Een minstreel droomt ervan een ongewerveld dier te worden en behandelt zichzelf met een elixer, dat hij heeft gewonnen uit enzymen van wormen. Helaas heeft het goedje een bijzonder onaangename nevenwerking, en tijdens de onvermijdelijke hallucinaties droomt de man van Shirley Temple in een Nazi-pakje, naakte mannen op gigantische schelpen en naakte vrouwen met apenmaskers.
Nee, helaas is What Is It? nog niet beschikbaar op Netflix in Nederland.
| Writing | Crispin Glover | Writer |
| Production | Crispin Glover | Producer |
| Directing | Crispin Glover | Director |
| Editing | Crispin Glover | Editor |
| Camera | Wyatt Troll | Director of Photography |
| Sound | Crispin Glover | Music Supervisor |
| Production | Cassian Elwes | Executive Producer |
| Production | Matt Devlen | Producer |
| Production | Mike Foley | Executive Producer |
| Production | Michael Pallagi | Producer |
| Production | John Grant | Executive Producer |
| Production | Phil Grossma | Executive Producer |
| Production | Ryan Page | Producer |
| Production | Kim Davis-Wagner | Casting |
| Art | David Brothers | Set Designer |
| Art | Cindy Epping | Set Decoration |
| Art | Mike Hardy | Set Decoration |
| Sound | Molly Fitzjarrald | Assistant Sound Editor |
| Camera | Crispin Glover | Additional Photography |
| Camera | Scott Henriksen | Additional Photography |
| Camera | Scott Peterson | Additional Photography |
| Camera | Billy Bob Williams | Additional Photography |
| Crew | David Lynch | Thanks |
| Crew | Mark Mothersbaugh | Thanks |
| Crew | Nicolas Cage | Thanks |
| Crew | Christopher Coppola | Thanks |
| Crew | Betty Glover | Thanks |
| Crew | Bruce Glover | Thanks |
| Crew | Werner Herzog | Thanks |
| Crew | Christopher McDaniel | Thanks |
| Crew | Tim Hunter | Thanks |
