Een team van ontdekkingsreizigers gaat op een reis door het universum waarbij ze een ontdekking doen die leidt naar de oorsprong van het ontstaan van de mensheid. Hierdoor belanden ze in de gevaarlijkste uithoeken van het universum. Daar zullen ze een angstaanjagend gevecht moeten doorstaan om de toekomst van de mensheid te redden.
| Art | H. R. Giger | Art Direction |
| Directing | Ridley Scott | Director |
| Sound | Marc Streitenfeld | Original Music Composer |
| Camera | Dariusz Wolski | Director of Photography |
| Editing | Pietro Scalia | Editor |
| Production | Nina Gold | Casting |
| Production | Avy Kaufman | Casting |
| Art | Arthur Max | Production Design |
| Art | Sonja Klaus | Set Decoration |
| Costume & Make-Up | Janty Yates | Costume Design |
| Production | Ridley Scott | Producer |
| Production | Walter Hill | Producer |
| Production | Michael Costigan | Executive Producer |
| Production | Mark Huffam | Executive Producer |
| Production | Michael Ellenberg | Executive Producer |
| Writing | Jon Spaihts | Writer |
| Production | Damon Lindelof | Executive Producer |
| Writing | Damon Lindelof | Writer |
| Art | Alex Cameron | Art Direction |
| Art | Anthony Caron-Delion | Art Direction |
| Art | Peter Dorme | Art Direction |
| Art | Marc Homes | Art Direction |
| Art | Paul Inglis | Art Direction |
| Art | Karen Wakefield | Art Direction |
| Art | Laura Davison | Construction Coordinator |
| Art | Sarah Griggs | Art Department Coordinator |
| Art | Philip Elton | Assistant Art Director |
| Art | Tom Whitehead | Assistant Art Director |
| Art | Tom Weaving | Assistant Art Director |
| Art | Helen Xenopoulos | Assistant Art Director |
| Crew | James Newell | Scenic Artist |
| Art | Claudio Campana | Assistant Art Director |
| Sound | Victor Ray Ennis | Supervising Sound Editor |
| Sound | John T. Cucci | Foley |
| Sound | Dan O'Connell | Foley |
| Sound | Mark P. Stoeckinger | Supervising Sound Editor |
| Visual Effects | Trent Claus | Visual Effects Supervisor |
| Visual Effects | Jamie Dixon | Visual Effects Supervisor |
| Visual Effects | Dick Edwards | Visual Effects Supervisor |
| Visual Effects | Martin Hill | Visual Effects Supervisor |
| Visual Effects | Annette Wullems | Visual Effects Producer |
| Visual Effects | Allen Maris | Visual Effects Producer |
| Visual Effects | Michelle Eisenreich | Visual Effects Producer |
| Crew | Rob Inch | Stunt Coordinator |
| Camera | Kerry Brown | Still Photographer |
| Lighting | Perry Evans | Gaffer |
| Camera | Graham Hall | Camera Operator |
| Camera | Daniele Massaccesi | Camera Operator |
| Camera | Daniele Massaccesi | Steadicam Operator |
| Camera | David Morgan | Camera Operator |
| Camera | Gary Spratling | Camera Operator |
| Costume & Make-Up | Gordon Harmer | Costume Supervisor |
| Costume & Make-Up | Calandra Meredith | Set Costumer |
| Costume & Make-Up | Georgiana Sayer | Set Costumer |
| Costume & Make-Up | Bruno de Santa | Set Costumer |
| Sound | Joseph Bonn | Music Editor |
| Sound | Del Spiva | Music Editor |
| Crew | Peter Devlin | Transportation Coordinator |
| Directing | Amal Baggar | Script Coordinator |
| Crew | Catherine Charlton | Dialect Coach |
| Production | Steve Hart | Location Manager |
| Directing | Annie Penn | Script Supervisor |
| Sound | Doug Hemphill | Sound Re-Recording Mixer |
| Sound | Ron Bartlett | Sound Re-Recording Mixer |
| Crew | Michael Queen | Compositors |
| Production | David Giler | Producer |
| Crew | Mike Potter | Stunts |
| Sound | Kirsty Whalley | Music Editor |
| Production | Miranda Marks | Production Coordinator |
| Costume & Make-Up | Jana Carboni | Makeup Artist |
| Costume & Make-Up | Aisling Nairn | Makeup Artist |
| Costume & Make-Up | Nicky Knowles | Hairstylist |
| Costume & Make-Up | Nana Fischer | Hair Designer |
| Costume & Make-Up | Enzo Angileri | Hair Designer |
| Costume & Make-Up | Peta Dunstall | Hairstylist |
| Art | John King | Supervising Art Director |
| Visual Effects | Ferran Domenech | Animation Supervisor |
| Sound | Simon Hayes | Production Sound Mixer |
| Art | David Vyle Levy | Conceptual Design |
| Lighting | Simon Dutton | Rigging Supervisor |
| Costume & Make-Up | Davide Losi | Prosthetics |
| Lighting | Mark 'Rocky' Evans | Electrician |
| Sound | Tim Gomillion | Sound Recordist |
| Sound | Dennis Rogers | Sound Recordist |
| Sound | Margit Pfeiffer | Dialogue Editor |
| Sound | Michael Hertlein | Dialogue Editor |
| Sound | Julie Feiner | Dialogue Editor |
| Sound | Daniel S. Irwin | Supervising Dialogue Editor |
| Visual Effects | Richard Stammers | Visual Effects Supervisor |
| Visual Effects | Trevor Wood | Visual Effects Supervisor |
| Visual Effects | Charley Henley | Visual Effects Supervisor |
| Art | Neville Page | Concept Artist |
| Directing | Max Keene | First Assistant Director |
| Writing | Dan O'Bannon | Characters |
| Writing | Ronald Shusett | Characters |
| Visual Effects | Paul Butterworth | Visual Effects Designer |
| Directing | Carolina Jiménez | Layout |
| Visual Effects | Maher Asaad Baker | Visual Effects |
| Art | Archie Campbell-Baldwin | Art Department Assistant |
| Crew | Rowley Irlam | Stunts |
| Costume & Make-Up | Maggie Partington-Smith | Costume Assistant |
| Costume & Make-Up | Angela Pledge | Costume Assistant |
| Art | Glenn Marsh | Sculptor |
| Visual Effects | Lisa Gonzalez | Visual Effects Supervisor |
| Sound | Glenn T. Morgan | Foley Editor |
| Sound | Glen Gathard | ADR Recordist |
| Camera | Stephen Smart | Data Wrangler |
| Lighting | Jim Smart | Electrician |
| Art | Julian Caldow | Production Illustrator |
| Visual Effects | Julian Bryant | Digital Compositor |
| Art | Rebecca White | Art Department Assistant |
| Crew | Phillip Leonhardt | CG Supervisor |
| Lighting | David Sinfield | Best Boy Electric |
| Sound | Ben Foster | Conductor |
| Art | Andrew Palmer | Assistant Art Director |
| Visual Effects | Jason Lei Howden | Rotoscoping Artist |
| Visual Effects | Charles Tait | Compositing Supervisor |
| Costume & Make-Up | Chris Lyons | Special Effects Makeup Artist |
| Costume & Make-Up | Nathaniel De'Lineadeus | Special Effects Makeup Artist |
| Costume & Make-Up | Alex Rouse | Wigmaker |
