Gregorio is een ouderwetse bankier, supporter van Real Madrid en een oude mopperpot. Wanneer zijn vrouw plots overlijdt moet hij haar laatste wens vervullen: haar as uitstrooien in de rivier de Guadalquivir. Om dit te doen brengt hij samen met zijn kinderen het weekend door in Sanlucar, waar de rivier uitmondt. Daar ontmoet hij de partners van zijn twee dochters: een supporter van FC Barcelona en een hippie. Ook met zijn zoon, met wie hij geen woord spreekt sinds hij uit de kast kwam, en diens vriend zal hij het weekend moeten zien door te komen.
Nee, helaas is Señor, dame paciencia nog niet beschikbaar op Netflix in Nederland.
| Production | Eduardo Campoy | Executive Producer |
| Production | Rocio Esperilla | Executive Producer |
| Production | Mercedes Gamero | Producer |
| Production | Mikel Lejarza | Producer |
| Production | José Manuel Lorenzo | Producer |
| Production | Juan Moreno | Executive Producer |
| Sound | Julio de la Rosa | Original Music Composer |
| Camera | Valentín Álvarez | Director of Photography |
| Editing | Verónica Callón | Editor |
| Production | Juana Martínez | Casting |
| Art | Óscar Sempere | Production Design |
| Costume & Make-Up | Saioa Lara | Costume Design |
| Costume & Make-Up | Lourdes Briones | Makeup Artist |
| Costume & Make-Up | Julia Garrido | Makeup Artist |
| Costume & Make-Up | Susana Gonsálvez | Makeup Artist |
| Costume & Make-Up | Mariló Osuna | Makeup Artist |
| Costume & Make-Up | Carmen Veinat | Hairstylist |
| Directing | Aldonza Gómez | Script Supervisor |
| Crew | Pablo Carbonell | Thanks |
| Directing | Carmen Torres | Second Assistant Director |
| Directing | Mireia Hidalgo | Third Assistant Director |
| Directing | Marta Sabell | First Assistant Director |
| Sound | Miguel Barbosa | Foley Artist |
| Sound | Gabriel Gutiérrez | Sound |
| Sound | Iñaki Sánchez-Elvira | Dialogue Editor |
| Sound | Diego S. Staub | Foley Mixer |
| Sound | Patricia Milanesi | Sound |
| Sound | Ignacio Arrojo | ADR Recordist |
| Camera | Manu Trillo | Still Photographer |
| Camera | Julio Vergne | Still Photographer |
| Crew | Valentín Álvarez | Photoscience Manager |
| Directing | Álvaro Díaz Lorenzo | Director |
| Writing | Álvaro Díaz Lorenzo | Writer |
| Visual Effects | Vanessa G. Iglesias | Visual Effects Supervisor |
| Production | Antonio P. Pérez | Co-Producer |
| Sound | Jorge Marín | Sound Recordist |
| Sound | Alfredo Díaz | Sound Designer |
| Sound | Nicolás de Poulpiquet | Sound Re-Recording Mixer |
| Costume & Make-Up | Antonio Panizza | Makeup & Hair |
| Directing | Rocío Ballesteros | Additional Second Assistant Director |
| Art | Ignacio de Marcos | Storyboard Artist |
| Production | César Romero | Unit Production Manager |
| Camera | Tito Carlón | "A" Camera Operator |
| Camera | Luigi Martin | "B" Camera Operator |
| Camera | Luigi Martin | Second Unit Director of Photography |
| Camera | Cuco de la Peña | First Assistant "A" Camera |
| Camera | Sergio Andrés Montero | First Assistant "B" Camera |
| Camera | Rodrigo Loro | Second Assistant "A" Camera |
| Camera | Paco Cano | Second Assistant "B" Camera |
| Camera | Dani Lisón | Digital Imaging Technician |
| Sound | Álvaro Silva Wuth | Boom Operator |
| Sound | Sara Marín Santaella | Sound Assistant |
| Art | Lala Obrero | Set Designer |
| Art | Alejandra Loiseau | Art Department Assistant |
| Art | Marta Gutiérrez Abad | Property Master |
| Art | Meme Mateos | Property Master |
| Art | Enrique Garrido | Standby Property Master |
| Art | Valentín Isakov | Set Dresser |
| Art | José María Ortega | Additional Set Dresser |
| Art | David Martínez Davo | Additional Set Dresser |
| Art | Ángel Madueño | Additional Set Dresser |
| Lighting | Ignacio Romanillos | Gaffer |
| Camera | Alfredo Díaz | Key Grip |
| Crew | Guillermo Sempere | Post Production Supervisor |
| Visual Effects | Helen Martí Donoghue | Visual Effects Coordinator |
| Art | Álvaro León Acosta | Title Designer |
| Art | Luis León Acosta | Title Designer |
| Art | Virginia Velasco | Title Designer |
