Een minstreel droomt ervan een ongewerveld dier te worden en behandelt zichzelf met een elixer, dat hij heeft gewonnen uit enzymen van wormen. Helaas heeft het goedje een bijzonder onaangename nevenwerking, en tijdens de onvermijdelijke hallucinaties droomt de man van Shirley Temple in een Nazi-pakje, naakte mannen op gigantische schelpen en naakte vrouwen met apenmaskers.
Nee, helaas is What Is It? nog niet beschikbaar op Netflix in Nederland.
| Writing | Crispin Glover | Writer |
| Directing | Crispin Glover | Director |
| Production | Crispin Glover | Producer |
| Editing | Crispin Glover | Editor |
| Production | Matt Devlen | Producer |
| Production | John Grant | Executive Producer |
| Art | David Brothers | Set Designer |
| Sound | Molly Fitzjarrald | Assistant Sound Editor |
| Camera | Scott Henriksen | Additional Photography |
| Production | Cassian Elwes | Executive Producer |
| Production | Kim Davis-Wagner | Casting |
| Crew | Bruce Glover | Thanks |
| Crew | David Lynch | Thanks |
| Camera | Wyatt Troll | Director of Photography |
| Production | Michael Pallagi | Producer |
| Production | Ryan Page | Producer |
| Crew | Christopher McDaniel | Thanks |
| Camera | Billy Bob Williams | Additional Photography |
| Crew | Werner Herzog | Thanks |
| Crew | Tim Hunter | Thanks |
| Art | Cindy Epping | Set Decoration |
| Crew | Nicolas Cage | Thanks |
| Crew | Betty Glover | Thanks |
| Production | Mike Foley | Executive Producer |
| Camera | Crispin Glover | Additional Photography |
| Production | Phil Grossma | Executive Producer |
| Crew | Christopher Coppola | Thanks |
| Crew | Mark Mothersbaugh | Thanks |
| Sound | Crispin Glover | Music Supervisor |
| Art | Mike Hardy | Set Decoration |
| Camera | Scott Peterson | Additional Photography |
