Het is 1988. Studenten Abby en Gretchen zijn al heel lang beste vriendinnen. Maar nadat een avondje naaktzwemmen rampzalig misgaat, begint Gretchen zich anders te gedragen. Ze is humeurig, prikkelbaar en er gebeuren steeds bizarre dingen als ze in de buurt is. Abby's onderzoek leidt haar naar een aantal verrassende ontdekkingen. Tegen de tijd dat hun verhaal zijn angstaanjagende conclusie bereikt, zal het lot van Abby en Gretchen worden bepaald door een enkele vraag: is hun vriendschap sterk genoeg om de duivel te verslaan?
Nee, helaas is My Best Friend's Exorcism nog niet beschikbaar op Netflix in Nederland.
| Writing | Grady Hendrix | Novel |
| Directing | Damon Thomas | Director |
| Production | Christopher Landon | Producer |
| Production | Ellen Goldsmith-Vein | Producer |
| Editing | Brad Turner | Editor |
| Art | Bruce Curtis | Production Design |
| Art | Julian Scalia | Art Direction |
| Costume & Make-Up | Ariyela Wald-Cohain | Costume Design |
| Production | Michael Flynn | Unit Production Manager |
| Directing | Stephen W. Moore | First Assistant Director |
| Directing | John Bonaccorse | Second Unit Director |
| Crew | William Scharpf | Stunt Coordinator |
| Camera | Rob Givens | Director of Photography |
| Crew | Brooklyn Proctor | Stunt Double |
| Art | Jon Sandmaier | Set Designer |
| Art | Laura Wallgren | Set Decoration |
| Art | Shawn Upthegrove | Leadman |
| Directing | Christopher M. Searcey | Script Supervisor |
| Visual Effects | David Fletcher | Special Effects Supervisor |
| Costume & Make-Up | Ginger Knussmann | Key Costumer |
| Costume & Make-Up | Lydia Graboski-Bauer | Costume Supervisor |
| Costume & Make-Up | Katie Ballard | Hair Department Head |
| Costume & Make-Up | Sonya Riviere | Key Hair Stylist |
| Costume & Make-Up | Tess Laeh | Key Makeup Artist |
| Costume & Make-Up | Micah Laine | Makeup Department Head |
| Production | Jason Underwood | Location Manager |
| Production | Joesph Gagliardi | Assistant Location Manager |
| Production | Tiffany D. Moore | Production Coordinator |
| Art | David H. Nash | Construction Coordinator |
| Crew | Terry Collis | Transportation Coordinator |
| Crew | Isabel Henderson | Post Production Supervisor |
| Editing | Peter Gvozdas | Additional Editor |
| Sound | Ryland Blackinton | Original Music Composer |
| Editing | Gareth Spensley | Colorist |
| Visual Effects | Philippe Thibault | VFX Supervisor |
| Visual Effects | Philippe Massonnat | Visual Effects Producer |
| Art | Hsien Lun Su | Title Designer |
| Art | Aaron Becker | Title Designer |
| Writing | Jenna Lamia | Teleplay |
| Production | David Borgenicht | Producer |
| Production | Jennifer Semler | Producer |
| Production | Michael Flynn | Executive Producer |
| Production | Grady Hendrix | Executive Producer |
| Production | Katherine McGuire | Executive Producer |
| Production | Lindsay Williams | Executive Producer |
| Production | Jenna Lamia | Associate Producer |
| Production | Stephen W. Moore | Co-Producer |
| Sound | Rob Lowry | Music Supervisor |
| Production | Mary Vernieu | Casting |
| Production | Lindsay Graham Ahanonu | Casting |
| Art | Alexander K. Riba | Set Dresser |
| Sound | Emily Bender | Music Coordinator |
| Sound | Mia Riggins | Music Coordinator |
| Sound | Robert Cotnoir | Music Editor |
| Sound | Brett Murray | Sound Mixer |
| Sound | Colin Alexander | Dialogue Editor |
| Sound | Dean St. John | ADR Mixer |
| Sound | Ric Schnupp | Supervising Sound Editor |
| Sound | Jeffrey Roy | ADR Mixer |
| Sound | Greg Crawford | ADR Mixer |
| Sound | Chris Foster | Supervising Sound Editor |
| Sound | Rich Macar | ADR Recordist |
| Sound | Bill Orrico | Dialogue Editor |
| Sound | Rene Coronado | ADR Engineer |
| Art | Lauren Mosley | Set Dresser |
| Lighting | Kyle Z. Anderson | Lighting Technician |
| Camera | Keith Cutler | Key Grip |
| Camera | Mark Gilmer | Digital Imaging Technician |
| Lighting | Ryan Perdew | Gaffer |
| Camera | Trevor Rios | First Assistant "A" Camera |
| Camera | Sterling Wiggins | First Assistant "B" Camera |
| Camera | Tyler Bastianson | Second Assistant Camera |
| Production | Rose Locke | Extras Casting |
| Editing | Serena Forghieri | First Assistant Editor |
| Editing | Theresa Crooks | Color Assistant |
| Editing | Chase Commins | Dailies Operator |
| Camera | Eliza Morse | Still Photographer |
