Een agent afkomstig uit New York gaat samen met zijn vrouw op vakantie door Europa. Het doel hiervan is weer een vonk te laten ontstaan in het huwelijk. Echter gaat er al snel iets mis, want het koppel wordt op de hielen gezeten, omdat ze ergens van worden beschuldigd wat ze niet hebben gedaan.
Nee, helaas is Murder Mystery nog niet beschikbaar op Netflix in Nederland.
| Crew | Tony Sarandos | Post Production Assistant |
| Writing | James Vanderbilt | Screenplay |
| Directing | Kyle Newacheck | Director |
| Crew | Joe Watts | Stunts |
| Production | William Shively | Executive Producer |
| Crew | John Stoneham Jr. | Stunt Coordinator |
| Production | Beth Kono | Executive Producer |
| Directing | Gary Powell | Second Unit Director |
| Art | Michele Laliberte | Supervising Art Director |
| Production | Adam Sandler | Producer |
| Camera | Amir Mokri | Director of Photography |
| Production | James Vanderbilt | Producer |
| Production | Kathy Driscoll-Mohler | Casting |
| Production | Dan Bulla | Co-Producer |
| Art | Perry Andelin Blake | Production Design |
| Production | Lucas Smith | Executive Producer |
| Editing | Tom Costain | Editor |
| Production | Francine Maisler | Casting |
| Production | Joseph Vecsey | Co-Producer |
| Costume & Make-Up | Renée April | Costume Designer |
| Production | Allen Covert | Producer |
| Production | Russell Allen | Unit Production Manager |
| Production | Tripp Vinson | Producer |
| Production | Daniel Auclair | Unit Production Manager |
| Visual Effects | Christine Felman | Visual Effects Producer |
| Production | James D. Stern | Producer |
| Production | Barry Bernardi | Executive Producer |
| Production | Kevin Grady | Co-Producer |
| Directing | Jamie Christopher | First Assistant Director |
| Directing | Carole Dubuc | First Assistant Director |
| Production | A.J. Dix | Producer |
| Production | Tara Farney | Co-Producer |
| Editing | J.J. Titone | Additional Editor |
| Production | Julie Goldstein | Executive Producer |
| Production | Beau Flynn | Executive Producer |
| Production | Charlize Theron | Executive Producer |
| Production | Jennifer Aniston | Executive Producer |
| Crew | Emanuele Romano | Stunts |
| Crew | Martin Ivanov | Stunt Driver |
| Sound | Rupert Gregson-Williams | Original Music Composer |
| Camera | Igor Meglic | Second Unit Director of Photography |
