Julianne (Julia Roberts) en Michael hebben de afspraak dat, als ze beiden nog vrijgezel zijn vóór hun 28ste verjaardag, zij met elkaar zullen trouwen. Maar vier dagen voor de kritieke ‘deadline’ belt Michael Julianne op met de heugelijke mededeling dat hij de ware heeft gevonden. Jullianne is vast van plan om Michael's voorgenomen huwelijk met de vrouw van zijn dromen, de piepjonge Kimmy (Cameron Diaz), te saboteren en ze gaat hen opzoeken. Helaas blijkt de ‘aanstaande’ van Michael een schat van een meid te zijn. Maar, schattig of niet, voor Julianne dringt de tijd. Over drie dagen is de bruiloft en die zal, wat haar betreft, zeker geen doorgang vinden!
Nee, helaas is My Best Friend's Wedding nog niet beschikbaar op Netflix in Nederland.
| Editing | Garth Craven | Editor |
| Production | Jerry Zucker | Producer |
| Camera | László Kovács | Director of Photography |
| Sound | James Newton Howard | Original Music Composer |
| Production | Gil Netter | Executive Producer |
| Directing | P.J. Hogan | Director |
| Production | Ronald Bass | Producer |
| Writing | Ronald Bass | Screenplay |
| Production | Patricia Whitcher | Executive Producer |
| Editing | Lisa Fruchtman | Editor |
| Crew | Rick LeFevour | Stunt Coordinator |
| Crew | Linda Perlin | Stunts |
| Crew | Stacy Logan | Stunts |
| Production | David Rubin | Casting |
| Costume & Make-Up | Jeffrey Kurland | Costume Design |
| Art | Karen Fletcher Trujillo | Art Direction |
| Art | Richard Sylbert | Production Design |
| Sound | John Morris | Supervising Sound Editor |
| Art | William Kemper Wright | Set Decoration |
| Crew | Carl Paoli | Stunt Double |
| Directing | Eric Heffron | First Assistant Director |
| Directing | Richard Oswald | Second Assistant Director |
| Costume & Make-Up | Richard Dean | Makeup Designer |
| Costume & Make-Up | Noriko Watanabe | Makeup Department Head |
| Crew | Mark Harper | Stunts |
| Costume & Make-Up | Deborah K. Dee | Key Hair Stylist |
| Costume & Make-Up | Karen Lynn Accattato | Makeup Artist |
| Crew | Tom Ryba | Special Effects Coordinator |
| Camera | George Kohut | "A" Camera Operator |
| Lighting | Richmond L. Aguilar | Chief Lighting Technician |
| Crew | James Fierro | Stunts |
| Production | Bill Johnson | Associate Producer |
| Crew | Eddie J. Fernandez | Stunts |
| Crew | Kay Whipple | Stunts |
| Camera | Suzanne Tenner | Still Photographer |
| Directing | Dru Anne Carlson | Script Supervisor |
| Directing | Richard S. Lederer | Second Second Assistant Director |
| Crew | Daniel Maldonado | Stunts |
| Crew | Toni Basil | Choreographer |
| Art | Wenden K. Baldwin | Title Designer |
| Costume & Make-Up | Lyndell Quiyou | Hair Designer |
| Costume & Make-Up | Anne Morgan | Hair Department Head |
| Production | Patricia Whitcher | Unit Production Manager |
| Sound | Bonnie Greenberg | Music Supervisor |
| Costume & Make-Up | Linda Melazzo | Key Makeup Artist |
| Crew | Brian Christensen | Stunts |
| Camera | Gerrit Dangremond | "B" Camera Operator |
| Crew | Tom Lowell | Stunts |
| Costume & Make-Up | John Glaser | Assistant Costume Designer |
| Production | Ray Conchado | Production Assistant |
