Een reusachtige buitenaardse spin ontsnapt uit een militair laboratorium en terroriseert Los Angeles. Het leger probeert de spin uit te schakelen door middel van een militaire aanval, maar faalt daarin. Het is aan een groep wetenschappers en een slimme verdelger de spin definitief uit te schakelen, voordat het te laat is voor de stad.
Nee, helaas is Big Ass Spider! nog niet beschikbaar op Netflix in Nederland.
| Art | Cleve Hall | Prop Designer |
| Writing | Gregory Gieras | Writer |
| Directing | Mike Mendez | Director |
| Camera | Benji Bakshi | Director of Photography |
| Crew | Gavin Keathley | Thanks |
| Sound | Jake Render | Orchestrator |
| Crew | Mark Riccardi | Stunt Double |
| Costume & Make-Up | Rianna Crittendon | Hairstylist |
| Camera | Benjamin Semanoff | "B" Camera Operator |
| Directing | Lauren Elizabeth Hood | Second Assistant Director |
| Camera | Drew Adams | Additional Photography |
| Crew | Tony Snegoff | Stunts |
| Costume & Make-Up | Roy Knyrim | Makeup Effects Designer |
| Production | Shaked Berenson | Producer |
| Camera | Benjamin Semanoff | Camera Operator |
| Crew | Robin Petgrave | Pilot |
| Costume & Make-Up | Emma Jacobs | Makeup Department Head |
| Sound | Sean Fernald | Music Supervisor |
| Camera | Lamar Sulaka | Camera Operator |
| Production | Patrick Ewald | Producer |
| Sound | Sean Gray | Sound Designer |
| Costume & Make-Up | Emma Jacobs | Hair Department Head |
| Sound | David Kitchens | Sound Designer |
| Sound | Kenneth Skoglund | Sound Effects Editor |
| Directing | Erin Grumley | Script Supervisor |
| Editing | Mike Mendez | Editor |
| Lighting | Justen Hernandez | Gaffer |
| Editing | Vanessa Ruane | Assistant Editor |
| Visual Effects | Mohammad Bilal | Visual Effects Supervisor |
| Sound | Gonzalo 'Bino' Espinoza | ADR Supervisor |
| Camera | Shaun Giordano | Key Grip |
| Directing | Sara Branscum | Script Supervisor |
| Production | Erik Olson | Line Producer |
| Production | Klaus von Sayn-Wittgenstein | Producer |
| Sound | Bull Sanchez | Boom Operator |
| Production | Travis Stevens | Producer |
| Visual Effects | Asif Iqbal | Visual Effects Producer |
| Crew | Bobby C. King | Stunt Coordinator |
| Art | Sxv'leithan Essex | Production Design |
| Directing | Joshua Lou Friedman | First Assistant Director |
| Lighting | Joseph B. Hernandez | Best Boy Electric |
| Lighting | Daryl Norrbom | Best Boy Electric |
| Camera | Ari Robbins | Steadicam Operator |
| Costume & Make-Up | Ambre Wrigley | Costume Design |
| Sound | Ceiri Torjussen | Original Music Composer |
