Sidney Young is een gedesillusioneerde intellectueel die werkt bij een klein tijdschrift. Omdat hij een hekel heeft aan het leven van de glamour en roem in Hollywood, wordt hij opgemerkt door een groter publiek, omdat hij hier juist stukken over schrijft. Al snel wordt hij aangenomen bij een groter tijdschrift, waar hij zichzelf alles behalve geliefd maakt.
Nee, helaas is How to Lose Friends & Alienate People nog niet beschikbaar op Netflix in Nederland.
| Production | Jon Diamond | Executive Producer |
| Production | Stephen Woolley | Producer |
| Production | Jimmy Price | Line Producer |
| Production | Paul White | Executive Producer |
| Production | Peter Hampden | Executive Producer |
| Production | Norman Merry | Executive Producer |
| Production | Kim Davis-Wagner | Casting |
| Art | John Beard | Production Design |
| Directing | Robert B. Weide | Director |
| Production | Elizabeth Karlsen | Producer |
| Editing | David Freeman | Editor |
| Production | Toby Young | Producer |
| Production | Justine Arteta | Casting |
| Camera | Oliver Stapleton | Director of Photography |
| Production | Robin O'Hara | Producer |
| Production | Lila Yacoub | Line Producer |
| Production | Carrie Fix | Line Producer |
| Production | Jina Jay | Casting |
| Production | Gary Smith | Executive Producer |
| Writing | Peter Straughan | Screenplay |
| Production | Tessa Ross | Executive Producer |
| Production | Brian Gilmore | Executive Producer |
| Sound | David Arnold | Original Music Composer |
| Production | Simon Fawcett | Executive Producer |
| Production | Richard Hewitt | Line Producer |
| Art | Anthony Gasparro | Art Direction |
| Art | Sara Parks | Set Decoration |
| Costume & Make-Up | Annie Hardinge | Costume Design |
| Crew | Jo Fernihough | Unit Publicist |
| Directing | Beverly Winston | Script Supervisor |
| Crew | Polly Duval | Post Production Supervisor |
| Writing | Toby Young | Script Consultant |
| Production | Tony Clarkson | Location Manager |
| Production | Neil Chaplin | Production Accountant |
| Sound | Jim Greenhorn | Sound Mixer |
| Directing | Matthew Penry-Davey | First Assistant Director |
| Sound | Orin Beaton | Boom Operator |
| Camera | Rupert Lloyd-Parry | Key Grip |
| Camera | John Jordan | Focus Puller |
| Camera | Andrew Jones | Camera Trainee |
| Writing | Toby Young | Book |
| Sound | Glenn Freemantle | Supervising Sound Editor |
| Directing | Lance Roehrig | Second Assistant Director |
| Production | Ella Harris | Production Runner |
| Production | Hollie Foster | Assistant Production Coordinator |
| Crew | Ryan Taggart | Loader |
| Directing | Simon Downes | Second Second Assistant Director |
| Directing | Charlie Reed | Third Assistant Director |
| Crew | Sam Haveland | Floor Runner |
| Crew | Robert Hamilton | Video Assist Operator |
| Production | Susan Chika Anisiobi | Assistant Accountant |
| Production | Joanna Laurie | Producer's Assistant |
| Sound | Nadine Richardson | Sound Assistant |
| Camera | Pete Cavaciuti | Steadicam Operator |
| Crew | Philip James Booth | Stand In |
| Production | Sarah Stiff | Assistant Accountant |
| Production | Francesca Dowd | Production Coordinator |
| Production | Peter Ogunsalu | Producer's Assistant |
| Crew | Loyd Catlett | Actor's Assistant |
| Crew | Liat Baruch | Actor's Assistant |
| Production | Robin Davies | Producer's Assistant |
| Crew | Hannah Andrews | Stand In |
| Art | Ray Fisher | Leadman |
| Art | Ray Chan | Supervising Art Director |
| Production | Laurie Borg | Co-Producer |
| Crew | Jo McLaren | Stunt Double |
| Costume & Make-Up | Nana Fischer | Makeup Artist |
| Costume & Make-Up | Lucy Sibbick | Makeup Artist |
| Sound | Hugo Adams | Foley Editor |
| Sound | Niv Adiri | Sound |
| Sound | Ed Colyer | Foley Mixer |
| Sound | Glen Gathard | Assistant Foley Artist |