Na vijf jaar komt Billy Brown vrij uit de gevangenis. Hij neemt zich voor om twee dingen te doen: zijn ouders bezoeken, die al die tijd dachten dat hij gelukkig getrouwd was en een leuke job had, en de football speler om het leven brengen die vijf jaar voordien the Bills de Super Bowl heeft doen verliezen en dus ook Billy's weddenschap de mist heeft doen ingaan.
Nee, helaas is Buffalo 66 nog niet beschikbaar op Netflix in Nederland.
| Directing | Vincent Gallo | Director |
| Writing | Vincent Gallo | Screenplay |
| Writing | Alison Bagnall | Screenplay |
| Production | Chris Hanley | Producer |
| Camera | Lance Acord | Director of Photography |
| Editing | Curtiss Clayton | Editor |
| Costume & Make-Up | Lynn Campbell | Makeup Artist |
| Costume & Make-Up | Michael Kriston | Hairstylist |
| Costume & Make-Up | Rachel Kregal | Set Costumer |
| Art | Gideon Ponte | Production Design |
| Art | James Chinlund | Art Direction |
| Art | Jeanne Develle | Set Decoration |
| Costume & Make-Up | Alexis Scott | Costume Design |
| Sound | Rick Ash | Sound Re-Recording Mixer |
| Sound | Hamilton Sterling | Sound Editor |
| Sound | Vincent Gallo | Original Music Composer |
| Production | Vincent Gallo | Producer |
| Production | Michael Paseornek | Executive Producer |
| Production | Jeff Sackman | Executive Producer |
| Crew | Toshiaki Ozawa | Lighting Camera |
| Editing | Hilary Schroeder | Assistant Editor |
| Directing | Catherine Gore | Script Supervisor |
| Production | Jordan Gertner | Co-Producer |
| Production | Deborah Brock | Co-Producer |
| Production | John Dunning | Executive Producer |
| Production | André Link | Executive Producer |
| Directing | Jennifer Gerould | Second Assistant Director |
| Directing | Michaelangelo Bolla | First Assistant Director |
| Camera | John Clemens | First Assistant Camera |
| Sound | Brian Miksis | Production Sound Mixer |
| Production | Janet Gallo | Associate Producer |
| Production | Lauren Buckley | Associate Producer |
| Production | Timothy Wayne Peternel | Associate Producer |
| Crew | Josephine Colangelo | In Memory Of |
| Crew | Anthony Fantuzzo | In Memory Of |
| Crew | Marie Morreale | In Memory Of |
| Directing | Adam Greenhaus | Second Unit Director |
| Writing | Vincent Gallo | Story |
| Lighting | Toshiaki Ozawa | Gaffer |
| Production | Avram Butch Kaplan | Unit Production Manager |
| Sound | Allen Hartz | Dialogue Editor |
| Sound | Thom Brennan | Foley Editor |
| Production | Robert Pfeffer | Accountant |
| Camera | Gino Nix | Key Grip |
| Production | Lauren Buckley | Associate Producer |
| Crew | Tim Oravetz | Propmaker |
