Tijdens een reis voor hun werk, belanden een schrijver en een accountant in bed. Zij is weliswaar getrouwd en hij heeft ook een andere relatie, maar de aantrekkingskracht tussen de twee zorgt dat de one-night-stand uitgroeit tot een meer intense relatie die een vlucht uit de routine van alledag wordt. Door een aaneenschakeling van gebeurtenissen ontwikkelt de relatie zich tot één die de belangrijkste in hun leven zal worden.
Nee, helaas is 28 Hotel Rooms nog niet beschikbaar op Netflix in Nederland.
| Directing | Matt Ross | Director |
| Writing | Matt Ross | Writer |
| Costume & Make-Up | Jamie Redwood | Costume Design |
| Directing | Jason Mesias | Second Assistant Director |
| Art | Jenna Craig | Set Dresser |
| Production | Chris Messina | Executive Producer |
| Directing | Keith Allen Cox | Second Assistant Director |
| Sound | Akash Singh | Boom Operator |
| Camera | Joseph Joyce | Second Assistant Camera |
| Camera | Buddy Allen Thomas | First Assistant "A" Camera |
| Costume & Make-Up | Lauren Fajardo | Wardrobe Supervisor |
| Sound | Trevor Gates | Foley Mixer |
| Sound | Ginger Geary | Foley Artist |
| Sound | Fred Stuben | Sound Mixer |
| Sound | Jay Verkamp | Sound Mixer |
| Camera | Learan Kahanov | Camera Operator |
| Camera | Clair Popkin | First Assistant Camera |
| Camera | Augusta Quirk | Still Photographer |
| Editing | Cassidy Greenwood | Digital Intermediate Colorist |
| Directing | Liz Edwards | Script Supervisor |
| Costume & Make-Up | Julia Caston | Costume Design |
| Directing | Rashi DeStefano | Second Assistant Director |
| Sound | Steven Iba | Supervising Sound Editor |
| Sound | Spencer Schwieterman | Assistant Sound Editor |
| Camera | Lacey Terrell | Still Photographer |
| Camera | Timothy Trotman | First Assistant "A" Camera |
| Editing | Evan Schrodek | Assistant Editor |
| Production | Ari Finklestein | Production Assistant |
| Production | Stefan Nowicki | Executive Producer |
| Sound | Chris Terhune | ADR Mixer |
| Sound | Scott Brewster | Dialogue Editor |
| Camera | Justin Fidencio Reyes | Grip |
| Editing | Gemma Townsend | Digital Intermediate Colorist |
| Production | Ross Louis Klein | Production Assistant |
| Production | Joey Carey | Executive Producer |
| Production | Louise Runge | Producer |
| Costume & Make-Up | Jacqueline Pietro | Hairstylist |
| Sound | Matt Culbreath | Assistant Sound Editor |
| Camera | Doug Emmett | Director of Photography |
| Sound | Trevor Gates | Sound Editor |
| Sound | Richard Kitting | Sound Re-Recording Mixer |
| Camera | Jay Todd | Key Grip |
| Production | T.J. Ayer | Production Assistant |
| Production | Olivia Bosek | Assistant Production Coordinator |
| Production | Chris Terwilliger | Production Assistant |
| Editing | Joseph Krings | Editor |
| Camera | Christopher Rash | Additional Grip |
| Camera | Josh Smith | Grip |
| Production | Andrew M. Kennedy | Production Assistant |
| Directing | Evan Kenward | Script Supervisor |
| Costume & Make-Up | Yvonne Wang | Key Hair Stylist |
| Sound | Fred Stuben | Boom Operator |
| Sound | Will Bates | Original Music Composer |
| Costume & Make-Up | Yvonne Wang | Key Makeup Artist |
| Sound | Kelly Vockel | Assistant Dialogue Editor |
| Camera | Joshua Bushek | Best Boy Grip |
| Camera | Brian Patrick Carroll | First Assistant Camera |
| Camera | Wyatt Harte | Additional Grip |
| Camera | Thomas Holzer | Additional First Assistant Camera |
| Camera | Maximo L. Verdes II | Grip |
| Production | Alex Sagalchik | Executive Producer |
| Sound | Lucy Alper | Music Coordinator |
| Costume & Make-Up | Lauren Ernsdorf | Additional Hairstylist |
| Directing | Scott Larkin | First Assistant Director |
| Sound | Akash Singh | Sound Mixer |
| Production | Andrew Meieran | Executive Producer |
| Costume & Make-Up | Linda Kaufman | Key Hair Stylist |
| Production | Samantha Housman | Producer |
| Production | Crystal Powell | Co-Producer |
| Production | Samantha Housman | Unit Production Manager |
| Directing | Benjamin Wilkins | First Assistant Director |
| Sound | Scott Brewster | ADR Editor |
| Sound | Chris Terhune | Sound Effects Editor |
| Production | Jessica Engel | Producer's Assistant |
| Production | Blythe Wolber | Production Assistant |
| Camera | Gregory Giamportane | Grip |
| Camera | Justin Hutchinson | Grip |
| Camera | Jordan Bell | Key Grip |
| Editing | Jon Pehlke | Digital Intermediate Editor |
| Production | Lynette Howell Taylor | Producer |
| Costume & Make-Up | Steve Costanza | Additional Hairstylist |
| Directing | Mitch Yapko | First Assistant Director |
| Sound | Joshua Adeniji | Foley Editor |
| Production | Blair Richman | Producer's Assistant |
| Crew | Nicola B. Marsh | Thanks |
| Sound | Jay Verkamp | Boom Operator |
| Production | Sarah Herbst | Production Assistant |
| Camera | Nicholas Allen | Additional First Assistant Camera |
| Lighting | T.J. Alston | Gaffer |
| Camera | Johanna Ansnick | Additional Second Assistant Camera |
| Camera | Stephen McBride | First Assistant "B" Camera |
| Editing | Lance Spindler | Color Timer |
| Camera | Jonathan Furmanski | Additional Photography |
| Editing | Annalise Kurinsky | Digital Intermediate Producer |
| Sound | Spencer Cohen | Musician |
| Camera | Corey Braccone | Grip |
| Editing | Doug Delaney | Digital Intermediate Colorist |
| Production | Libby Allen | Production Assistant |
| Costume & Make-Up | Linda Kaufman | Key Makeup Artist |
