De student Eddie Kasalivich werk als technicus voor een wetenschappelijk team dat een alternatieve energiebron ontdekt. Wanneer één van de wetenschappers vermoord en de uitvinding gestolen wordt, krijgen Eddie en natuurkundige Lily Sinclair hier de schuld van. Ze moeten vluchten voor hun leven, met de FBI, CIA en andere partijen achter zich aan. Paul Shannon, Eddie's mentor, is de baas van een wetenschappelijk bedrijf dat commerciële interesse heeft in de uitvinding.
Nee, helaas is Chain Reaction nog niet beschikbaar op Netflix in Nederland.
| Directing | Andrew Davis | Director |
| Writing | J.F. Lawton | Screenplay |
| Writing | Michael Bortman | Screenplay |
| Camera | Frank Tidy | Director of Photography |
| Editing | Arthur Schmidt | Editor |
| Editing | Don Brochu | Editor |
| Editing | Dov Hoenig | Editor |
| Production | Andrew Davis | Producer |
| Production | Arne Schmidt | Producer |
| Production | Richard D. Zanuck | Executive Producer |
| Editing | Mark Stevens | Editor |
| Art | David J. Bomba | Art Direction |
| Art | Maher Ahmad | Production Design |
| Art | Gene Serdena | Set Decoration |
| Production | Maher Ahmad | Associate Producer |
| Production | Carlos H. Sánchez | Associate Producer |
| Production | Teresa Tucker-Davies | Associate Producer |
| Costume & Make-Up | Jodie Lynn Tillen | Costume Design |
| Sound | Jerry Goldsmith | Original Music Composer |
| Production | Erwin Stoff | Executive Producer |
| Art | Dana Armonda | Art Department Coordinator |
| Art | Ann Harris | Assistant Art Director |
| Art | Bruce J. Gfeller | Construction Coordinator |
| Art | Carlos Medina Jr. | Greensman |
| Art | Joel Prihoda | Leadman |
| Art | Kathleen Beall | Location Scout |
| Art | James Cimbalista | Painter |
| Art | Richard Fernandez | Set Designer |
| Art | John Mikels | Standby Painter |
| Camera | George Kohut | Camera Operator |
| Camera | Bob Rose | Key Grip |
| Camera | Dennis De La Mata | Grip |
| Camera | Frank M. Holgate | Aerial Director of Photography |
| Camera | Murray Close | Still Photographer |
| Costume & Make-Up | Alexandria Forster | Costume Supervisor |
| Costume & Make-Up | Deena Adair | Hairstylist |
| Costume & Make-Up | Fríða Aradóttir | Key Hair Stylist |
| Costume & Make-Up | Michael Hancock | Makeup Artist |
| Costume & Make-Up | Jacqueline S. Beatka | Seamstress |
| Costume & Make-Up | Patrick Caulfield | Set Costumer |
| Costume & Make-Up | Tighe Barry | Set Dressing Artist |
| Crew | Frank Battaglia | Carpenter |
| Crew | Ken Cabrera | Craft Service |
| Crew | David Isyomin | Digital Effects Supervisor |
| Crew | Connie Kallos | Makeup Effects |
| Crew | Justine A. Bello | Post Production Assistant |
| Crew | Lowell D. Blank | Post Production Supervisor |
| Crew | Kieran Woo | Production Controller |
| Crew | Jeff Manimbo | Production Intern |
| Crew | D.B. Griffith | Projection |
| Crew | John J. Slove Jr. | Propmaker |
| Art | Kirk Corwin | Property Master |
| Crew | Janet L. Contursi | Set Medic |
| Sound | Gregory Cheever | Sound Recordist |
| Crew | Roy Arbogast | Special Effects Coordinator |
| Crew | Walter Scott | Stunt Coordinator |
| Crew | Joni Avery | Stunts |
| Crew | William T. Hogan III | Transportation Captain |
| Crew | Michael P. Deal | Transportation Co-Captain |
| Crew | George DiLeonardi | Transportation Coordinator |
| Production | Stephen Lim | Unit Production Manager |
| Crew | Deborah Simmrin | Unit Publicist |
| Crew | Kent Shelton | Utility Stunts |
| Crew | Daniel H. Friedman | Video Assist Operator |
| Crew | Tommy Dorsett | Visual Effects Editor |
| Directing | Matt Earl Beesley | First Assistant Director |
| Editing | Bob Putynkowski | Color Timer |
| Sound | David A. Arnold | Dialogue Editor |
| Editing | Renée Bergan | Editorial Production Assistant |
| Editing | R. Orlando Duenas | First Assistant Editor |
| Lighting | Anthony J. Lullo | Best Boy Electric |
| Lighting | Lawrence J. Anderson Jr. | Electrician |
| Lighting | Alphonse Blumenthal | Gaffer |
| Lighting | John P. Friday | Rigging Gaffer |
| Lighting | Scott Baehrend | Rigging Grip |
| Production | Erica Arvold | Casting Associate |
| Production | K. Lenna Katich | Production Accountant |
| Production | Lisa A. Becker | Production Coordinator |
| Sound | R.J. Kizer | ADR Supervisor |
| Sound | Kenneth C. Mantlo | Boom Operator |
| Sound | Paul Apted | Assistant Sound Editor |
| Sound | Kenneth Hall | Music Editor |
| Sound | Arthur Morton | Orchestrator |
| Sound | Randy Thom | Sound Designer |
| Sound | Craig Berkey | Sound Effects Editor |
| Sound | Robert J. Anderson Jr. | Sound Mixer |
| Sound | David E. Stone | Supervising Sound Editor |
| Visual Effects | Dennis Davis | Digital Compositors |
| Visual Effects | James Reedy | Special Effects Supervisor |
| Visual Effects | David Sanger | Visual Effects Coordinator |
| Visual Effects | Thom Randmaa | Visual Effects Producer |
| Visual Effects | Nick Davis | Visual Effects Supervisor |
| Camera | John S. Robertson | Key Grip |
| Writing | Arne Schmidt | Story |
| Writing | Rick Seaman | Story |
| Writing | Josh Friedman | Story |
| Costume & Make-Up | Jane Blank | Costumer |
| Costume & Make-Up | Gina Panno | Key Set Costumer |
| Directing | Ken Paull | Second Assistant Director |
| Directing | James A. Dennett II | Second Second Assistant Director |
| Art | Troy Borisy | Assistant Property Master |
| Art | Matt Codd | Conceptual Illustrator |
| Art | Timothy Burgard | Storyboard Artist |
| Sound | Cliff Latimer | ADR Editor |
| Sound | Chuck Rapp | ADR Mixer |
| Sound | Ric Coken | ADR Recordist |
| Sound | Sonny Pettijohn | First Assistant Sound Editor |
| Sound | Vanessa Theme Ament | Foley Artist |
| Sound | Karin Roulo | Foley Mixer |
| Sound | Sandy Garcia | Foley Recordist |
| Sound | John A. Larsen | Sound Supervisor |
| Crew | Michael Ahasay | Special Effects Technician |
| Visual Effects | Andre Bustanoby | VFX Artist |
| Visual Effects | Russell j Lyster | VFX Director of Photography |
| Visual Effects | Andrew Garcia-Price | Visual Effects Production Assistant |
| Crew | William Morts | Stunt Double |
| Camera | Erich O. Rose | Best Boy Grip |
| Camera | Steven Silverstein | Camera Loader |
| Camera | Fernando M. Briones | Dolly Grip |
| Camera | Gregg Gannett | Second Assistant Camera |
| Production | Terri Douglas | ADR Voice Casting |
| Editing | Erin Michelle Hopkins | Assistant Editor |
| Editing | Jeffrey Kalmus | Color Grading |
| Editing | Donah Bassett | Negative Cutter |
| Production | Jean Nakahara | Post Production Coordinator |
| Production | Laurence Byrne | Assistant Location Manager |
| Production | Brady Breen | Location Assistant |
| Production | Marcie Friedman | Location Coordinator |
| Sound | Jerry Goldsmith | Conductor |
| Production | Anthony Medina | Art Department Production Assistant |
| Production | Malisa Caroselli | Assistant Accountant |
| Crew | Karin Anderson | Assistant Craft Service |
| Production | B. Ted Deiker | Assistant Production Coordinator |
| Production | Joan Philo | Extras Casting |
| Production | Sarayu Blue | Extras Casting Assistant |
| Production | Suzanne De Grandis | First Assistant Accountant |
| Lighting | Morgan Michael Lewis | Key Rigging Grip |
| Production | Michael Salven | Key Set Production Assistant |
| Crew | Don Riozz McNichols | Key Special Effects |
| Production | Patricia S. Kingery | Payroll Accountant |
| Crew | Cliff Fleming | Pilot |
| Production | Don H. Julien | Production Assistant |
| Crew | Joseph M. Brennan | Technical Advisor |
| Directing | Matt Earl Beesley | Second Unit Director |
| Camera | Donald Carlson | First Assistant Camera |
| Crew | Linda Perlin | Stunts |
| Crew | Marian Green | Stunts |
