Op de trein van Parijs naar Venetië ontmoet Frank Tupelo, een leraar uit Wisconsin, de mooie en mysterieuze Elise Clifton-Ward. Elise is op weg naar Venetië voor een ontmoeting met haar man Alexander Pearce. Hij wordt gezocht door de Britse geheime dienst en een gangsterbaas. Elise heeft haar man al twee jaar niet meer gezien en na enkele chirurgische ingrepen weet eigenlijk niemand nog hoe hij er nu juist uitziet.
| Directing | Florian Henckel von Donnersmarck | Director |
| Sound | James Newton Howard | Original Music Composer |
| Writing | Florian Henckel von Donnersmarck | Screenplay |
| Writing | Julian Fellowes | Screenplay |
| Writing | Jérôme Salle | Original Story |
| Writing | Christopher McQuarrie | Screenplay |
| Costume & Make-Up | Colleen Atwood | Costume Design |
| Production | Gary Barber | Producer |
| Production | Roger Birnbaum | Producer |
| Production | Jonathan Glickman | Producer |
| Production | Tim Headington | Producer |
| Production | Graham King | Producer |
| Production | Susie Figgis | Casting |
| Camera | John Seale | Director of Photography |
| Editing | Joe Hutshing | Editor |
| Editing | Patricia Rommel | Editor |
| Art | Jon Hutman | Production Design |
| Art | Susanna Codognato | Art Direction |
| Art | Anna Pinnock | Set Decoration |
| Costume & Make-Up | Suzi Turnbull | Costume Supervisor |
| Art | Marco Trentini | Supervising Art Director |
| Production | Denis O'Sullivan | Co-Producer |
| Production | Adam Rosenberg | Producer |
| Production | Olivier Courson | Executive Producer |
| Production | Ron Halpern | Executive Producer |
| Production | John Bernard | Line Producer |
| Production | Jeffrey Nachmanoff | Co-Producer |
| Production | David Nichols | Line Producer |
| Production | Bahman Naraghi | Executive Producer |
| Production | Lloyd Phillips | Executive Producer |
| Costume & Make-Up | Giorgio Gregorini | Hair Designer |
| Costume & Make-Up | Peter Nicastro | Hairstylist |
| Costume & Make-Up | Veronica McAleer | Hairstylist |
| Costume & Make-Up | Karen Asano-Myers | Hairstylist |
| Costume & Make-Up | Colin Jamison | Hairstylist |
| Costume & Make-Up | Fulvio Pozzobon | Key Hair Stylist |
| Costume & Make-Up | Frédérique Arguello | Key Hair Stylist |
| Costume & Make-Up | Maurizio Silvi | Key Makeup Artist |
| Costume & Make-Up | Françoise Quilichini | Key Makeup Artist |
| Costume & Make-Up | Novella Borghi | Makeup Artist |
| Costume & Make-Up | Joel Harlow | Makeup Artist |
| Costume & Make-Up | Toni G | Makeup Artist |
| Art | Silvia Di Lena | Art Department Coordinator |
| Art | Olivier Crespin | Property Master |
| Art | Antonio Fraulo | Property Master |
| Art | Antonio Tarolla | Set Designer |
| Art | Anita Tomaselli | Art Department Coordinator |
| Art | Bradley Torbett | Property Master |
| Camera | Glyn Williams | Aerial Camera Technician |
| Camera | John Marzano | Aerial Director of Photography |
| Camera | Emiliano Leurini | Camera Operator |
| Camera | Marco Sacerdoti | Camera Operator |
| Camera | Daniele Massaccesi | Steadicam Operator |
| Lighting | Elvis Pasqual | Gaffer |
| Camera | Claudio Del Gobbo | Dolly Grip |
| Camera | Stefano Di Pasquali | Dolly Grip |
| Lighting | Stefano Marino | Gaffer |
| Lighting | Jean-François Drigeard | Gaffer |
| Lighting | Morris Flam | Gaffer |
| Camera | Tommaso Mele | Key Grip |
| Camera | Cyril Kuhnholtz | Key Grip |
| Lighting | Marco Sticchi | Rigging Gaffer |
| Lighting | Werner Bacciu | Rigging Grip |
| Lighting | Tommaso Baratto | Rigging Grip |
| Lighting | Regis Benedettelli | Rigging Grip |
| Lighting | Paolo Forti | Rigging Grip |
| Lighting | Antonio Viola | Rigging Grip |
| Lighting | Nicola Zangrando | Rigging Grip |
| Costume & Make-Up | Christine L. Cantella | Assistant Costume Designer |
| Costume & Make-Up | Laurence Caines | Costume Supervisor |
| Costume & Make-Up | Catherine Buyse Dian | Wardrobe Supervisor |
| Costume & Make-Up | Bruno de Santa | Set Costumer |
| Editing | Nick Monton | Digital Intermediate |
| Editing | David Bilow | First Assistant Editor |
| Art | Ahmet Ahmet | Title Designer |
| Directing | Dianne Dreyer | Script Supervisor |
| Crew | Joss Skottowe | Armorer |
| Crew | Luca Tommassini | Choreographer |
| Crew | Marc Wolff | Aerial Coordinator |
| Crew | Marc Wolff | Pilot |
| Crew | Massimo Cardajoli | Armorer |
| Sound | Kirsty Whalley | Music Editor |
| Sound | Joe E. Rand | Music Editor |
| Crew | Ken Locsmandi | Digital Effects Supervisor |
| Crew | John Swinnerton | Digital Effects Supervisor |
| Crew | Laura Fitzpatrick | Digital Effects Producer |
| Visual Effects | Zack Fox | Visual Effects Coordinator |
| Visual Effects | Tamar Shaham | Visual Effects Coordinator |
| Crew | David Matusek | Visual Effects Editor |
| Visual Effects | David Sanger | Visual Effects Producer |
| Visual Effects | Thomas F. Ford IV | Visual Effects Producer |
| Visual Effects | Matthew Gratzner | Visual Effects Supervisor |
| Visual Effects | Ted Rae | Visual Effects Supervisor |
| Visual Effects | Dominic Tuohy | Special Effects Supervisor |
| Sound | Michael Hertlein | ADR Editor |
| Sound | Margit Pfeiffer | ADR Editor |
| Sound | Tom Hartig | Boom Operator |
| Sound | Michael Hertlein | Dialogue Editor |
| Sound | Margit Pfeiffer | Dialogue Editor |
| Sound | Katherine Rose | Foley |
| Sound | Dror Mohar | Foley Editor |
| Sound | Craig S. Jaeger | Foley Editor |
| Sound | Ann Scibelli | Sound Effects Designer |
| Sound | Charlie Campagna | Sound Effects Editor |
| Sound | Harry Cohen | Sound Effects Editor |
| Sound | Hector C. Gika | Sound Effects Editor |
| Sound | Scott Millan | Sound Re-Recording Mixer |
| Sound | David Parker | Sound Re-Recording Mixer |
| Sound | Wylie Stateman | Supervising Sound Editor |
| Sound | Renée Tondelli | Supervising Sound Editor |
| Production | Barbara Harris | ADR Voice Casting |
| Production | Stéphane Foenkinos | Casting |
| Production | Béatrice Kruger | Casting |
