Harrison | First Assistant Camera |
| Camera | Oscar Garcia | Key Grip |
| Production | Richard H. Prince | Production Manager |
| Crew | Timothy Feimster | Carpenter |
| Crew | Martin Glover | Video Assist Operator |
| Production | Vicky Choy | Production Coordinator |
| Crew | Tricia Sherwood | Craft Service |
| Directing | Jillian Giacomini | Script Supervisor |
| Lighting | Yaron Levy | Gaffer |
| Sound | Jonathan Scott Miller | Music Supervisor |
| Directing | Daniel J. Heffner | First Assistant Director |
| Production | Jennifer Levy | Casting Associate |
| Sound | Randy Babajtis | Sound Effects Editor |
| Art | Jill Bream | Art Department Assistant |
| Camera | Lisa Villaire | Camera Loader |
| Art | Bill Davis | Property Master |
| Costume & Make-Up | Michelle Rene Elam | Key Hair Stylist |
| Sound | Cameron Allan | Music Editor |
| Sound | John Taylor | Sound Mixer |
| Crew | Ian Elias | Post Production Assistant |
| Crew | Chuck Radtke | Production Intern |
| Costume & Make-Up | Kathleen Russo | Costume Supervisor |
| Costume & Make-Up | Kashka Banjoko | Hairstylist |
| Sound | Speed Ratliff | Boom Operator |
| Visual Effects | Derek Bird | Digital Compositors |
| Crew | Keith Adams | Stunt Coordinator |
| Lighting | Brandon Cunningham | Best Boy Electric |
| Lighting | Ray Skinner | Electrician |
| Camera | Jon Myers | Camera Operator |
| Camera | Andy Steinman | Second Unit Director of Photography |
| Art | Robert Beebe | Title Designer |
| Art | Luis A. Arevalos | Swing |
| Costume & Make-Up | Christina DeMasi | Costumer |
| Sound | Shelley Roden | Foley Artist |
| Editing | John Coniglio | Assistant Editor |
| Sound | Rebecca Rienks | Music Coordinator |
| Production | Alexis Ross | Production Assistant |
| Crew | Charles Belardinelli | Special Effects Assistant |
| Camera | John Loveall | Best Boy Grip |
| Editing | Mark Griffith | Digital Intermediate Colorist |
| Production | Kenny Selko | Key Set Production Assistant |
| Sound | Eric Gorfain | Music Arranger |
| Sound | Jeremy Balko | Foley Mixer |
| Crew | Mocean Melvin | Stunt Driver |
| Camera | Todd Baldi | Second Assistant Camera |
| Camera | Michael Steffen | Dolly Grip |
| Production | Lisa S. Beasley | Extras Casting |
| Production | Alex Franklin | Production Secretary |
| Sound | Alan Freedman | ADR Mixer |
| Production | Sherry Kecskes | Assistant Accountant |
| Art | Jeffrey Reyes | Assistant Property Master |
| Costume & Make-Up | Richard Redlefsen | Assistant Makeup Artist |
| Art | Jake Blecha | Swing |
| Directing | Alexa Sheehan | Second Assistant Director |
