Nadat Alison Jones door een stom toeval hoort, dat haar aanstaande Sam met zijn ex-vrouw naar bed is geweest, wijst ze hem direct het gat van de deur. Dat betekent wel, dat ze vanaf dat moment alleen in een groot appartement in een nogal sinistere buurt. Allie besluit een advertentie te plaatsen voor een kamergenote. Hedra Carlson is een geschenk uit de hemel. Het ingetogen meisje is dankbaar voor de kamer die ze met Allie mag delen. Wel eist Hedy dat Sam in geen geval meer terug komt om haar plaats weer in te nemen, maar Allie stelt haar gerust. Meer en meer trekken de meisjes met elkaar op, totdat Allie onaangenaam verrast wordt door Hedy, die zich langzamerhand alle uiterlijke kenmerken van haar kamergenote gaat aanmeten. Dan komt Sam plotseling weer opdagen en dat bevalt Hedy niet. Voor Allie's ogen voltrekt zich een beangstigende verandering. De perfecte kamergenote wordt de huiveringwekkendste nachtmerrie.
Nee, helaas is Single White Female nog niet beschikbaar op Netflix in Nederland.
| Directing | Barbet Schroeder | Director |
| Writing | John Lutz | Novel |
| Writing | Don Roos | Screenplay |
| Production | Barbet Schroeder | Producer |
| Sound | Howard Shore | Original Music Composer |
| Production | Jack Baran | Executive Producer |
| Camera | Luciano Tovoli | Director of Photography |
| Editing | Lee Percy | Editor |
| Crew | Joni Avery | Stunts |
| Crew | Jamie Jo Medearis | Stunts |
| Production | Roger Joseph Pugliese | Unit Production Manager |
| Directing | Daniel R. Suhart | Second Assistant Director |
| Art | James F. Truesdale | Assistant Art Director |
| Editing | Emily Wallin | Assistant Editor |
| Editing | Sarah Peddie | Assistant Editor |
| Directing | Wilma Garscadden-Gahret | Script Supervisor |
| Camera | Monty Rowan | Camera Operator |
| Camera | Bob Hall | First Assistant Camera |
| Camera | Brian LeGrady | Second Assistant Camera |
| Costume & Make-Up | Elisabetta Beraldo | Assistant Costume Designer |
| Costume & Make-Up | Eileen Kennedy | Costume Supervisor |
| Costume & Make-Up | Jaqueline De La Fontaine | Costumer |
| Lighting | Mike Moyer | Chief Lighting Technician |
| Lighting | David Burnett | Assistant Chief Lighting Technician |
| Camera | Gary Dagg | Key Grip |
| Camera | Joe Kelly | Best Boy Grip |
| Camera | David Nims | Dolly Grip |
| Crew | Edward J. Ulrich | Stunt Coordinator |
| Crew | Eddie Surkin | Special Effects |
| Production | Elyse Katz | Production Coordinator |
| Production | Margaret Mitchell | Production Accountant |
| Production | Jakki Fink | Casting Assistant |
| Art | Walt Hadfield | Construction Coordinator |
| Art | James F. Walker | Construction Foreman |
| Art | Douglas E. Maxwell | Leadman |
| Crew | Tom Briggs | Transportation Coordinator |
| Sound | Tim Holland | Supervising Sound Editor |
| Sound | Gloria S. Borders | Supervising Sound Editor |
| Sound | Don Hall | Sound Editor |
| Sound | Ken Fischer | Sound Editor |
| Sound | Ethan Van der Ryn | Sound Editor |
| Sound | Robert Shoup | Sound Editor |
| Sound | Marilyn McCoppen | Sound Editor |
| Sound | Gwendolyn Yates Whittle | Sound Editor |
| Sound | E. Jeane Putnam | Sound Editor |
| Sound | Claire Sanfilippo | Assistant Sound Editor |
| Sound | J.R. Grubbs | Assistant Sound Editor |
| Sound | Jim Weidman | Music Editor |
| Sound | Gary Rydstrom | Sound Designer |
| Sound | Christopher Boyes | Assistant Sound Designer |
| Sound | Tom Myers | Assistant Sound Designer |
| Sound | Carl Fischer | Boom Operator |
| Sound | Tom Johnson | Sound Re-Recording Mixer |
| Sound | Gary Rydstrom | Sound Re-Recording Mixer |
| Sound | Richard Beggs | Sound Re-Recording Mixer |
| Camera | François Duhamel | Still Photographer |
| Crew | Beverly Walker | Unit Publicist |
| Art | Robert Dawson | Title Designer |
| Crew | James Brown | Transportation Captain |
| Production | Susan Hoffman | Associate Producer |
| Production | Roger Joseph Pugliese | Co-Producer |
| Production | Howard Feuer | Casting |
| Art | Milena Canonero | Production Design |
| Art | P. Michael Johnston | Art Direction |
| Art | Anne H. Ahrens | Set Decoration |
| Costume & Make-Up | Milena Canonero | Costume Design |
| Costume & Make-Up | Lizbeth Williamson | Makeup Artist |
| Costume & Make-Up | Candace Neal | Hairstylist |
| Costume & Make-Up | Matthew W. Mungle | Special Effects Makeup Artist |
