Earl Stone is een eenzame man op leeftijd en werkzaam als bloemist. Financieel gaat het hem niet voor de wind waardoor hij zich genoodzaakt ziet de boeken dicht te doen. Dan krijgt hij een voorstel om geld te verdienen als drugskoerier voor het Mexicaanse drugskartel.
Nee, helaas is The Mule nog niet beschikbaar op Netflix in Nederland.
| Directing | Clint Eastwood | Director |
| Production | Clint Eastwood | Producer |
| Writing | Nick Schenk | Screenplay |
| Production | Dan Friedkin | Producer |
| Editing | Joel Cox | Editor |
| Camera | Yves Bélanger | Director of Photography |
| Art | Kevin Ishioka | Production Design |
| Art | Rory Bruen | Art Direction |
| Art | Julien Pougnier | Art Direction |
| Costume & Make-Up | Deborah Hopper | Costume Design |
| Production | Jessica Meier | Producer |
| Production | Tim Moore | Producer |
| Production | Kristina Rivera | Producer |
| Production | Bradley Thomas | Producer |
| Sound | Goeun Lee | Sound Effects Editor |
| Sound | Darren Maynard | Sound Effects Editor |
| Sound | Alan Robert Murray | Supervising Sound Editor |
| Sound | John T. Reitz | Sound Re-Recording Mixer |
| Sound | John Joseph Thomas | Sound Effects Editor |
| Sound | Christian Wenger | Sound Effects Editor |
| Sound | Dean A. Zupancic | Sound Re-Recording Mixer |
| Production | Jillian Apfelbaum | Co-Producer |
| Production | David M. Bernstein | Co-Producer |
| Sound | Arturo Sandoval | Original Music Composer |
| Production | Geoffrey Miclat | Casting Director |
| Art | Ronald R. Reiss | Set Decoration |
| Sound | Steven Morrow | Sound Mixer |
| Production | Tara Feldstein Bennett | Casting |
| Production | Chase Paris | Casting |
| Art | Lindsay Good | Art Department Coordinator |
| Visual Effects | Terry Fitzpatrick | 24 Frame Playback |
| Camera | Eric Dvorsky | Aerial Camera Technician |
| Camera | Owen Patry | Aerial Camera |
| Camera | Hans Bjerno | Aerial Director of Photography |
| Lighting | David Elwell | Assistant Chief Lighting Technician |
| Camera | Michael Kellogg | Digital Imaging Technician |
| Lighting | James B. Crawford | Gaffer |
| Camera | James W. Apted | First Assistant "A" Camera |
| Camera | Matthew McGinn | First Assistant "B" Camera |
| Camera | Kyle Leftridge | Grip |
| Lighting | Tim Chang | Lighting Technician |
| Lighting | Brandon Crawford | Lighting Technician |
| Lighting | Tyler Childs | Rigging Gaffer |
| Lighting | Matt Shearer | Rigging Grip |
| Camera | Claire Folger | Still Photographer |
| Costume & Make-Up | Jack Taggart | Ager/Dyer |
| Costume & Make-Up | Michael Crow | Assistant Costume Designer |
| Costume & Make-Up | Mitchell Ray Kenney | Costume Supervisor |
| Costume & Make-Up | Dinah Lightsey | Costumer |
| Costume & Make-Up | Matthew Jerome | Set Costumer |
| Costume & Make-Up | Vicente Parada | Set Costumer |
| Costume & Make-Up | Kim Trujillo | Set Costumer |
| Costume & Make-Up | Kathy Oberlin | Tailor |
| Visual Effects | Amit Kumar | 2D Supervisor |
| Crew | Ryan Allen | Compositor |
| Crew | Abhishek Shaw | Compositor |
| Visual Effects | Richard Alonso | CG Artist |
| Visual Effects | Kelsey Elias | Digital Compositor |
| Visual Effects | Shizan Faisal | Digital Compositor |
| Visual Effects | Mrinal Ranjan | Digital Compositor |
| Crew | Jason Bowers | Digital Effects Supervisor |
| Crew | Liz Radley | CG Supervisor |
| Visual Effects | Graham Tailleur | Visual Effects Coordinator |
| Visual Effects | Adam Ohl | Visual Effects Producer |
| Visual Effects | Rick Sander | Visual Effects Supervisor |
| Directing | Ana Maria Quintana | Script Supervisor |
| Writing | Sam Dolnick | Original Concept |
| Crew | Thom Williams | Stunt Driver |
| Crew | Derek Russo | Stunts |
| Crew | Allen Robinson | Stunt Double |
| Crew | Charlie Parrish | Stunts |
| Crew | Aaron Matthews | Stunts |
| Crew | Warren Jones | Stunt Driver |
| Crew | Jenny Jerman | Stunt Driver |
| Crew | C.C. Ice | Stunts |
| Crew | Bobby Hernandez | Stunts |
| Crew | Alexander Hashioka Oatfield | Stunt Driver |
| Crew | Dean Grimes | Stunts |
| Crew | Scott Dale | Stunt Driver |
| Crew | Scott Dale | Utility Stunts |
| Crew | Eliza Coleman | Stunt Driver |
| Crew | Doug Coleman | Stunt Coordinator |
| Crew | Cristin Azure | Stunts |
| Crew | Trent Brya | Stunt Driver |
| Production | Todd Hoffman | Executive Producer |
| Production | Holly Hagy | Associate Producer |
| Production | Aaron L. Gilbert | Executive Producer |
| Production | Ruben Fleischer | Executive Producer |
| Production | David Bernad | Executive Producer |
