Marley is een gele labrador die door John Grogan, een columnist voor een krant, en zijn vrouw Jennifer wordt geadopteerd. Het idee was om zo een idee te krijgen wat ouderschap inhoudt, maar de hond blijkt nogal hyperactief te zijn. Hij vernielt de boel, wordt van de gehoorzaamheidsschool geschopt en wordt alleen maar erger wanneer John en Jennifer kinderen krijgen.
Nee, helaas is Marley & Me nog niet beschikbaar op Netflix in Nederland.
| Directing | David Frankel | Director |
| Writing | Scott Frank | Screenplay |
| Writing | Don Roos | Screenplay |
| Sound | Marko Costanzo | Foley Artist |
| Sound | Theodore Shapiro | Original Music Composer |
| Production | Gil Netter | Producer |
| Production | Karen Rosenfelt | Producer |
| Camera | Florian Ballhaus | Director of Photography |
| Editing | Mark Livolsi | Editor |
| Production | Margery Simkin | Casting |
| Costume & Make-Up | Cindy Evans | Costume Design |
| Sound | Julia Michels | Music Supervisor |
| Art | Stuart Wurtzel | Production Design |
| Production | Arnon Milchan | Executive Producer |
| Production | Joseph M. Caracciolo Jr. | Executive Producer |
| Writing | John Grogan | Book |
| Production | Joseph M. Caracciolo Jr. | Unit Production Manager |
| Production | Dana Robin | Unit Production Manager |
| Crew | G.A. Aguilar | Stunt Coordinator |
| Crew | John Cenatiempo | Stunt Coordinator |
| Crew | Blaise Corrigan | Stunt Coordinator |
| Camera | Thomas Lappin | Camera Operator |
| Camera | Bob Gorelick | Camera Operator |
| Camera | Bob Gorelick | Steadicam Operator |
| Crew | April Ruane Crowley | Loader |
| Camera | Barry Wetcher | Still Photographer |
| Directing | Sheila Waldron | Script Supervisor |
| Editing | David Rogow | Additional Editing |
| Editing | William Kruzykowski | Assistant Editor |
| Editing | Gina Sansom | Editorial Production Assistant |
| Sound | Thomas S. Drescher | Music Editor |
| Sound | Joe Foglia | Sound Mixer |
| Sound | Kevin Santy | Boom Operator |
| Crew | Michael Pisano | Cableman |
| Art | W. Steven Graham | Art Direction |
| Art | Mario Ventenilla | Assistant Art Director |
| Art | John Pollard | Assistant Art Director |
| Art | Hilton Rosemarin | Set Decoration |
| Art | Cedar Valentine | Art Department Coordinator |
| Lighting | Jeff Murrell | Gaffer |
| Lighting | Steve Reinhardt | Best Boy Electric |
| Lighting | Jack H. Rose, II | Best Boy Electric |
| Lighting | Dennis J. Lootens | Rigging Gaffer |
| Costume & Make-Up | Patricia McLaughlin | Costume Supervisor |
| Costume & Make-Up | Brooke Fein | Set Costumer |
| Costume & Make-Up | Sue Salzano | Set Costumer |
| Costume & Make-Up | Felice Diamond | Makeup Department Head |
| Costume & Make-Up | Angela Levin | Makeup Artist |
| Costume & Make-Up | Tina Earnshaw | Makeup Artist |
| Costume & Make-Up | Caridad Collazo | Key Hair Stylist |
| Costume & Make-Up | Chris McMillan | Hairstylist |
| Costume & Make-Up | Kelsie Gigandet | Hairstylist |
| Costume & Make-Up | Geraldine Jones | Hairstylist |
| Production | Ellen Gannon | Production Coordinator |
| Crew | J.C. Brotherhood | Special Effects Coordinator |
| Art | Ron Petagna Sr. | Construction Coordinator |
| Production | Lori Scowley | Production Accountant |
| Production | Justine Hempe | Casting Associate |
| Production | Gayle Keller | Casting |
| Production | Lori Wyman | Casting |
| Production | Danielle Colli | Casting Associate |
| Crew | Linda Colangelo | Unit Publicist |
| Crew | Edward O'Donnell | Transportation Captain |
| Crew | Tommy McGoldrick | Transportation Co-Captain |
| Crew | Cyril O'Neil | Picture Car Coordinator |
| Crew | Ray Rifice | Video Assist Operator |
| Visual Effects | Todd A. Marks | 24 Frame Playback |
| Crew | Marc H. Katz | Craft Service |
| Visual Effects | Ray McIntyre Jr. | Visual Effects Supervisor |
| Visual Effects | Victor DiMichina | Visual Effects Producer |
| Sound | Paul Urmson | Supervising Sound Editor |
| Sound | Nicholas Renbeck | Supervising Sound Editor |
| Sound | Wyatt Sprague | Sound Effects Editor |
| Sound | Tom Fleischman | Sound Re-Recording Mixer |
| Production | Sam Tedesco | Location Manager |
| Directing | Donald Dowd | Assistant Director |
| Crew | Billy Bates | Stunt Driver |
| Crew | Chick Bernhard | Stunt Driver |
| Crew | Rosie Bernhard | Stunt Driver |
| Crew | Stacy Courtney | Stunt Double |
| Crew | Cort Hessler | Stunt Driver |
| Crew | Howard S. Lefstein | Stunt Double |
| Crew | Joni Podesta | Stunt Double |
| Crew | Nancy Wetzel | Stunt Driver |
| Crew | Paul Marini | Stunts |
| Art | Philip Schneider | Property Master |
| Art | Tracey Wilson | Storyboard Artist |