Zeke en William zijn rechercheurs die samen onderzoek doen naar een reeks gruwelijke misdaden. Ook Marcus, de vader van Zeke, wordt op de zaak gezet. De moordenaar blijkt het gemunt te hebben op de politie. Gaandeweg wordt duidelijk dat de zaak te maken heeft met Jigsaw en dat het werk van laatstgenoemde wordt voortgezet.
Nee, helaas is Spiral: From the Book of Saw nog niet beschikbaar op Netflix in Nederland.
| Editing | Dev Singh | Editor |
| Production | Stacey Testro | Executive Producer |
| Production | Kevin Greutert | Executive Producer |
| Production | Gregg Hoffman | Executive Producer |
| Production | Jason Constantine | Executive Producer |
| Production | Ketura Kestin | Co-Producer |
| Costume & Make-Up | Silvia Platsis | Makeup Artist |
| Costume & Make-Up | Keirsten Morris | Key Makeup Artist |
| Production | Stephanie Gorin | Casting |
| Costume & Make-Up | Randy Daudlin | Makeup Department Head |
| Production | Peter Block | Executive Producer |
| Costume & Make-Up | Patrick Baxter | Special Effects Makeup Artist |
| Sound | Ormangoren Gurkan | Boom Operator |
| Sound | Mark Wilkening | ADR Mixer |
| Sound | Robert Woolfson | Sound Mixer |
| Crew | Hugh Goodden | Special Effects Technician |
| Sound | Angelo Raguso | Sound Designer |
| Visual Effects | Jon Campfens | Visual Effects Supervisor |
| Visual Effects | Peter Denomme | Visual Effects Producer |
| Visual Effects | Tobias Kreißl | Visual Effects Supervisor |
| Visual Effects | Tim Luecker | Visual Effects Producer |
| Lighting | Ira Cohen | Gaffer |
| Sound | Emilie Boucek | Sound Editor |
| Sound | Simon Miminis | Music Editor |
| Production | Paul Franklin | Location Manager |
| Sound | Jordan Burg | Music Supervisor |
| Directing | Nadia Guglieri | Script Supervisor |
| Sound | William Kellerman | Foley Artist |
| Sound | Jeffrey Roy | ADR Mixer |
| Visual Effects | Rafael Pacheco | Visual Effects Coordinator |
| Sound | Ahmar Bailey | Music Producer |
| Sound | Tom Bjelic | Sound Editor |
| Sound | John Laing | Sound Editor |
| Sound | Daniel Moctezuma | Foley Recordist |
| Visual Effects | Pablo José Fuertes | Visual Effects Supervisor |
| Visual Effects | Beau Parsons | Visual Effects Supervisor |
| Sound | Scott Greer | Music Supervisor |
| Sound | Keith Elliott | Sound Re-Recording Mixer |
| Sound | Steve Baine | Foley Artist |
| Sound | Mark Zsifkovits | Sound Re-Recording Mixer |
| Sound | Xerxes Shuzhang Yang | Sound Editor |
| Crew | Shawn Morris | Special Effects Technician |
| Sound | Mark Gingras | Supervising Sound Editor |
| Art | Dhaval Jasani | Location Scout |
| Visual Effects | Jeff Skochko | Special Effects Supervisor |
| Art | Marc R. Taylor | Set Dresser |
| Art | Farris Popat | Set Dresser |
| Costume & Make-Up | François Dagenais | Special Effects Makeup Artist |
| Art | Ines Rose | Art Direction |
| Writing | James Wan | Characters |
| Writing | Leigh Whannell | Characters |
| Production | Marc Dassas | Production Manager |
| Directing | Jonnie Katz | Second Assistant Director |
| Crew | Robert Racki | Stunt Coordinator |
| Crew | Philip Stilman | Post Production Supervisor |
| Crew | Mark Schneider | Stunts |
| Crew | Billy Oliver | Stunts |
| Crew | Kiante Elam | Stunt Double |
| Crew | Branko Racki | Stunt Coordinator |
| Crew | Curtis Parker | Stunt Double |
| Crew | Branko Racki | Stunts |
| Crew | Mike Chute | Stunts |
| Directing | David Sparkes | First Assistant Director |
| Crew | Eric Daniel | Stunt Double |
| Crew | Joseph Racki | Stunt Double |
| Crew | Mike Gow | Stunts |
| Crew | Mark Schneider | Stunt Driver |
| Crew | Ermes Blarasin | Stunts |
| Crew | Shelley Cook | Stunts |
| Camera | Michael Fylyshtan | Steadicam Operator |
| Sound | Andy Gershon | Music Supervisor |
| Art | David Lewington | Assistant Art Director |
| Crew | Dylan Rampulla | Stunt Double |
| Crew | Cecil Philips | Stunts |
| Art | Olivia Edmonds | Art Department Coordinator |
| Art | Kris Kearns | Set Dresser |
| Costume & Make-Up | Keirsten Morris | Makeup Artist |
| Costume & Make-Up | Alexander Narizni | On Set Dresser |
| Costume & Make-Up | Vann E. Gouweleeuw | Assistant Makeup Artist |
| Camera | Rion Gonzales | Camera Operator |
| Art | Stefano Amelio | Set Dresser |
| Camera | Michael Fylyshtan | Camera Operator |
| Art | Michael Nesbitt | Assistant Art Director |
| Costume & Make-Up | Lisa Deveaux | Makeup Artist |
| Camera | Liam Ward | Camera Operator |
| Directing | Josh Keller | Third Assistant Director |
| Art | Martin Budd | Set Dresser |
| Costume & Make-Up | Kevin Barry | Assistant Costume Designer |
| Costume & Make-Up | Jennelle Greene | Assistant Makeup Artist |
| Camera | Liam Ward | Steadicam Operator |
| Art | David Lewington | Set Designer |
| Costume & Make-Up | François Dagenais | Prosthetic Designer |
| Crew | Torianna Lee | Stunt Double |
| Crew | Billy Oliver | Stunt Driver |
| Crew | Scott Cook | Stunt Driver |
| Directing | Kristen Calibaba | Third Assistant Director |
| Costume & Make-Up | Allison Mondesir | Hair Department Head |
| Costume & Make-Up | Donna Hunt | Hairstylist |
| Costume & Make-Up | Marcos Smith | Hairstylist |
| Costume & Make-Up | Paulina Harcus | Key Hair Stylist |
| Crew | Patrick Baxter | Makeup Effects |
| Crew | Traci Loader | Makeup Effects |
| Writing | Pete Goldfinger | Writer |
| Production | Mark Burg | Producer |
| Directing | Darren Lynn Bousman | Director |
| Writing | Josh Stolberg | Writer |
| Production | Oren Koules | Producer |
| Art | Terri Drennan | Set Decoration |
| Production | James Wan | Executive Producer |
| Production | Leigh Whannell | Executive Producer |
| Production | Daniel J. Heffner | Executive Producer |
| Art | Greg Chown | Art Direction |
| Costume & Make-Up | Laura Montgomery | Costume Design |
| Art | Anthony Cowley | Production Design |
| Production | Chris Rock | Executive Producer |
| Camera | Jordan Oram | Director of Photography |
| Sound | Charlie Clouser | Original Music Composer |
| Sound | 21 Savage | Songs |
