Professor Sherman Klump probeert een wit voetje te halen bij zijn nieuwe collega Denise. Na een mislukt DNA-experiment worden Sherman en zijn alter ego Buddy Love van elkaar gescheiden. Een catastrofe voor de brave Sherman die elementen uit Denises onderzoek nodig heeft om voor eens en altijd af te rekenen met Buddy Love.
Nee, helaas is The Nutty Professor II: The Klumps nog niet beschikbaar op Netflix in Nederland.
| Production | James D. Brubaker | Executive Producer |
| Editing | William Kerr | Editor |
| Production | Brian Grazer | Producer |
| Writing | David Sheffield | Screenplay |
| Production | Eddie Murphy | Executive Producer |
| Writing | Paul Weitz | Screenplay |
| Production | Jerry Lewis | Executive Producer |
| Directing | Peter Segal | Director |
| Production | Tom Shadyac | Executive Producer |
| Writing | Chris Weitz | Screenplay |
| Camera | Dean Semler | Director of Photography |
| Production | Karen Kehela Sherwood | Executive Producer |
| Writing | Barry W. Blaustein | Screenplay |
| Sound | Dave Jordan | Music Coordinator |
| Costume & Make-Up | Kazu Hiro | Makeup Designer |
| Sound | David Newman | Original Music Composer |
| Writing | David Sheffield | Story |
| Writing | Barry W. Blaustein | Story |
| Writing | Jerry Lewis | Characters |
| Writing | Steve Oedekerk | Story |
| Production | Jim Whitaker | Co-Producer |
| Sound | Happy Walters | Music Supervisor |
| Costume & Make-Up | Sharen Davis | Costume Design |
| Sound | Gary Jones | Music Supervisor |
| Production | Michael Ewing | Co-Producer |
| Crew | Alan Oliney | Stunt Coordinator |
| Directing | Susan Bierbaum | Script Supervisor |
| Costume & Make-Up | Rick Baker | Special Effects Makeup Artist |
| Production | Arlene Kehela | Associate Producer |
| Visual Effects | Jon Farhat | Visual Effects Supervisor |
| Sound | Jonathan Fuh | Boom Operator |
| Crew | Mickey Gilbert | Stunt Coordinator |
| Camera | Bruce McBroom | Still Photographer |
| Crew | Bronwyn Preston | Unit Publicist |
| Crew | Greg Salmon | Cableman |
| Camera | Joseph D. Urbanczyk | Camera Operator |
| Costume & Make-Up | Nena Smarz | Makeup Department Head |
| Art | Greg Papalia | Art Direction |
| Art | John H. Anderson | Set Decoration |
| Sound | José Antonio García | Sound Mixer |
| Art | William A. Elliott | Production Design |
| Writing | Zak Penn | Writer |
| Art | Douy Swofford | Title Designer |