Cady Heron is nieuw op school en wordt toegelaten tot de top van de sociale voedselketen: het elitegroepje van populaire meiden dat “The Plastics” wordt genoemd en dat wordt aangevoerd door queen bee Regina George en haar volgelingen Gretchen en Karen. Maar dan maakt Cady een grote fout en valt voor Regina’s ex-vriendje Aaron Samuels, waarna Regina zich tegen haar keert. Cady probeert het toproofdier van de groep ten val te brengen met hulp van haar vrienden, buitenbeentjes Janis en Damian. Daarbij moet ze proberen dicht bij zichzelf te blijven en zich staande te houden in de levensgevaarlijke jungle die de middelbare school is.
Nee, helaas is Mean Girls nog niet beschikbaar op Netflix in Nederland.
| Production | Lorne Michaels | Producer |
| Sound | Jeff Richmond | Original Music Composer |
| Writing | Nell Benjamin | Lyricist |
| Directing | Arturo Perez Jr. | Director |
| Directing | Samantha Jayne | Director |
| Production | Erin David | Producer |
| Production | Eric Gurian | Producer |
| Writing | Tina Fey | Musical |
| Crew | Kyle Hanagami | Choreographer |
| Camera | Bill Kirstein | Director of Photography |
| Production | Tina Fey | Producer |
| Production | Pamela Thur | Executive Producer |
| Crew | Jill Brown | Stunt Coordinator |
| Writing | Tina Fey | Screenplay |
| Production | Bernard Telsey | Casting |
| Production | Kristian Charbonier | Casting |
| Production | Tiffany Little Canfield | Casting |
| Art | Kelly McGehee | Production Design |
| Art | Jessica Petruccelli | Set Decoration |
| Costume & Make-Up | Tom Broecker | Costume Design |
| Writing | Nell Benjamin | Musical |
| Writing | Jeff Richmond | Musical |
| Directing | Jill Brown | Second Unit Director |
| Editing | Andrew Marcus | Editor |
| Costume & Make-Up | Patricia Ambroise | Makeup Artist |
| Costume & Make-Up | Dennis Bailey | Hair Department Head |
| Costume & Make-Up | Ashley DiSarro | Makeup Artist |
| Costume & Make-Up | Josh Marquette | Hair Designer |
| Costume & Make-Up | Milagros Medina-Cerdeira | Makeup Designer |
| Costume & Make-Up | Jenn 'Jorge' Nelson | Makeup Department Head |
| Costume & Make-Up | Bamike Ogunrinu | Makeup Artist |
| Costume & Make-Up | Mallory Pace | Hairstylist |
| Costume & Make-Up | Erica Pearce | Makeup Artist |
| Costume & Make-Up | Doria Riker | Makeup Artist |
| Costume & Make-Up | Aaron Worman | Makeup Artist |
| Costume & Make-Up | Shannon Thompson | Makeup Department Head |
| Art | Grant M Guilliams | Art Direction |
| Directing | Kyle Hanagami | Second Unit Director |
| Directing | Colin MacLellan | First Assistant Director |
| Directing | Lisa Simon | Second Assistant Director |
| Art | Cara Price | Assistant Art Director |
| Art | Caroline B. Scott | Set Decoration Buyer |
| Sound | Lewis Goldstein | Sound Re-Recording Mixer |
| Sound | Lewis Goldstein | Supervising Sound Editor |
| Sound | Bennett Kerr | Sound Effects Editor |
| Sound | Griffin Richardson | Sound Mixer |
| Sound | Brian Ronan | Sound Designer |
| Sound | Tom Ryan | Sound Re-Recording Mixer |
| Sound | Wen Hsuan Tseng | Foley Editor |
| Sound | Wen Hsuan Tseng | Foley Supervisor |
| Visual Effects | Ariel Altman | Visual Effects Supervisor |
| Visual Effects | Greg Babiuk | Visual Effects Producer |
| Visual Effects | Jeremy Beadell | Visual Effects Producer |
| Visual Effects | Gianny Carbone | VFX Artist |
| Visual Effects | Craig Crawford | Visual Effects Supervisor |
| Visual Effects | Thitaphon Piraban | VFX Artist |
| Crew | Joshua Planz | CG Supervisor |
| Visual Effects | Kim Rasser | Visual Effects Producer |
| Crew | Paige Rhea Allison | Stunt Double |
| Crew | Piper Brown | Stunts |
| Crew | Alesha Forche | Stunt Double |
| Crew | Justice Hedenberg | Stunts |
| Crew | Luke Lesko | Stunts |
| Crew | Alexa Marcigliano | Stunt Double |
| Crew | Emily Tung | Stunts |
| Camera | Anne Carson | Camera Operator |
| Lighting | Andy Day | Gaffer |
| Production | Keertana Sastry | Casting Associate |
| Sound | Megan Thee Stallion | Songs |
| Sound | Reneé Rapp | Songs |
| Writing | Rosalind Wiseman | Book |
| Production | Nell Benjamin | Executive Producer |
| Production | Jeff Richmond | Executive Producer |
| Production | Eric Gurian | Executive Producer |
| Production | Erin David | Executive Producer |
| Production | Caroline Maroney | Co-Producer |
| Production | Micah Frank | Co-Producer |
| Production | Guy Efrat | Unit Production Manager |
| Production | Pamela Thur | Unit Production Manager |
| Sound | Jack Grabow | Music Supervisor |
| Sound | Mary-Mitchell Campbell | Music Supervisor |
| Sound | Hanan Rubinstein | Music Producer |
| Camera | Stacy Mize | Additional Photography |
| Crew | Emely Cartagena | Stunts |
