Het honkbalteam The Cleveland Indians heeft in 34 jaar geen succes behaald. Voormalig nachtclubdanseres Rachel Phelps trouwt de eigenaar van het team. Hij overleeft de huwelijksreis niet, en zij erft het team van hem. Zij haat Cleveland, en wil graag een nieuw stadion betrekken in een warmer klimaat, zoals Miami, Florida. De enige manier waarop zij onder het contract met Cleveland uit kan komen, is wanneer het bezoekersaantal onder de 800.000 komt. Om dat te bereiken stelt ze het slechts denkbare team samen. Wanneer het team er achter komt wat de bedoeling van Rachel Phelps is, besluiten ze terug te vechten.
Nee, helaas is Major League nog niet beschikbaar op Netflix in Nederland.
| Camera | Reynaldo Villalobos | Director of Photography |
| Directing | David S. Ward | Director |
| Production | Joanne Zaluski | Casting |
| Production | Irby Smith | Producer |
| Production | Chris Chesser | Producer |
| Production | Mark Rosenberg | Executive Producer |
| Art | Jeffrey Howard | Production Design |
| Production | Julie Bergman Sender | Co-Producer |
| Costume & Make-Up | Erica Edell Phillips | Costume Design |
| Sound | James Newton Howard | Original Music Composer |
| Crew | G.A. Aguilar | Stunts |
| Crew | Rick LeFevour | Stunt Coordinator |
| Costume & Make-Up | Patti Cameron | Wardrobe Assistant |
| Directing | Christine Larson | Second Assistant Director |
| Costume & Make-Up | John Wabisca | Makeup Artist |
| Production | Edward D. Markley | Unit Production Manager |
| Art | John Krenz Reinhart Jr. | Art Direction |
| Costume & Make-Up | Michael Becker | Costume Supervisor |
| Costume & Make-Up | Peggy Teague | Makeup & Hair Assistant |
| Costume & Make-Up | Sherrie Brody | Wardrobe Assistant |
| Art | Celeste Lee | Set Decoration |
| Directing | Irby Smith | Second Unit Director |
| Art | Bill Rea | Set Designer |
| Directing | Richard Patrick | Second Assistant Director |
| Art | Patrick Cassidy | Assistant Set Decoration |
| Sound | Laura Derrick | Boom Operator |
| Costume & Make-Up | Frances Mathias | Hairstylist |
| Sound | Susumu Tokunow | Sound Mixer |
| Editing | Dennis M. Hill | Editor |
| Crew | Michael F. Twarog | Stunts |
| Production | Irby Smith | Unit Production Manager |
| Directing | Louis D'Esposito | First Assistant Director |
| Camera | James Pergola | Second Unit Director of Photography |
| Crew | Alex Flores | Stunts |
| Crew | Stacy Logan | Stunts |
| Crew | Ted White | Stunts |
| Editing | Tony Lombardo | Editor |
| Crew | Dieter Sturm | Special Effects |
| Costume & Make-Up | Laurie Hudson | Wardrobe Supervisor |
| Directing | Jerry Grandey | First Assistant Director |
| Costume & Make-Up | Judith Denny | Makeup & Hair Assistant |
| Sound | Randy Newman | Songs |
| Writing | David S. Ward | Writer |
