Tien jaar is er verstreken sinds Sidney Prescott (Neve Campbell) haar laatste confrontatie had met de gemaskerde moordenaar Ghostface. Ze leeft nu geïsoleerd en heeft een boek geschreven dat veel lovende kritieken heeft ontvangen. Ze wordt echter uit haar dagelijkse routine getrokken als Ghostface weer verschijnt in Michigan, met als gevolg dat Sidney weer herenigd wordt met Dewey (David Arquette) en Gale (Courtney Cox).
Nee, helaas is Scream 4 nog niet beschikbaar op Netflix in Nederland.
| Directing | Wes Craven | Director |
| Writing | Kevin Williamson | Characters |
| Camera | Peter Deming | Director of Photography |
| Production | Kevin Williamson | Producer |
| Production | Wes Craven | Producer |
| Production | Marianne Maddalena | Executive Producer |
| Production | Ron Schmidt | Executive Producer |
| Writing | Kevin Williamson | Screenplay |
| Crew | Brian Avery | Stunts |
| Crew | Karin Silvestri | Stunts |
| Art | Adam Stockhausen | Production Design |
| Production | Bob Weinstein | Executive Producer |
| Production | Harvey Weinstein | Executive Producer |
| Production | Ehren Kruger | Executive Producer |
| Sound | Marco Beltrami | Music |
| Editing | Peter McNulty | Editor |
| Production | Avy Kaufman | Casting |
| Production | Nancy Nayor | Casting |
| Art | Gerald Sullivan | Art Direction |
| Art | Helen Britten | Set Decoration |
| Costume & Make-Up | Debra McGuire | Costume Design |
| Crew | William Bernardin | In Memory Of |
| Crew | Renae Moneymaker | Stunts |
| Crew | Karin Silvestri | Stunt Double |
| Crew | Ann Scott | Stunt Double |
| Crew | Dana Reed | Stunt Double |
| Crew | Dailyn Matthews | Stunts |
| Crew | Cassidy Vick Hice | Stunt Double |
| Crew | Stacey Carino | Stunt Double |
| Crew | Allison Caetano | Stunt Double |
| Production | Iya Labunka | Producer |
| Production | Matthew Stein | Executive Producer |
| Production | Cathy Konrad | Executive Producer |
| Production | Carly Feingold | Co-Producer |
| Sound | Liza Richardson | Music Supervisor |
| Production | Ron Schmidt | Unit Production Manager |
| Directing | Nicholas Mastandrea | First Assistant Director |
| Directing | Maria Mantia | Second Assistant Director |
| Crew | Troy Brown | Stunt Coordinator |
| Crew | Riley Harper | Stunt Double |
| Crew | Banzai Vitale | Stunt Driver |
| Production | Richard E. Chapla Jr. | Production Supervisor |
| Crew | Eric Bergman | Post Production Supervisor |
| Crew | Patrick Esposito | Post Production Supervisor |
| Editing | Brendan Walsh | Additional Editor |
| Camera | David Eubank | First Assistant "A" Camera |
| Camera | Claire Farrand-Stone | Second Assistant "A" Camera |
| Camera | George Billinger III | "B" Camera Operator |
| Sound | Jeffree Bloomer | Production Sound Mixer |
| Directing | Anastacia C. Nemec | Second Second Assistant Director |
| Directing | Lori Grabowski | Script Supervisor |
| Lighting | Jay Fortune | Gaffer |
| Camera | Philip Sloan | Key Grip |
| Art | J.P. Jones | Property Master |
| Costume & Make-Up | Diane Crooke | Costume Supervisor |
| Costume & Make-Up | Joy Zapata | Hair Department Head |
| Costume & Make-Up | Peter Robb-King | Makeup Department Head |
| Production | M.K. Gleason | Production Accountant |
| Production | Georgina Marquis | Production Coordinator |
| Production | Logan Cooper | Location Manager |
| Visual Effects | Ron Bolanowski | Special Effects Supervisor |
| Art | Jody Gaber | Art Department Coordinator |
| Art | Emma Stensaas | Art Department Assistant |
| Art | Thomas Traugott | Leadman |
| Camera | Gemma La Mana | Still Photographer |
| Camera | Phil Bray | Still Photographer |
| Sound | Anthony Cargioli | Boom Operator |
| Costume & Make-Up | Catherine Hahn | Key Costumer |
| Costume & Make-Up | Jennifer Kamrath | Key Costumer |
| Costume & Make-Up | Kristi Hoffman | Set Costumer |
| Costume & Make-Up | Megan Wiser | Costumer |
| Costume & Make-Up | Maggie Fung | Key Makeup Artist |
| Costume & Make-Up | Norma Lee | Key Hair Stylist |
| Costume & Make-Up | Dawn Mattocks | Hairstylist |
| Costume & Make-Up | Gary J. Tunnicliffe | Prosthetic Designer |
| Art | Skip Crank | Assistant Property Master |
| Lighting | Brian McClean | Best Boy Electric |
| Lighting | Brad Irvin | Electrician |
| Lighting | Anthony 'Spike' Simms | Rigging Gaffer |
| Camera | Paul Wilkowsky | Best Boy Grip |
| Camera | Steve Alessi | Grip |
| Camera | Brandon Cundiff | Grip |
| Camera | Spencer M. Rohan | Grip |
| Camera | Kevin Fannon | Grip |
| Camera | Tony Boura | Grip |
| Art | Ronald Napier | Construction Foreman |
| Art | Tina Tottis | Set Decoration Buyer |
| Production | Ryan Gomez | First Assistant Accountant |
| Production | Kelly Stultz | Payroll Accountant |
| Production | M.K. Shaw | Payroll Accountant |
| Editing | Blair Miller | First Assistant Editor |
| Sound | Todd Toon | Sound Designer |
| Sound | Todd Toon | Supervising Sound Editor |
| Sound | Donald J. Malouf | Supervising Sound Editor |
| Sound | Donald J. Malouf | Sound Designer |
| Sound | Victoria Rose Sampson | Supervising ADR Editor |
| Sound | Charles W. Ritter | Sound Editor |
| Sound | John Kwiatkowski | Sound Editor |
| Sound | Odin Benitez | Sound Editor |
| Sound | Albert Gasser | Sound Editor |
| Sound | G.W. Brown | ADR Editor |
| Sound | Val Kuklowsky | ADR Editor |
| Sound | Pernell L. Salinas | First Assistant Sound Editor |
| Sound | Patrick Cyccone Jr. | Sound Re-Recording Mixer |
| Sound | Christian P. Minkler | Sound Re-Recording Mixer |
| Sound | Joe Barnett | Additional Sound Re-Recording Mixer |
| Sound | Darrin Mann | Foley Mixer |
| Sound | Catherine Harper | Foley Artist |
| Sound | Christopher Moriana | Foley Artist |
| Sound | Greg Steele | ADR Mixer |
| Sound | Robert Deschaine | ADR Mixer |
| Sound | Ron Bedrosian | ADR Mixer |
| Sound | Dean St. John | ADR Mixer |
| Sound | Doc Kane | ADR Mixer |
| Sound | Greg Zimmerman | ADR Recordist |
| Sound | Tami Treadwell | ADR Recordist |
| Sound | Julio Carmona | ADR Recordist |
| Sound | Julie Altus | ADR Recordist |
| Crew | Marcus Trumpp | Additional Music |
| Crew | Brandon Roberts | Additional Music |
| Crew | Dennis Smith | Additional Music |
| Crew | John Paesano | Additional Music |
| Sound | Ben Schor | Music Editor |
| Production | Leeba Zakharov | Casting Associate |
| Production | Sabrina Hyman | Casting Associate |
| Production | Charles L. Gariepy | Casting Associate |
| Production | Andy Henry | Casting Associate |
| Editing | Carl S.G. Moore | Digital Intermediate Producer |
| Editing | Mark Sahagun | Digital Intermediate Editor |
| Art | Bruce Schluter | Title Designer |
| Visual Effects | Jon Cowley | VFX Supervisor |
| Visual Effects | Keith Devlin | Compositing Supervisor |
| Crew | Mathew Giampa | Compositor |
| Crew | Trevor Strand | Compositor |
| Art | Kurt Braun | Set Dresser |
| Art | Sarah Ivey | Set Dresser |
| Art | Mark Sejnowski | Set Dresser |
| Visual Effects | Michael D'Sa | Visual Effects Producer |
| Visual Effects | Shome Dasgupta | Visual Effects Producer |
| Visual Effects | Jamison Scott Goei | Visual Effects Supervisor |
| Visual Effects | Arushi Govil | VFX Artist |
| Visual Effects | Reupal D Rawal | Visual Effects Supervisor |
| Crew | Dane Farwell | Stunts |
